1,635 research outputs found

    Improved Antireflection Properties of an Optical Film Surface with Mixing Conical Subwavelength Structures

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    Based on finite difference time domain method, an optical film surface with mixing conical subwavelength structures is numerically investigated to improve antireflection property. The mixing conical subwavelength structure is combined with the pure periodic conical subwavelength structures and the added small conical structures in the gap between the pure periodic conical subwavelength structures. The antireflection properties of two types of subwavelength structures with different aspect ratios in spectral range of 400–800 nm are analyzed and compared. It is shown that, for the mixing type, the average reflectance is decreased and the variances of the reflectance are evidently smaller. When the added structure with a better aspect ratio exists, the average reflectance of the surface can be below 0.30%. Obviously, the antireflection properties of the optical film surface with mixing conical subwavelength structures can be improved

    N,N′-Bis(6-methyl-2-pyrid­yl)oxamide

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    In the crystal structure of the title compound, C14H14N4O2, the mol­ecules are almost planar (mean deviation 0.028 Å) and a weak intra­molecular N—H⋯O hydrogen bond between the H atom bound to an oxamide N atom and a carbonyl O atom is found. The asymmetric unit consits of one half-mol­ecule which is located on a centre of inversion

    Assessing the Integrity of Spillway Foundations

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    The erosion under a spillway can be a long-term issue that threatens the structural integrity of a water reservoir. The spillway under investigation was suspected to be defective after it had been commissioned in 1987 (Figure 1). Potholes and subsurface cavities were confirmed in the safety assessment using various NDT techniques including ground penetrating radar and impact echo. The GPR inspection was able to differentiate the intact region from the cavities under concrete slabs (Figure 2). The impact echo results and associated analyses provided further evidence of inferior condition in the soil under the concrete slabs. The engineering team designed and executed the repair project based on the conclusion of the integrity assessment. Subsequent GPR inspection has been performed so as to monitor the integrity of the spillway in a period of 18 months following the repair

    The Third Stage Management Project of Climate Change Impacts and Adaptation on Water Environment (2/5)

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    Source: ICHE Conference Archive - https://mdi-de.baw.de/icheArchive

    6,6′-Dimethyl-2,2′-[oxalylbis(aza­nedi­yl)]dipyridinium dichloride acetonitrile solvate

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    In the crystal structure of the title compound, C14H16N4O2 2+·2Cl−·CH3CN, weak inter­molecular N—H⋯Cl hydrogen bonds are found between the H atoms bound to the pyridine and amine N atoms and the chloride anions. The asymmetric unit consits of one half cationic mol­ecule which is located on a centre of inversion, one chloride anion in a general position and one half acetonitrile mol­ecule which is located on a twofold axis. Because of symmetry, the C—H hydrogens of the acetonitrile solvent mol­ecule are disordered over two orientations

    Identification of overexpressed cytokines as serum biomarkers of hepatitis C virus-induced liver fibrosis using bead-based flexible multiple analyte profiling

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    Hepatic inflammation is the stimulator to activate hepatic stellate cells (HSCs) and triggers fibrogenesis. Cytokines are produced during liver inflammation and maybe considered as liver fibrosis biomarker. The aim of this study was to investigate whether cytokines can be used as reliable biomarkers of liver fibrosis using flexible multi-analyte profiling (xMAP). A total of 61 chronic hepatitis C patients with different severity of liver fibrosis were enrolled. Liver biopsy was used as standard to assess the severity of fibrosis according to METAVIR classification. Afterward, 15 samples from healthy controls were analyzed and totally 50 cytokines were screened using flexible multi-analyte profiling to discover differential biomarkers. Finally, levels of protein expressions of individual stages of liver fibrosis were measured. In histological examination, the necroinflammatory score (histology activity index, HAI) was increased from F1 to F4 stage in hepatitis C virus (HCV) infected patients, indicating that inflammation was accompanied with the progression of liver fibrosis. Using flexible multi-analyte profiling, four serum cytokines, including IFN-α2 (p=0.023), GRO-α (p=0.013), SCF (p=0.047) and SDF-1α p=0.024), were identified under antibody specific recognition and elevated with HAI score. This study reveals the relationship between cytokines and liver fibrosis, and demonstrated that IFN-α2, GRO-α, SCF and SDF-1 α may be used as biomarkers to predict liver fibrosis. The overexpressed cytokines may play a role in the progression of liver fibrosis and deserves further investigation.Keywords: Cytokine, flexible multi-analyte profiling, hepatitis C virus, liver fibrosisAfrican Journal of Biotechnology Vol. 11(29), pp. 7535-7541, 29 April, 201
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