FUNCTION AND REGULATION OF CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IN THE ATTENUATION OF PAIN IN MICE

Ph.DDOCTOR OF PHILOSOPH

Sufficiency of the Central Provident Fund in meeting healthcare and retirement needs : a comparison with selected countries.

This paper aims to ascertain the adequacy of Singapore’s Central Provident Fund in providing for the healthcare and retirement needs of Singaporeans by comparing it with schemes in other countries. Through this, we hope to get a better picture of the robustness of the current CPF system, and generate practical recommendations to improve it

Pleotropic Roles of Autotaxin in the Nervous System Present Opportunities for the Development of Novel Therapeutics for Neurological Diseases

10.1007/s12035-019-01719-1MOLECULAR NEUROBIOLOGY571372-39

Complete chloroplast genome data of Shorea macrophylla (Engkabang): Structural features, comparative and phylogenetic analysis

Shorea macrophylla belongs to the Shorea genus under the Dipterocarpaceae family. It is a woody tree that grows in the rainforest in Southeast Asia. The complete chloroplast (cp) genome sequence of S. macrophylla is reported here. The genomic size of S. macrophylla is 150,778 bp and it possesses a circular structure with conserved constitute regions of large single copy (LSC, 83,681 bp) and small single copy (SSC, 19,813 bp) regions, as well as a pair of inverted repeats with a length of 23,642 bp. It has 112 unique genes, including 78 protein-coding genes, 30 tRNA genes, and four rRNA genes. The genome exhibits a similar GC content, gene order, structure, and codon usage when compared to previously reported chloroplast genomes from other plant species. The chloroplast genome of S. macrophylla contained 262 SSRs, the most prevalent of which was A/T, followed by AAT/ATT. Furthermore, the sequences contain 43 long repeat sequences, practically most of them are forward or palindrome type long repeats. The genome structure of S. macrophylla was compared to the genomic structures of closely related species from the same family, and eight mutational hotspots were discovered. The phylogenetic analysis demonstrated a close relationship between Shorea and Parashorea species, indicating that Shorea is not monophyletic. The complete chloroplast genome sequence analysis of S. macrophylla reported in this paper will contribute to further studies in molecular identification, genetic diversity, and phylogenetic research

Biological Effects of Naturally Occurring Sphingolipids, Uncommon Variants, and Their Analogs

10.1007/s12017-016-8424-8NEUROMOLECULAR MEDICINE183396-414United State

Sphingolipidomics analysis of large clinical cohorts. Part 1: Technical notes and practical considerations

10.1016/j.bbrc.2018.04.076BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS5043596-60

Sphingolipidomics analysis of large clinical cohorts. Part 2: Potential impact and applications

10.1016/j.bbrc.2018.04.075BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS5043602-60

ROLE OF PREFRONTAL CORTICAL CALCIUM-INDEPENDENT PHOSPHOLIPASE A(2) IN ANTINOCICEPTIVE EFFECT OF THE NOREPINEPHRINE REUPTAKE INHIBITOR ANTIDEPRESSSANT MAPROTILINE

10.1016/j.neuroscience.2016.10.037NEUROSCIENCE34091-10

Dietary fat and protein intake in relation to plasma sphingolipids as determined by a large-scale lipidomic analysis

10.3390/metabo11020093Metabolites1121-1