MIDMs: Matching Interleaved Diffusion Models for Exemplar-based Image Translation

We present a novel method for exemplar-based image translation, called matching interleaved diffusion models (MIDMs). Most existing methods for this task were formulated as GAN-based matching-then-generation framework. However, in this framework, matching errors induced by the difficulty of semantic matching across cross-domain, e.g., sketch and photo, can be easily propagated to the generation step, which in turn leads to degenerated results. Motivated by the recent success of diffusion models overcoming the shortcomings of GANs, we incorporate the diffusion models to overcome these limitations. Specifically, we formulate a diffusion-based matching-and-generation framework that interleaves cross-domain matching and diffusion steps in the latent space by iteratively feeding the intermediate warp into the noising process and denoising it to generate a translated image. In addition, to improve the reliability of the diffusion process, we design a confidence-aware process using cycle-consistency to consider only confident regions during translation. Experimental results show that our MIDMs generate more plausible images than state-of-the-art methods

Optimum Design of Quenching Capacitor Integrated Silicon Photomultipliers for TOF-PET Application

AbstractThe prototype SiPM was designed and fabricated for MRI compatible PET using the customized CMOS process at National Nanofab Center in KAIST. The SiPM was designed to have a size of 3x3 mm2 composed of micro-cells of 65x65μm2 with a fill factor of 68%. The size of a micro-cell was determined by optimization between the photon detection efficiency (PDE) and the dynamic range for the photons of 511 keV from LYSO crystal. In the micro-cell structure, a specially designed quenching capacitor (QC) is added parallel to quenching resistor using the Metal-Insulator-Metal (MIM) process. This QC integrated SiPMs (QC-SiPM) was devised to realize rapid response of output pulses and to enhance the timing resolution of SiPM. Coincidence timing resolution of PET detectors depends on the output pulse shapes which are the convolution of the intrinsic pulse shape of scintillation crystals and the single photon pulse shape at the micro-cell in a SiPM. A quenching capacitor parallel to a quenching resistor provides a fast current path at the beginning stage of avalanche process, than reduces rising time of single photon pulse shape. In this study the rise time of the QC-SiPM signal was analyzed to be 22.5ns while that for the regular SiPM was 34.3ns

DiffMatch: Diffusion Model for Dense Matching

The objective for establishing dense correspondence between paired images consists of two terms: a data term and a prior term. While conventional techniques focused on defining hand-designed prior terms, which are difficult to formulate, recent approaches have focused on learning the data term with deep neural networks without explicitly modeling the prior, assuming that the model itself has the capacity to learn an optimal prior from a large-scale dataset. The performance improvement was obvious, however, they often fail to address inherent ambiguities of matching, such as textureless regions, repetitive patterns, and large displacements. To address this, we propose DiffMatch, a novel conditional diffusion-based framework designed to explicitly model both the data and prior terms. Unlike previous approaches, this is accomplished by leveraging a conditional denoising diffusion model. DiffMatch consists of two main components: conditional denoising diffusion module and cost injection module. We stabilize the training process and reduce memory usage with a stage-wise training strategy. Furthermore, to boost performance, we introduce an inference technique that finds a better path to the accurate matching field. Our experimental results demonstrate significant performance improvements of our method over existing approaches, and the ablation studies validate our design choices along with the effectiveness of each component. Project page is available at https://ku-cvlab.github.io/DiffMatch/.Comment: Project page is available at https://ku-cvlab.github.io/DiffMatch

Synthesis of Eu-doped (Gd,Y) 2 O 3 transparent optical ceramic scintillator

A novel process for transparent oxide ceramic scintillator with a composition of Gd 1.94-x Y x Eu 0.06 O 3 was developed. The process consists of a glycine-nitrate combustion synthesis of nano-sized starting powder and subsequent controlled sintering and annealing steps. The organic molecules remaining in the as-combusted powder were efficiently removed by the combined heat-treatment at vacuum and air atmospheres. Hot-pressed ceramic scintillators show transparent optical state and high light output. Transparent optical ceramic scintillator with a high content of Gd (up to 80 mol%) was fabricated by the process. The measured light output of Gd 1.54 Y 0.4 Eu 0.06 O 3 ceramic scintillator was about two times higher that that of CdWO 4 single crystal. In a typical radiation detection system, the scintillator plays the key role of converting the incident energy of ionizing radiation into scintillation light photons, then the emitted lights are collected by the under-laid photosensor. This specific application requires an ideal scintillator that has high light output, fast decay property, low afterglow, and so forth. Recently, a large number of new scintillator systems has been reviewed, 1 resulting, in part, with the development of a new class of scintillator: the polycrystalline ceramic scintillator

Measurements of 1/f noise in A-Si:H pin diodes and thin-film-transistors

We measured the equivalent noise charge of a-Si:H pin diodes (5 {approximately} 45{mu}m i-layer) with a pulse shaping time of 2.5 {mu}sec under reverse biases up to 30 V/{mu}m and analyzed it as a four component noise source. The frequency spectra of 1/f noise on the soft-breakdown region and of the Nyquist noise from contact resistance of diodes were measured. Using the conversion equations for a CR-RC shaper, we identified the contact resistance noise and the 1/f noise as the main noise sources in the low bias and high bias regions respectively. The 1/f noise of a-Si:H TFTs with channel length of 15 {mu}m was measured to be the dominant component up to {approximately}100kHz for both saturation and linear regions. 15 refs., 7 figs

Reducing time to discovery : materials and molecular modeling, imaging, informatics, and integration

This work was supported by the KAIST-funded Global Singularity Research Program for 2019 and 2020. J.C.A. acknowledges support from the National Science Foundation under Grant TRIPODS + X:RES-1839234 and the Nano/Human Interfaces Presidential Initiative. S.V.K.’s effort was supported by the U.S. Department of Energy (DOE), Office of Science, Basic Energy Sciences (BES), Materials Sciences and Engineering Division and was performed at the Oak Ridge National Laboratory’s Center for Nanophase Materials Sciences (CNMS), a U.S. Department of Energy, Office of Science User Facility.Multiscale and multimodal imaging of material structures and properties provides solid ground on which materials theory and design can flourish. Recently, KAIST announced 10 flagship research fields, which include KAIST Materials Revolution: Materials and Molecular Modeling, Imaging, Informatics and Integration (M3I3). The M3I3 initiative aims to reduce the time for the discovery, design and development of materials based on elucidating multiscale processing-structure-property relationship and materials hierarchy, which are to be quantified and understood through a combination of machine learning and scientific insights. In this review, we begin by introducing recent progress on related initiatives around the globe, such as the Materials Genome Initiative (U.S.), Materials Informatics (U.S.), the Materials Project (U.S.), the Open Quantum Materials Database (U.S.), Materials Research by Information Integration Initiative (Japan), Novel Materials Discovery (E.U.), the NOMAD repository (E.U.), Materials Scientific Data Sharing Network (China), Vom Materials Zur Innovation (Germany), and Creative Materials Discovery (Korea), and discuss the role of multiscale materials and molecular imaging combined with machine learning in realizing the vision of M3I3. Specifically, microscopies using photons, electrons, and physical probes will be revisited with a focus on the multiscale structural hierarchy, as well as structure-property relationships. Additionally, data mining from the literature combined with machine learning will be shown to be more efficient in finding the future direction of materials structures with improved properties than the classical approach. Examples of materials for applications in energy and information will be reviewed and discussed. A case study on the development of a Ni-Co-Mn cathode materials illustrates M3I3's approach to creating libraries of multiscale structure-property-processing relationships. We end with a future outlook toward recent developments in the field of M3I3.Peer reviewe

Proposing a Simple Radiation Scale for the Public: Radiation Index

A new radiation scale is proposed. With empathy toward the vast majority of people who are not well versed in radiation and related matters, and thus suffering from misunderstanding that breeds unnecessary fear of radiation, the aim of proposing a new radiation scale, radiation index (RAIN), is to put the general public at ease with the concept of radiation. RAIN is defined in dimensionless numbers that relate any specific radiation dose to a properly defined reference level. As RAIN is expressed in plain numbers without an attached scientific unit, the public will feel comfortable with its friendly look, which in turn should help them understand radiation dose levels easily and allay their anxieties about radiation. The expanded awareness and proper understanding of radiation will empower the public to feel that they are not hopeless victims of radiation. The correspondence between RAIN and the specific accumulated dose is established. The equivalence will allow RAIN to serve as a common language of communication for the general public with which they can converse with radiation experts to discuss matters related to radiation safety, radiation diagnosis and therapy, nuclear accidents, and other related matters. Such fruitful dialogues will ultimately enhance public acceptance of radiation and associated technologies

Feasibility study on a stabilization method based on full spectrum reallocation for spectra having non-identical momentum features

Methodology for suppressing or recovering the distorted spectra, which may occur due to mutual non-uniformity and nonlinear response when a multi-detector is simultaneously operated for gamma spectroscopy, is presented with respect to its applicability to stabilization of spectra having the non-identical feature using modified full spectrum reallocation method. The modified full-spectrum reallocation method is extended to provide multiple coefficients that describe the gain drift for multi-division of the spectrum and they were incorporated into an optimization process utilizing a random sampling algorithm. Significant performance improvements were observed with the use of multiple coefficients for solving partial peak dislocation. In this study, our achievements to confirm the stabilization of spectrum having differences in moments and modify the full spectrum reallocation method provide the feasibility of the method and ways to minimize the implication of the non-linear responses normally associated with inherent characteristics of the detector system. We believe that this study will not only simplify the calibration process by using an identical response curve but will also contribute to simplifying data pre-processing for various studies as all spectra can be stabilized with identical channel widths and numbers

An Assessment of the Secondary Neutron Dose in the Passive Scattering Proton Beam Facility of the National Cancer Center

The purpose of this study is to assess the additional neutron effective dose during passive scattering proton therapy. Monte Carlo code (Monte Carlo N-Particle 6) simulation was conducted based on a precise modeling of the National Cancer Center's proton therapy facility. A three-dimensional neutron effective dose profile of the interior of the treatment room was acquired via a computer simulation of the 217.8-MeV proton beam. Measurements were taken with a 3He neutron detector to support the simulation results, which were lower than the simulation results by 16% on average. The secondary photon dose was about 0.8% of the neutron dose. The dominant neutron source was deduced based on flux calculation. The secondary neutron effective dose per proton absorbed dose ranged from 4.942 ± 0.031 mSv/Gy at the end of the field to 0.324 ± 0.006 mSv/Gy at 150 cm in axial distance

Integrated Circuit Design for Radiation-Hardened Charge-Sensitive Amplifier Survived up to 2 Mrad

According to the continuous development of metal-oxide semiconductor (MOS) fabrication technology, transistors have naturally become more radiation-tolerant through steadily decreasing gate-oxide thickness, increasing the tunneling probability between gate-oxide and channel. Unfortunately, despite this radiation-hardened property of developed transistors, the field of nuclear power plants (NPPs) requires even higher radiation hardness levels. Particularly, total ionizing dose (TID) of approximately 1 Mrad could be required for readout circuitry under severe accident conditions with 100 Mrad around a reactor in-core required. In harsh radiating environments such as NPPs, sensors such as micro-pocket-fission detectors (MPFD) would be a promising technology to be operated for detecting neutrons in reactor cores. For those sensors, readout circuits should be fundamentally placed close to sensing devices for minimizing signal interferences and white noise. Therefore, radiation hardening ability is necessary for the circuits under high radiation environments. This paper presents various integrated circuit designs for a radiation hardened charge-sensitive amplifier (CSA) by using SiGe 130 nm and Si 180 nm fabrication processes with different channel widths and transistor types of complementary metal-oxide-semiconductor (CMOS) and bipolar CMOS (BiCMOS). These circuits were tested under γ–ray environment with Cobalt-60 of high level activity: 490 kCi. The experiment results indicate amplitude degradation of 2.85%–34.3%, fall time increase of 201–1730 ns, as well as a signal-to-noise ratio (SNR) of 0.07–11.6 dB decrease with irradiation dose increase. These results can provide design guidelines for radiation hardening operational amplifiers in terms of transistor sizes and structures