255 research outputs found

    AN ECONOMY-WIDE ANALYSIS OF GM FOOD LABELING POLICIES IN TAIWAN

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    The development of agricultural biotechnology offers the opportunity to increase crop production, lowers farming costs, improves food quality and could reduce costs to consumers. For the food importing economies, the import quantities as well as prices will be affected through world market as the production technology of GM crops is adopted by the exporting countries. Many sectors will be affected by the use of these crops through vertical (or backward) and horizontal (or forward) linkages. The purpose of this paper is to develop an economy-wide quantitative assessment of the economic impacts of the introduction of GM products with and without labeling. The modeling framework used in this analysis is TAIGEM (Taiwan General Equilibrium Model), a multi-sectoral computable general equilibrium (CGE) model of the Taiwan¡¦s economy which is derived from ORANI model (Dixon, Parmenter, Sutton and Vincent, 1982). TAIGEM is amended by splitting corn and soybeans into GM and non-GM varieties. It also endogenizes the decision of producers and consumers to use GM vs. non-GM corn and soybeans in their intermediate uses and consumption, respectively. We also consider the consumers¡¦ acceptance of GM food so that the mandatory labeling policy can be examined. Our simulation results indicate that the most extreme import ban on GM crops would be very costly in terms of total production values, ranging from NT$ 40 to 90 billions per year.Research and Development/Tech Change/Emerging Technologies,

    Poly[bis­(μ2-4,4′-bipyridine)bis­(3-nitro­benzoato)cobalt(II)]

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    The hydro­thermal reaction of cobalt nitrate with 4,4′-bipyridine and 3-nitro­benzoic acid lead to the formation of the title complex, [Co(C7H4NO4)2(C10H8N2)2]n. In the crystal structure, the CoII atoms are coordinated by two terminal carboxyl­ate anions and four 4,4′-bipyridine ligands within slightly distorted octa­hedra. The CoII atom and one of the two independent 4,4′-bipyridine ligands are located on a twofold rotation axis, while the second independent 4,4′-bipyridine mol­ecule is located on a centre of inversion. One of the two rings of one 4,4′-bipyridine ligand is disordered over two orientations and was refined using a split model [occupancy ratio 0.68 (2):0.32 (2)]. The CoII atoms are connected by the 4,4′-bipyridine ligands into layers, which are located parallel to the ab plane

    catena-Poly[[tetraaquanickel(II)]-μ3-benzene-1,3,5-tricarboxylato-3′:1:2-κ4 O 1:O 3,O 3′:O 5-[tetraaquanickel(II)]-μ2-benzene-1,3,5-tricarboxylato-2:3κ2 O 1:O 3-[tetraaquanickel(II)]]

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    The microwave solvothermal reaction of nickel nitrate with trimesic acid provided the title compound, [Ni3(BTC)2(H2O)12]n (BTC = benzene-1,3,5-tricarboxyl­ate anion, C9H3O6), which is a metal coordination polymer composed of one-dimensional zigzag chains. The crystal under investigation was ramecically twinned with an approximate twin domain ratio of 1:1. In the asymmetric unit, there are two types of Ni atoms. One of the NiO6 groups (2 symmetry) is coordinated to only one carboxyl­ate group and thus terminal, the other is bridging, forming the coordination polymer. The extended chains are connected by the organic BTC anions via μ 2-linkages. O—H⋯O hydrogen bonds and π–π inter­actions between the chains [centroid–centroid distance 3.58 (1) Å] induce the complex to mimic a three-dimensional structure

    In Situ Confocal Raman Mapping Study of a Single Ti-Assisted ZnO Nanowire

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    In this work, we succeeded in preparing in-plane zinc oxide nanowires using a Ti-grid assisted by the chemical vapor deposition method. Optical spatial mapping of the Confocal Raman spectra was used to investigate the phonon and geometric properties of a single ZnO nanowire. The local optical results reveal a red shift in the non-polar E2 high frequency mode and width broadening along the growth direction, reflecting quantum-confinement in the radial direction

    Serum repressing efflux pump CDR1 in Candida albicans

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    BACKGROUND: In the past decades, the prevalence of candidemia has increased significantly and drug resistance has also become a pressing problem. Overexpression of CDR1, an efflux pump, has been proposed as a major mechanism contributing to the drug resistance in Candida albicans. It has been demonstrated that biological fluids such as human serum can have profound effects on antifungal pharmacodynamics. The aim of this study is to understand the effects of serum in drug susceptibility via monitoring the activity of CDR1 promoter of C. albicans. RESULTS: The wild-type C. albicans cells (SC5314) but not the cdr1/cdr1 mutant cells became more susceptible to the antifungal drug when the medium contained serum. To understand the regulation of CDR1 in the presence of serum, we have constructed CDR1 promoter-Renilla luciferase (CDR1p-RLUC) reporter to monitor the activity of the CDR1 promoter in C. albicans. As expected, the expression of CDR1p-RLUC was induced by miconazole. Surprisingly, it was repressed by serum. Consistently, the level of CDR1 mRNA was also reduced in the presence of serum but not N-acetyl-D-glucosamine, a known inducer for germ tube formation. CONCLUSION: Our finding that the expression of CDR1 is repressed by serum raises the question as to how does CDR1 contribute to the drug resistance in C. albicans causing candidemia. This also suggests that it is important to re-assess the prediction of in vivo therapeutic outcome of candidemia based on the results of standard in vitro antifungal susceptibility testing, conducted in the absence of serum

    Multimillijoule sub-optical-cycle parametric waveform synthesis for attosecond science

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    We present a phase-stable, multi-mJ 3-channelparametric synthesizer generating 2-octave-wide waveforms (0.52-2.4 ÎĽm). After two amplification stages, the combined 125-ÎĽJ output supports 1.9-fs waveforms. The energy is scaled to 2 mJ after three amplification stages

    High-energy sub-cycle optical waveform synthesizer

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    High-energy sub-cycle optical waveform synthesis is demonstrated with a three-channel OPA pumped by an 18-mJ cryogenically cooled Ti:sapphire laser. The system aims towards multi-mJ, 2-fs, phase-stable pulses covering the wavelength range from 0.52 - 2.4ÎĽ

    Toward Waveform Nonlinear Optics Using Multimillijoule Sub-Cycle Waveform Synthesizers

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    Waveform nonlinear optics aims to study and control the nonlinear interactions of matter with extremely short optical waveforms custom-tailored within a single cycle of light. Different technological routes to generate such multimillijoule sub-optical-cycle waveforms are currently pursued, opening up unprecedented opportunities in attoscience and strong-field physics. Here, we discuss the experimental schemes, introduce the technological challenges, and present our experimental results on high-energy sub-cycle optical waveform synthesis based on (1) parametric amplification and (2) induced-phase modulation in a two-color-driven gas-filled hollow-core fiber compressor. More specifically, for (1), we demonstrate a carrier-envelope-phase (CEP)-stable, multimillijoule three-channel parametric waveform synthesizer generating a >2-octave-wide spectrum (0.52-2.4 ÎĽm). After two amplification stages, the combined 125-ÎĽJ output supports 1.9-fs FWHM waveforms; energy scaling to >2 mJ is achieved after three amplification stages. FROG pulse characterization of all three second-stage outputs demonstrates the feasibility to recompress all three channels simultaneously close to the Fourier limit and shows the flexibility of our intricate dispersion management scheme for different experimental situations. For (2), we generate CEP-stable 1.7-mJ waveforms covering 365-930 nm (measured at 1% of the peak intensity) obtained from induced-phase modulation in a two-color-driven gas-filled hollow-core fiber. Using custom-designed double-chirped mirrors and a UV spatial light modulator will permit compression close to the 0.9-fs FWHM transform limit. These novel sources will become versatile tools for controlling strong-field interactions in matter and for attosecond pump-probe spectroscopy using VIS/IR and XUV/soft-X-ray pulses

    Effect of membrane fusion protein AdeT1 on the antimicrobial resistance of Escherichia coli

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    Acinetobacter baumannii is a prevalent pathogen that can rapidly acquire resistance to antibiotics. Indeed, multidrug-resistant A. baumannii is a major cause of hospital-acquired infections and has been recognised by the World Health Organization as one of the most threatening bacteria to our society. Resistance-nodulation-division (RND) type multidrug efflux pumps have been demonstrated to convey antibiotic resistance to a wide range of pathogens and are the primary resistance mechanism employed by A. baumannii. A component of an RND pump in A. baumannii, AdeT1, was previously demonstrated to enhance the antimicrobial resistance of Escherichia coli. Here, we report the results of experiments which demonstrate that wild-type AdeT1 does not confer antimicrobial resistance in E. coli, highlighting the importance of verifying protein production when determining minimum inhibitory concentrations (MICs) especially by broth dilution. Nevertheless, using an agar-based MIC assay, we found that propionylation of Lys280 on AdeT1 renders E. coli cells more resistant to erythromycin

    Gendered factors associated with preventive behaviors and mental health among Chinese adults during the COVID-19 pandemic home quarantine

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    The outbreak of the coronavirus disease in 2019 (COVID-19) has greatly impacted the life and mental health of many people globally. The objective of this study was to investigate the factors associated with preventive behaviors and mental health among Chinese adults during their home quarantine in the COVID-19 period. An online questionnaire survey was administered in March 2020. The study participants were adults aged between 18 and 70 years old from 31 provinces in China. Of the 3878 participants, 1314 reported moderate levels of anxiety, and the remaining participants reported moderate to severe levels of anxiety. Findings revealed that females aged between 18 and 30 years old who had higher educational qualifications, greater levels of preventive knowledge, trust in the government, and resided in urban and medium-risk areas (R2 = 0.100, F = 27.97, p < 0.001) were more likely to exhibit preventive behaviors. In contrast, a higher negative emotional response was generally seen in males who had low levels of preventive knowledge and behaviors, higher risk perception of infection, lower trust in the government, and unhealthy lifestyles (R2 = 0.127, F = 32.33, p < 0.001). In addition, the high-risk perception of infection was positively associated with high odds of anxiety (AOR = 1.17, 95% CI: 1.10–1.24), whereas a greater level of preventive knowledge (AOR = 0.36, 95% CI: 0.19–0.70) and behaviors (AOR = 0.69, 95% CI: 0.57–0.84), higher trust in the government’s COVID-19 pandemic mitigation measures (AOR = 0.77, 95% CI: 0.71–0.83), and a healthier lifestyle (AOR = 0.89, 95% CI: 0.79–0.99) were negatively associated with high odds of anxiety. Results showed that a lower level of anxiety and negative emotional response were associated with better preventive behaviors against COVID-19, which were influenced by preventive knowledge, risk perception, trust in the government’s COVID-19 pandemic mitigation measures, and healthy lifestyle. Findings in this study could help formulate health interventions for vulnerable groups related to gendered vulnerabilities in the COVID-19 environment to improve their mental health and preventive behaviors, especially during the period of a pandemic
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