Solitary hepatic lymphangioma: a one-case report

Hepatic lymphangiomas, malformations of the liver lymphatic system, are extremely rare conditions in adults. A 41-year-old man presented with right upper abdominal pain for 6 months was introduced in this report. Ultrasound (US) and computed tomography (CT) scan demonstrated a giant cystictumor with a pedunculatedextrahepatic growth pattern. Due to diagnostic uncertainty, a partial hepatectomy was performed and pathological results confirmed the diagnosis of solitary hepatic lymphangioma. In this article, we reviewed the clinical and pathology features, preoperative diagnostic challenges, and treatments of hepaticlymphangiomas

Origin of Chemisorption Energy Scaling Relations over Perovskite Surfaces

Rationally tailored perovskites ABO3 are promising substitutes for expensive noble-metal catalysts in heterogeneous catalysis. In this contribution, the BEEF-vdW + U method has been used to examine the adsorption of H, C, O, and CH3 over (K,Rb,Cs,Sr,Ba)BO3 (B = d-block transition metals) and ARuO3 (A = La to Ho) with various crystal structures. The calculated chemisorption energy of the simple species at the O site scales well with the surface oxygen vacancy formation energy of all the perovskites under consideration, while the trend in the chemisorption energy at the B site can be described by the surface metal vacancy formation energy only over ARuO3. Electronic structure analysis indicates that the perovskites could be classified into several categories according to the splitting and filling of the d and f orbitals of the B- and A-site cations, respectively. In each category, the chemisorption energies at the B site on (K,Rb,Cs,Sr,Ba)BO3 and ARuO3 are also closely related to the strength of the ionic bonding in the perovskites. Hence, the surface oxygen vacancy formation energy can be used as a descriptor to explain the trend in the calculated adsorption energies upon substitution of either B- or A-site cations, which has its origin in the fact that the larger the actual partial charges the oxygen and transition-metal ions carry, the stronger the B–O bond, which in turn weakens and enhances the ability of the O anions to withdraw and the ability of the B cations to donate electrons to the adsorbates, respectively.acceptedVersionLocked until 29.10.2020 due to copyright restrictions. This document is the Accepted Manuscript version of a Published Work that appeared in final form in [Journal of Physical Chemistry C], copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.jpcc.9b0874

Results of en bloc resection for hepatocellular carcinoma extending to adjacent organs

BACKGROUND: To curatively resect hepatocellular carcinoma (HCC) with adjacent organ extension, the combined resection of these organs is inevitable. We analyzed the safety and effectiveness of en bloc resection for HCC extending to adjacent organs. METHODS: From December 2002 to May 2006, we compared the surgical outcomes of patients with HCC extending to adjacent organs with those of closely matched, randomly selected patients with HCC without adjacent organ extension. RESULTS: We included 42 patients whose HCC extended to adjacent organs and 126 patients whose HCC did not extend to adjacent organs. There was no significant difference in survival, operative morbidity or mortality between the groups. In patients with HCC extending to adjacent organs, histopathological examination of the specimen revealed true tumour invasion in 13 and adhesion in 29 patients. Those with tumour invasion were more likely to have a high incidence of capsule infiltration, microvascular invasion and early intrahepatic recurrence (≤ 1 yr after hepatectomy). The 5-year overall survival of patients with tumour invasion was 11.5%, whereas that of patients with tumour adhesion was 38.1% (p = 0.033). CONCLUSION: En bloc resection is a safe and effective therapy for HCC extending to adjacent organs. Tumour invasion to adjacent organs exhibits a more aggressive clinical behaviour and is associated with worse survival than tumour adhesion

Deformation and Failure Mechanism of the Lower Roadway in a Close-Range Residual Coal Pillar Area

The Tashan coal mine is selected as a case study to determine the deformation and damage mechanisms of the lower roadway in a close-range residual coal pillar area. Roof drilling peephole technology is applied to detect the damage to the roadway roof surrounding rock. A boundary invisibility equation is derived for the plastic zone of a circular hole based on the theory of a butterfly plastic zone in a non-uniform stress field in which the principal stress occurs at an arbitrary angle to the vertical. Maple mathematical drawing software is combined with FLAC3D numerical simulations to investigate the influence of the principal stress ratio and direction on the roadway plastic zone. The results indicate that the plastic zone of the roadway surrounding rock assumes a butterfly shape when the bidirectional stress ratio is large, and the direction of the butterfly-shaped failure of the roadway is related to the principal stress direction. Field test images are combined to show that the asymmetric damage pattern of the lower roadway in a close-range residual coal pillar area is influenced by the presence of the roadway in a non-uniform stress field in which the main stress direction is deflected

Bamboo charcoal as electrode material for vanadium redox flow batteries

Large-scale energy storage is becoming more critical since the share of energy from renewable sources has increased steadily in recent years. Vanadium redox flow batteries (VRFBs) are a promising candidate for such applications. However, this technique still needs to overcome challenges to enhance battery efficiency, and the investigation of new electrode materials is crucial in this process. In this study, we evaluate bamboo charcoal (BC) as an electrode material for VRFBs for the first time. Bamboo is a rapidly growing renewable carbon source and is thermally treated for use in electrochemical applications. The structure, wettability, wetting behavior, and electrochemical performance of differently-doped BC electrodes are investigated in detail. Scanning electron microscopy and X-ray micro- and nano-computed tomography show the promising channel structure of BC, beneficial for the electrolyte transport through the electrode. Additionally, synchrotron-based time-resolved X-ray radiography and micro tomography was used for an in situ study of the electrolyte flow through the BC channels. These investigations and the dynamic vapor sorption measurements prove that the aqueous electrolyte wets the material easily. Furthermore, we studied the electrochemical performance using cyclic voltammetry and electrochemical impedance spectroscopy combined with the distribution of relaxation times analysis. The undoped BC turned out to have a high catalytic activity towards the vanadium redox reaction, whereas the N-doped BC exhibits improved wettability. In conclusion, BC has great potential to be a suitable and renewable VRFB electrode material

Facile bioactive transformation of magnesium alloy surfaces for surgical implant applications

The market for orthopedic implant alloys has seen significant growth in recent years, and efforts to reduce the carbon footprint of medical treatment (i.e., green medicine) have prompted extensive research on biodegradable magnesium-based alloys. Magnesium alloys provide the mechanical strength and biocompatibility required of medical implants; however, they are highly prone to corrosion. In this study, Mg-9Li alloy was immersed in cell culture medium to simulate degradation in the human body, while monitoring the corresponding effects of the reaction products on cells. Variations in pH revealed the generation of hydroxyl groups, which led to cell death. At day-5 of the reaction, a coating of MgCO3 (H2O)3, HA, and α -TCP appeared on sample surfaces. The coating presented three-dimensional surface structures (at nanometer to submicron scales), anti-corrosion effects, and an altered surface micro-environment conducive to the adhesion of osteoblasts. This analysis based on bio-simulation immersion has important implications for the clinical use of Mg alloys to secure regenerated periodontal tissue

Mimotopes selected with neutralizing antibodies against multiple subtypes of influenza A

<p>Abstract</p> <p>Background</p> <p>The mimotopes of viruses are considered as the good targets for vaccine design. We prepared mimotopes against multiple subtypes of influenza A and evaluate their immune responses in flu virus challenged Balb/c mice.</p> <p>Methods</p> <p>The mimotopes of influenza A including pandemic H1N1, H3N2, H2N2 and H1N1 swine-origin influenza virus were screened by peptide phage display libraries, respectively. These mimotopes were engineered in one protein as multi- epitopes in Escherichia coli (E. coli) and purified. Balb/c mice were immunized using the multi-mimotopes protein and specific antibody responses were analyzed using hemagglutination inhibition (HI) assay and enzyme-linked immunosorbent assay (ELISA). The lung inflammation level was evaluated by hematoxylin and eosin (HE).</p> <p>Results</p> <p>Linear heptopeptide and dodecapeptide mimotopes were obtained for these influenza virus. The recombinant multi-mimotopes protein was a 73 kDa fusion protein. Comparing immunized infected groups with unimmunized infected subsets, significant differences were observed in the body weight loss and survival rate. The antiserum contained higher HI Ab titer against H1N1 virus and the lung inflammation level were significantly decreased in immunized infected groups.</p> <p>Conclusions</p> <p>Phage-displayed mimotopes against multiple subtypes of influenza A were accessible to the mouse immune system and triggered a humoral response to above virus.</p