1,235 research outputs found
The Measurement of Absorptive Capacity from an Economics Perspective: Definition, Measurement and Importance
This paper starts by recognizing that despite the importance of absorptive capacity, economists in particular have made only limited use of the concept. Most theoretical and empirical studies derive from other fields of research. Thus, the first task is to compare and contrast the different approaches taken in measuring absorptive capacity. The rest of the paper then sets out an example of how typically economists have proceeded, using nationally representative CIS data to measure absorptive capacity across a 10âyear period and investigating if it remains stable in the long term. This is followed by considering how firmsâ characteristics vary across lower to higher levels of absorptive capacity and whether such capacity determines firmsâ productivity performance across both goods and service industries. Our results show that relative to other influences, absorptive capacity as measured here â net of the impact of foreignâownership and human capital â has a substantial influence on exporting, innovation and undertaking R&D and thus consequently firmâlevel productivity. Finally, there is a discussion of why governments should consider helping firms to boost their levels of absorptive capacity
STATIC FOUR-DIMENSIONAL ABELIAN BLACK HOLES IN KALUZA-KLEIN THEORY
Static, four-dimensional (4-d) black holes (BH's) in ()-d Kaluza-Klein
(KK) theory with Abelian isometry and diagonal internal metric have at most one
electric () and one magnetic () charges, which can either come from the
same -gauge field (corresponding to BH's in effective 5-d KK theory) or
from different ones (corresponding to BH's with isometry
of an effective 6-d KK theory). In the latter case, explicit non-extreme
solutions have the global space-time of Schwarzschild BH's, finite temperature,
and non-zero entropy. In the extreme (supersymmetric) limit the singularity
becomes null, the temperature saturates the upper bound
, and entropy is zero. A class of KK BH's with
constrained charge configurations, exhibiting a continuous electric-magnetic
duality, are generated by global transformations on the above classes
of the solutions.Comment: 11 pages, 2 Postscript figures. uses RevTeX and psfig.sty (for figs)
paper and figs also at ftp://dept.physics.upenn.edu/pub/Cvetic/UPR-645-
Thermodynamic and gravitational instability on hyperbolic spaces
We study the properties of anti--de Sitter black holes with a Gauss-Bonnet
term for various horizon topologies (k=0, \pm 1) and for various dimensions,
with emphasis on the less well understood k=-1 solution. We find that the zero
temperature (and zero energy density) extremal states are the local minima of
the energy for AdS black holes with hyperbolic event horizons. The hyperbolic
AdS black hole may be stable thermodynamically if the background is defined by
an extremal solution and the extremal entropy is non-negative. We also
investigate the gravitational stability of AdS spacetimes of dimensions D>4
against linear perturbations and find that the extremal states are still the
local minima of the energy. For a spherically symmetric AdS black hole
solution, the gravitational potential is positive and bounded, with or without
the Gauss-Bonnet type corrections, while, when k=-1, a small Gauss-Bonnet
coupling, namely, \alpha << {l}^2 (where l is the curvature radius of AdS
space), is found useful to keep the potential bounded from below, as required
for stability of the extremal background.Comment: Shortened to match published (PRD) version, 18 pages, several eps
figure
Supersymmetry and the positron excess in cosmic rays
Recently the HEAT balloon experiment has confirmed an excess of high-energy
positrons in cosmic rays. They could come from annihilation of dark matter in
the galactic halo. We discuss expectations for the positron signal in cosmic
rays from the lightest superpartner. The simplest interpretations are
incompatible with the size and shape of the excess if the relic LSPs evolved
from thermal equilbrium. Non-thermal histories can describe a sufficient
positron rate. Reproducing the energy spectrum is more challenging, but perhaps
possible. The resulting light superpartner spectrum is compatible with collider
physics, the muon anomalous magnetic moment, Z-pole electroweak data, and other
dark matter searches.Comment: 4 pages, 2 figures, references added, minor wording change
Slowly rotating charged black holes in anti-de Sitter third order Lovelock gravity
In this paper, we study slowly rotating black hole solutions in Lovelock
gravity (n=3). These exact slowly rotating black hole solutions are obtained in
uncharged and charged cases, respectively. Up to the linear order of the
rotating parameter a, the mass, Hawking temperature and entropy of the
uncharged black holes get no corrections from rotation. In charged case, we
compute magnetic dipole moment and gyromagnetic ratio of the black holes. It is
shown that the gyromagnetic ratio keeps invariant after introducing the
Gauss-Bonnet and third order Lovelock interactions.Comment: 14 pages, no figur
Dysfunctional Dopaminergic Neurones in Mouse Models of Huntington's Disease: A Role for SK3 Channels
Background:
Huntington's disease (HD) is a late-onset fatal neurodegenerative disorder caused by a CAG trinucleotide repeat expansion in the gene coding for the protein huntingtin and is characterised by progressive motor, psychiatric and cognitive decline. We previously demonstrated that normal synaptic function in HD could be restored by application of dopamine receptor agonists, suggesting that changes in the release or bioavailability of dopamine may be a contributing factor to the disease process.
Objective:
In the present study, we examined the properties of midbrain dopaminergic neurones and dopamine release in presymptomatic and symptomatic transgenic HD mice.
Methods and Results:Using intracellular sharp recordings and immunohistochemistry, we found that neuronal excitability was increased due to a loss of slow afterhyperpolarisation and that these changes were related to an apparent functional loss and abnormal distribution of SK3 channels (KCa2.3 encoded by the KCNN3 gene), a class of small-conductance calcium-activated potassium channels. Electrochemical detection of dopamine showed that this observation was associated with an enhanced dopamine release in presymptomatic transgenic mice and a drastic reduction in symptomatic animals. These changes occurred in the context of a progressive expansion in the CAG repeat number and nuclear localisation of mutant protein within the substantia nigra pars compacta.
Conclusions:
Dopaminergic neuronal dysfunction is a key early event in HD disease progression. The initial increase in dopamine release appears to be related to a loss of SK3 channel function, a protein containing a polyglutamine tract. Implications for polyglutamine-mediated sequestration of SK3 channels, dopamine-associated DNA damage and CAG expansion are discussed in the context of HD.</br
Braneworld Cosmology in (Anti)--de Sitter Einstein--Gauss--Bonnet--Maxwell Gravity
Braneworld cosmology for a domain wall embedded in the charged (Anti)-de
Sitter-Schwarzschildblack hole of the five--dimensional
Einstein-Gauss-Bonnet-Maxwell theory is considered. The effective Friedmann
equation for the brane is derived by introducing the necessary surface
counterterms required for a well-defined variational principlein the
Gauss--Bonnet theory and for the finiteness of the bulk space. The asymptotic
dynamics of the brane cosmology is determined and it is found that solutions
with vanishingly small spatial volume are unphysical. The finiteness of the
bulk action is related to the vanishing of the effective cosmological constant
on the brane. An analogy between the Friedmann equation and a generalized
Cardy--Verlinde formula is drawn.Comment: LaTex file 28 pages, typos corrected, one reference is adde
B-Pol: Detecting Primordial Gravitational Waves Generated During Inflation
B-Pol is a medium-class space mission aimed at detecting the primordial
gravitational waves generated during inflation through high accuracy
measurements of the Cosmic Microwave Background (CMB) polarization. We discuss
the scientific background, feasibility of the experiment, and implementation
developed in response to the ESA Cosmic Vision 2015-2025 Call for Proposals.Comment: Experimental Astronomy - The original publication is available at
http://www.springerlink.co
Nonparametric nonlinear model predictive control
Model Predictive Control (MPC) has recently found wide acceptance in industrial applications, but its potential has been much impeded by linear models due to the lack of a similarly accepted nonlinear modeling or databased technique. Aimed at solving this problem, the paper addresses three issues: (i) extending second-order Volterra nonlinear MPC (NMPC) to higher-order for improved prediction and control; (ii) formulating NMPC directly with plant data without needing for parametric modeling, which has hindered the progress of NMPC; and (iii) incorporating an error estimator directly in the formulation and hence eliminating the need for a nonlinear state observer. Following analysis of NMPC objectives and existing solutions, nonparametric NMPC is derived in discrete-time using multidimensional convolution between plant data and Volterra kernel measurements. This approach is validated against the benchmark van de Vusse nonlinear process control problem and is applied to an industrial polymerization process by using Volterra kernels of up to the third order. Results show that the nonparametric approach is very efficient and effective and considerably outperforms existing methods, while retaining the original data-based spirit and characteristics of linear MPC
Gravitational hedgehog, stringy hedgehog and stringy sphere
We investigate the solutions of Einstein equations such that a hedgehog
solution is matched to different exterior or interior solutions via a spherical
shell. In the case where both the exterior and the interior regions are
hedgehog solutions or one of them is flat, the resulting spherical shell
becomes a stringy shell. We also consider more general matchings and see that
in this case the shell deviates from its stringy character.Comment: 11 page
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