76 research outputs found
Big data analytics and environmental performance: The moderating role of internationalization
This study investigates the influence of big data analytics on environmental performance in the context of US Fortune 500 listed internationalizing companies from 2010 to 2021. Grounded in organizational learning theory, our results highlight BDA's positive impact, enabling firms to adapt and enhance environmental practices through data-driven insights. Furthermore, the study reveals the moderating role of internationalization, emphasizing the strategic management of knowledge and engagement with diverse stakeholders as pivotal factors in enhancing the positive influence of BDA on environmental performance. These findings offer valuable insights for organizations leveraging data analytics to address environmental challenges in the global business landscape
Enhancing functional production of a chaperone-dependent lipase in Escherichia coli using the dual expression cassette plasmid
IMPLEMENT POLICIES ON TRAINING AND FOSTERING CADRES AND CIVIL SERVANTS OF KHMER IN THE MEKONG DELTA, VIETNAM
Cadres and civil servants who are ethnic Khmer people in the Mekong Delta have an essential position and role in implementing the Party's guidelines and guidelines, policies, and laws of the State to present with the people and directly manage society to achieve order, stability, and development. Cadres and civil servants who are ethnic Khmer people are the bridge between the Party, State, and the people, reflecting the people's legitimate thoughts and aspirations for the Party and State. Based on the method of document research, and secondary data, the paper outlines the characteristics of the Khmer people in the Mekong Delta; viewpoints and lines of the Party, policies, and laws of the State on training and retraining policies for cadres and civil servants who are ethnic Khmer people; On the basis of the actual situation of the policy, the thesis has proposed a number of solutions to improve the effectiveness of the policy on training and fostering cadres and civil servants who are ethnic Khmer people in the Mekong Delta. Article visualizations
USING EXPERIMENTAL PLANNING TO OPTIMIZE THE HYDROLYSIS OF SUGAR CANE BAGASSE INTO FERMENTABLE SUGARS FOR BIOETHANOL PRODUCTION BY FUNGAL ENZYME MIXTURE
In this study, the unpretreated sugar cane bagasse was milled to a particle size of 0.5 – 1 mm and be used as material for bioconversion into fermentable sugars by using an enzyme cocktail acted synergistically. Experimental planning was used to optimize the enzyme conversion through assessment and analysis of individual parameter. As the result, the optimal condition for enzymatic conversion of sugar cane bagasse into reducing sugar product are at pH = 5, 400C, and 48 h incubation in rate of enzyme (Cell/Xyl, AltFAE, XpoAE) and substrate (bagasse meal) is 3.1. From the above application, the mathematical model is found to describe equation of the bioconversion of bagasse into reducing sugars: = 206.946 + 29.954x1 + 5.501x2 + 7.323x3 + 2.288x2x3 – 7.011; and using flexible algorithm of nonlinear planning to identify optimal conditions of enzyme mixture of conversion into reducing sugars that the reaction reached max = 251.86 mg per gram bagasse with x1 = 1.215, x2 = 1.215, x3 = 1.215 or Cell/Xyl = 1 ml (100U), AltFAE = 0.5 ml (7.56U), XpoAE = 0.4 ml (10.8U) on the test range. Experimental verification has the same result in constant conditons and reached total reducing sugars of 260.2 mg per gram substrate.In this study, the unpretreated sugar cane bagasse was milled to a particle size of 0.5 – 1 mm and be used as material for bioconversion into fermentable sugars by using an enzyme cocktail acted synergistically. Experimental planning was used to optimize the enzyme conversion through assessment and analysis of individual parameter. As the result, the optimal condition for enzymatic conversion of sugar cane bagasse into reducing sugar product are at pH = 5, 40 oC, and 48 h incubation in rate of enzyme (Cell/Xyl, AltFAE, XpoAE) and substrate (bagasse meal) is 3.1. From the above application, the mathematical model is found to describe equation of the bioconversion of bagasse into reducing sugars: = 206.946 + 29.954x1 + 5.501x2 + 7.323x3 + 2.288x2x3 – 7.011; and using flexible algorithm of nonlinear planning to identify optimal conditions of enzyme mixture of conversion into reducing sugars that the reaction reached max = 251.86 mg per gram bagasse with x1 = 1.215, x2 = 1.215, x3 = 1.215 or Cell/Xyl = 1 ml (100U), AltFAE = 0.5 ml (7.56U), XpoAE = 0.4 ml (10.8U) on the test range. Experimental verification has the same result in constant conditons and reached total reducing sugars of 260.2 mg per gram substrate
EVALUATION OF CITIZENS' SATISFACTION WITH THE QUALITY OF PUBLIC ADMINISTRATIVE SERVICES IN THE MEKONG DELTA, VIETNAM
Citizen satisfaction is one of the essential factors reflecting the quality of public administrative services provided by
state administrative agencies. The study aims to assess citizens' satisfaction with the quality of public administrative services in
the Mekong Delta, Vietnam. Research data were collected from survey results using questionnaires from 792 survey samples in
the Mekong Delta, Vietnam. Research results have shown that citizens are satisfied with the quality of public administrative services
in the Mekong Delta, Vietnam. At the same time, there are six factors affecting citizens' satisfaction with the quality of public
administrative services, including (1) Reliability; (2) Service capacity of staff; (3) Service attitude of staff; (4) The service level of
staff; (5) Infrastructure; (6) Administrative procedures. Research results show no difference in citizen satisfaction in gender, age
and education groups. Besides, the survey area group has a difference in citizen satisfaction. The research results have theoretical
and practical significance for public administration in Vietnam. From the research results, several contents are discussed and
proposed to improve citizens' satisfaction with the quality of public administrative services in the Mekong Delta, Vietnam
Visualization of Strain-Induced Landau Levels in a Graphene - Black Phosphorus Heterostructure
Strain-induced pseudo magnetic fields offer the possibility of realizing zero
magnetic field Quantum Hall effect in graphene, possibly up to room
temperature, representing a promising avenue for lossless charge transport
applications. Strain engineering on graphene has been achieved via random
nanobubbles or artificial nanostructures on the substrate, but the highly
localized and non-uniform pseudomagnetic fields can make spectroscopic probes
of electronic structure difficult. Heterostructure engineering offers an
alternative approach: By stacking graphene on top of another van der Waals
material with large lattice mismatch at a desired twist angle, it is possible
to generate large strain-induced pseudo magnetic fields uniformly over the
entire heterostructure. Here, we report using nano-angle resolved photoemission
spectroscopy (nano-ARPES) to probe the electronic bandstructure of a
graphene/black phosphorus heterostructure (G/BP). By directly measuring the
iso-energy contours of graphene and black phosphorus we determine a twist angle
of 20-degrees in our heterostructure. High-resolution nano-ARPES of the
graphene bands near the Fermi level reveals the emergence of flat bands located
within the Dirac cone. The spacing of the flat bands is consistent with Landau
level formation in graphene, and corresponds to a pseudo-field of 11.36 T. Our
work provides a new way to study quantum Hall phases induced by strain in 2D
materials and heterostructures
Estimating the cost of illness of acute Japanese encephalitis and sequelae care in Vietnam and Laos: a cross-sectional study
Background
Japanese encephalitis (JE) is a leading cause of acute encephalitis syndrome and resulting neurological disability in Asia and the Western Pacific. This study aims to estimate the cost of acute care, initial rehabilitation and sequelae care, in Vietnam and Laos.
Methodology
We conducted a cross-sectional retrospective study using a micro-costing approach from the health system and household perspectives. Out-of-pocket direct medical and non-medical costs, indirect costs, and family impact were reported by patients and/or caregivers. Hospitalization costs were extracted from hospital charts. Acute costs covered expenditures from pre-hospital to follow-up visits while sequelae care costs were estimated from expenditures in the last 90 days. All costs are in 2021 US dollars.
Principal findings
242 patients in two major sentinel sites in the North and South of Vietnam and 65 patients in a central hospital in Vientiane, Laos, with laboratory-confirmed JE were recruited regardless of age, sex, and ethnicity. In Vietnam, the mean total cost was 2,071, standard error [SE] 404 for initial sequelae care (median 220) and 0, SE 2,005 (median 279) and the mean annual costs were 0, SE 89 (median 57) for long-term sequelae care. In both countries, most patients did not seek care for their sequelae. Families perceived extreme impact from JE and 20% to 30% of households still had sustained debts years after acute JE.
Conclusions
JE patients and families in Vietnam and Laos suffer extreme medical, economic, and social hardship. This has policy implications for improving JE prevention in these two JE-endemic countries
Adaptive immune response to lipoproteins of Staphylococcus aureus in healthy subjects
Staphylococcus aureus is a frequent commensal but also a dangerous pathogen, causing many forms of infection ranging from mild to life-threatening conditions. Among its virulence factors are lipoproteins, which are anchored in the bacterial cell membrane. Lipoproteins perform various functions in colonization, immune evasion, and immunomodulation. These proteins are potent activators of innate immune receptors termed Toll-like receptors 2 and 6. This study addressed the specific B-cell and T-cell responses directed to lipoproteins in human S. aureus carriers and non-carriers. 2D immune proteomics and ELISA approaches revealed that titers of antibodies (IgG) binding to S. aureus lipoproteins were very low. Proliferation assays and cytokine profiling data showed only subtle responses of T cells; some lipoproteins did not elicit proliferation. Hence, the robust activation of the innate immune system by S. aureus lipoproteins does not translate into a strong adaptive immune response. Reasons for this may include inaccessibility of lipoproteins for B cells as well as ineffective processing and presentation of the antigens to T cells.</p
A novel IGHMBP2 variant and clinical diversity in Vietnamese SMARD1 and CMT2S patients
BackgroundPathogenic variants in the IGHMBP2 gene are associated with two distinct autosomal recessive neuromuscular disorders: spinal muscular atrophy with respiratory distress type 1 (SMARD1; OMIM #604320) and Charcot–Marie–Tooth type 2S (CMT2S; OMIM #616155). SMARD1 is a severe and fatal condition characterized by infantile-onset respiratory distress, diaphragmatic palsy, and distal muscular weakness, while CMT2S follows a milder clinical course, with slowly progressive distal muscle weakness and sensory loss, without manifestations of respiratory disorder.MethodsWhole-exome sequencing of the IGHMBP2 gene was performed for eight Vietnamese patients with IGHMBP2-related neuromuscular disorders including five patients with SMARD1 and the others with CMT2S.ResultsWe identified one novel IGHMBP2 variant c.1574T > C (p.Leu525Pro) in a SMARD1 patient. Besides that, two patients shared the same pathogenic variants (c.1235 + 3A > G/c.1334A > C) but presented completely different clinical courses: one with SMARD1 who deceased at 8 months of age, the other with CMT2S was alive at 3 years old without any respiratory distress.ConclusionThis study is the first to report IGHMBP-2-related neuromuscular disorders in Vietnam. A novel IGHMBP2 variant c.1574T > C (p.Leu525Pro) expressing SMARD1 phenotype was detected. The presence of three patients with the same genotype but distinct clinical outcomes suggested the interaction of variants and other factors including relating modified genes in the mechanism of various phenotypes
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