1,373 research outputs found
Web Services for forward integration in international tourism supply chains: A case study of tourism in Thailand
International tourism is a highly competitive and information-intensive industry. Customers need volumes of information for decision aids. Moreover, the decision-making processes are quite sensitive to the variables of personal preferences, the tourist industrial ecosystem, the legal regulations and political environments of destinations, the regional or global economic situations, the natural matters, and so on. Hence, the owners of tourism are motivated to upgrade the competitiveness of their businesses with information technologies. This paper intends to design the architecture of Web Services in international tourism, which can contribute to the forward integration in international tourism supply chains. First, the authors conduct an in-depth case study of a regional tour operator in Thailand. In the case study, we examine the strength, weakness, challenges visions, and strategic approaches of international tourism, and their relationships with the information systems in the tourist business. Then, this paper designs the architecture of Web Services in international tourism. The architecture is expected to improve the information transparency through the global tourism supply chain, construct business-to-business collaboration mechanism, provide efficient and effective information to tourists, and consequently contribute to forward integration in international tourism supply chains
Transformer-based Variable-rate Image Compression with Region-of-interest Control
This paper proposes a transformer-based learned image compression system. It
is capable of achieving variable-rate compression with a single model while
supporting the region-of-interest (ROI) functionality. Inspired by prompt
tuning, we introduce prompt generation networks to condition the
transformer-based autoencoder of compression. Our prompt generation networks
generate content-adaptive tokens according to the input image, an ROI mask, and
a rate parameter. The separation of the ROI mask and the rate parameter allows
an intuitive way to achieve variable-rate and ROI coding simultaneously.
Extensive experiments validate the effectiveness of our proposed method and
confirm its superiority over the other competing methods.Comment: Accepted to IEEE ICIP 202
TransTIC: Transferring Transformer-based Image Compression from Human Visualization to Machine Perception
This work aims for transferring a Transformer-based image compression codec
from human vision to machine perception without fine-tuning the codec. We
propose a transferable Transformer-based image compression framework, termed
TransTIC. Inspired by visual prompt tuning, we propose an instance-specific
prompt generator to inject instance-specific prompts to the encoder and
task-specific prompts to the decoder. Extensive experiments show that our
proposed method is capable of transferring the codec to various machine tasks
and outshining the competing methods significantly. To our best knowledge, this
work is the first attempt to utilize prompting on the low-level image
compression task
Adipose-derived mesenchymal stem cells markedly attenuate brain infarct size and improve neurological function in rats
<p>Abstract</p> <p>Background</p> <p>The therapeutic effect of adipose-derived mesenchymal stem cells (ADMSCs) on brain infarction area (BIA) and neurological status in a rat model of acute ischemic stroke (IS) was investigated.</p> <p>Methods</p> <p>Adult male Sprague-Dawley (SD) rats (n = 30) were divided into IS plus intra-venous 1 mL saline (at 0, 12 and 24 h after IS induction) (control group) and IS plus intra-venous ADMSCs (2.0 × 10<sup>6</sup>) (treated interval as controls) (treatment group) after occlusion of distal left internal carotid artery. The rats were sacrificed and brain tissues were harvested on day 21 after the procedure.</p> <p>Results</p> <p>The results showed that BIA was larger in control group than in treatment group (p < 0.001). The sensorimotor functional test (Corner test) identified a higher frequency of turning movement to left in control group than in treatment group (p < 0.05). mRNA expressions of Bax, caspase 3, interleukin (IL)-18, toll-like receptor-4 and plasminogen activator inhibitor-1 were higher, whereas Bcl-2 and IL-8/Gro were lower in control group than in treatment group (all p < 0.05). Western blot demonstrated a lower CXCR4 and stromal-cell derived factor-1 (SDF-1) in control group than in treatment group (all p < 0.01). Immunohistofluorescent staining showed lower expressions of CXCR4, SDF-1, von Willebran factor and doublecortin, whereas the number of apoptotic nuclei on TUNEL assay was higher in control group than in treatment group (all p < 0.001). Immunohistochemical staining showed that cellular proliferation and number of small vessels were lower but glial fibrillary acid protein was higher in control group than in treatment group (all p < 0.01).</p> <p>Conclusions</p> <p>ADMSC therapy significantly limited BIA and improved sensorimotor dysfunction after acute IS.</p
Protection by immunoglobulin dual-affinity retargeting antibodies against dengue virus
Dengue viruses are the most common arthropod-transmitted viral infection, with an estimated 390 million human infections annually and ∼3.6 billion people at risk. Currently, there are no approved vaccines or therapeutics available to control the global dengue virus disease burden. In this study, we demonstrate the binding, neutralizing activity, and therapeutic capacity of a novel bispecific dual-affinity retargeting molecule (DART) that limits infection of all four serotypes of dengue virus
Prevalence of intestinal parasitic infections among school children in capital areas of the Democratic Republic of São Tomé and PrÃncipe, West Africa
Background: Although the Democratic Republic of Sao Tome and Principe (DRSTP) has undertaken school children-based deworming programs against intestinal parasitic infections (IPIs) using a single dose of mebendazole annually since 2005, it remains unclear as to the outcome to date. The present study intends to investigate the recent IPIs status among school children living in capital areas of the DRSTP.Methods: A total of 252 school children (121 boys and 131 girls) of grades 4 and 5 from 4 primary schools located in the capital areas participated in the present study and their fresh fecal specimens were examined for the presence of any parasites using the merthiolate- iodine-formaldehyde concentration method as conducted.Results: The overall prevalence of IPIs was 64.7% (163/ 252). No significant gender difference in prevalence between boys (67.8%) and girls (61.8%) was found (p = 0.3). The majority of school children were infected with a single species of parasite (55.8%). Altogether, 12 different intestinal parasite species were identified in DRSTP school children, of which 9 species were pathogenic and the remaining 3 were non-pathogenic.Conclusion: Improving the detection method, sanitation facilities and personal hygiene as well as utilizing combined drugs are all important measures to greatly reduce IPIs in DRSTP school children.Keywords: Democratic Republic of Sao Tome and Principe, school children, intestinal parasitic infection
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