2,455 research outputs found
Probing gravitational non-minimal coupling with dark energy surveys
We investigate observational constraints on a specific one-parameter
extension to the minimal quintessence model, where the quintessence field
acquires a quadratic coupling to the scalar curvature through a coupling
constant . The value of is highly suppressed in typical tracker
models if the late-time cosmic acceleration is driven at some field values near
the Planck scale. We test in a second class of models in which the field
value today becomes a free model parameter. We use the combined data from
type-Ia supernovae, cosmic microwave background, baryon acoustic oscillations
and matter power spectrum, to weak lensing measurements and find a best-fit
value where is excluded outside the 95 per cent
confidence region. The effective gravitational constant subject
to the hint of a non-zero is constrained to at the same confidence level on cosmological scales, and can be narrowed
down to when combining with Solar
System tests.Comment: Context extended, figures and references added, title changed to
match with accepted version for publicatio
"Teleparallel" Dark Energy
Using the "teleparallel" equivalent of General Relativity as the
gravitational sector, which is based on torsion instead of curvature, we add a
canonical scalar field, allowing for a nonminimal coupling with gravity.
Although the minimal case is completely equivalent to standard quintessence,
the nonminimal scenario has a richer structure, exhibiting quintessence-like or
phantom-like behavior, or experiencing the phantom-divide crossing. The richer
structure is manifested in the absence of a conformal transformation to an
equivalent minimally-coupled model.Comment: 5 pages, 1 figure, Version published in PLB704 (2011) 384-38
Theory of starch biosynthesis and their structures for the rational design of starches: a mathematical modelling approach
Shape restricted regression with random Bernstein polynomials
Shape restricted regressions, including isotonic regression and concave
regression as special cases, are studied using priors on Bernstein polynomials
and Markov chain Monte Carlo methods. These priors have large supports, select
only smooth functions, can easily incorporate geometric information into the
prior, and can be generated without computational difficulty. Algorithms
generating priors and posteriors are proposed, and simulation studies are
conducted to illustrate the performance of this approach. Comparisons with the
density-regression method of Dette et al. (2006) are included.Comment: Published at http://dx.doi.org/10.1214/074921707000000157 in the IMS
Lecture Notes Monograph Series
(http://www.imstat.org/publications/lecnotes.htm) by the Institute of
Mathematical Statistics (http://www.imstat.org
Disordered Fe vacancies and superconductivity in potassium-intercalated iron selenide (K2-xFe4+ySe5)
The parent compound of an unconventional superconductor must contain unusual
correlated electronic and magnetic properties of its own. In the high-Tc
potassium intercalated FeSe, there has been significant debate regarding what
the exact parent compound is. Our studies unambiguously show that the
Fe-vacancy ordered K2Fe4Se5 is the magnetic, Mott insulating parent compound of
the superconducting state. Non-superconducting K2Fe4Se5 becomes a
superconductor after high temperature annealing, and the overall picture
indicates that superconductivity in K2-xFe4+ySe5 originates from the Fe-vacancy
order to disorder transition. Thus, the long pending question whether magnetic
and superconducting state are competing or cooperating for cuprate
superconductors may also apply to the Fe-chalcogenide superconductors. It is
believed that the iron selenides and related compounds will provide essential
information to understand the origin of superconductivity in the iron-based
superconductors, and possibly to the superconducting cuprates
Serial increase of IL-12 response and human leukocyte antigen-DR expression in severe sepsis survivors
Introduction: Sepsis-induced immunosuppression may result in death. The mechanisms of immune suppression include loss of macrophage and monocyte expression of the major histocompatibility complex, increased anti-inflammatory cytokine expression and decreased expression of proinflammatory cytokines. In this study, we sought to determine the mechanisms of immune suppression in severe sepsis by repeated detection. Methods: We designed this prospective observational study to measure monocyte human leukocyte antigen (HLA)-DR expression, plasma cytokine levels and cytokine responses on days 1 and 7 in stimulated peripheral blood mononuclear cells (PBMCs) of healthy controls and patients with severe sepsis. Results: Of the 35 enrolled patients, 23 survived for 28 days and 12 died, 6 of whom died within 7 days. Plasma levels of IL-1 beta, IL-6, IL-10, IL-17, transforming growth factor (TGF)-beta 1 and TNF-alpha were higher, but plasma IL-12 level was lower in septic patients than those in controls. Day 1 plasma levels of IL-1 beta, IL-6, IL-10 and TGF-beta 1 in nonsurvivors were higher than those in survivors. Day 7 plasma IL-10 levels in nonsurvivors were higher than in survivors. IL-1 beta response was higher, but IL-12 and TNF-alpha responses were lower in septic patients than in controls. Day 1 IL-6 response was lower, but day 1 TGF-beta 1 response was higher in nonsurvivors than in survivors. Plasma IL-6 and IL-10 levels were decreased in survivors after 6 days. IL-6 response was decreased in survivors after 6 days, but IL-12 response was increased. Monocyte percentage was higher, but positive HLA-DR percentage in monocytes and mean fluorescence intensity (MFI) of HLA-DR were lower in septic patients than in controls. MFI of HLA-DR was increased in survivors after 6 days. Conclusions: Monocyte HLA-DR expression and IL-12 response from PBMCs are restored in patients who survive severe sepsis
Profiling time course expression of virus genes---an illustration of Bayesian inference under shape restrictions
There have been several studies of the genome-wide temporal transcriptional
program of viruses, based on microarray experiments, which are generally useful
in the construction of gene regulation network. It seems that biological
interpretations in these studies are directly based on the normalized data and
some crude statistics, which provide rough estimates of limited features of the
profile and may incur biases. This paper introduces a hierarchical Bayesian
shape restricted regression method for making inference on the time course
expression of virus genes. Estimates of many salient features of the expression
profile like onset time, inflection point, maximum value, time to maximum
value, area under curve, etc. can be obtained immediately by this method.
Applying this method to a baculovirus microarray time course expression data
set, we indicate that many biological questions can be formulated
quantitatively and we are able to offer insights into the baculovirus biology.Comment: Published in at http://dx.doi.org/10.1214/09-AOAS258 the Annals of
Applied Statistics (http://www.imstat.org/aoas/) by the Institute of
Mathematical Statistics (http://www.imstat.org
Commensurate lock-in and incommensurate supersolid phases of hardcore bosons on anisotropic triangular lattices
We investigate the interplay between commensurate lock-in and incommensurate
supersolid phases of the hardcore bosons at half-filling with anisotropic
nearest-neighbor hopping and repulsive interactions on triangular lattice. We
use numerical quantum and variational Monte Carlo as well as analytical
Schwinger boson mean-field analysis to establish the ground states and phase
diagram. It is shown that, for finite size systems, there exist a series of
jumps between different supersolid phases as the anisotropy parameter is
changed. The density ordering wavevectors are locked to commensurate values and
jump between adjacent supersolids. In the thermodynamic limit, however, the
magnitude of these jumps vanishes leading to a continuous set of novel
incommensurate supersoild phases.Comment: 5 pages, 5 figures, added new results, changed title and conclusio
- …