31 research outputs found
A Pontine Region is a Neural Correlate of the Human Affective Processing Network
The in vivo neural activity of the pons during the perception of affective stimuli has not been studied despite the strong implications of its role in affective processing. To examine the activity of the pons during the viewing of affective stimuli, and to verify its functional and structural connectivity with other affective neural correlates, a multimodal magnetic resonance imaging methodology was employed in this study. We observed the in vivo activity of the pons when viewing affective stimuli. Furthermore, small-world connectivity indicated that the functional connectivity (FC) between the pons and the cortico-limbic affective regions was meaningful, with the coefficient λ being positively associated with self-reported emotional reactivity. The FC between the pons and the cortico-limbic-striatal areas was related to self-reported negative affect. Corroborating this finding was the observation that the tract passing through the pons and the left hippocampus was negatively related to self-reported positive affect and positively correlated with emotional reactivity. Our findings support the framework that the pons works conjunctively with the distributed cortico-limbic-striatal systems in shaping individuals' affective states and reactivity. Our work paves the path for future research on the contribution of the pons to the precipitation and maintenance of affective disorders.published_or_final_versio
Validation of the Chinese version of the Oswestry Disability Index
This study aimed to collect evidence on the structural and substantive validity, and test-retest reliability of the Chinese version of the Oswestry Disability Index (CODI). Seventy-nine patients suffering from chronic low back pain were assessed with the CODI. The results of explorative factor analysis primarily suggested a single-factor structure with nine out of 10 items (factor loading = 0.66-0.79). The sex life item was found to load on a different factor. The Cronbach\u27s alpha of all 10 items was 0.81 (p \u3c 0.05). When the sex life item was removed from the analysis, the alpha value was increased to 0.89 (p \u3c 0.05). The test-retest reliability was estimated based on 56 participants who completed two administrations of CODI in 48 hours. The intraclass correlation coefficient (ICC) computed for the total CODI scores was 0.86 (95% C.I. = 0.81-0.91). The reliability estimated for the item scores using Kappa statistics ranged from a high of k = 0.80 for the sitting item to a low of k = 0.49 for the traveling item. Kappa statistics were not available for three items. The Chinese version of the Oswestry Disability Index demonstrated satisfactory validity and test-retest reliability, and so could be considered as an appropriate instrument for assessing chronic back pain-related disability in Chinese patients in Hong Kong. Further research should address the cross-cultural and measurement issues in regard to sex life in order to further improve the test content of the instrument. © 2005 IOS Press. All rights reserved
Role of kinaesthetic motor imagery in mirror-induced visual illusion as intervention in post-stroke rehabilitation
Task complexity and image clarity facilitate motor and visuo-motor activities in mirror therapy in post-stroke patients
Does task complexity influence motor facilitation and visuo-motor memory during mirror therapy in post-stroke patients?
Normative Data for Neuropsychological Measures of Fluency, Attention, and Memory Measures for Hong Kong Chinese
Frontopolar cortex represents complex features and decision value during choice between environments
Summary: Important decisions often involve choosing between complex environments that define future item encounters. Despite its importance for adaptive behavior and distinct computational challenges, decision-making research primarily focuses on item choice, ignoring environment choice altogether. Here we contrast previously studied item choice in ventromedial prefrontal cortex with lateral frontopolar cortex (FPl) linked to environment choice. Furthermore, we propose a mechanism for how FPl decomposes and represents complex environments during decision making. Specifically, we trained a choice-optimized, brain-naive convolutional neural network (CNN) and compared predicted CNN activation with actual FPl activity. We showed that the high-dimensional FPl activity decomposes environment features to represent the complexity of an environment to make such choice possible. Moreover, FPl functionally connects with posterior cingulate cortex for guiding environment choice. Further probing FPl’s computation revealed a parallel processing mechanism in extracting multiple environment features