37 research outputs found
A Novel Reputation Management Mechanism with Forgiveness in P2P File Sharing Networks
AbstractIn peer-to-peer (P2P) file sharing networks, it is common practice to manage each peer using reputation systems. A reputation system systematically tracks the reputation of each peer and punishes peers for malicious behaviors (like uploading bad file, or virus, etc). However, current reputation systems could hurt the normal peers, since they might occasionally make mistakes. Therefore, in this paper, we introduce forgiveness mechanism into the EigenTrust reputation system to reduce such malicious treatments and give them opportunities to gain reputation back. Particularly, we take four motivations (the severity of current offence, the frequency of offences, the compensation and the reciprocity of the offender) into consideration to measure forgiveness. The simulation work shows that the forgiveness model can repair the direct trust breakdown caused by unintentional mistakes and lead to less invalid downloads, which improves the performance of P2P file sharing systems
A-Eval: A Benchmark for Cross-Dataset Evaluation of Abdominal Multi-Organ Segmentation
Although deep learning have revolutionized abdominal multi-organ
segmentation, models often struggle with generalization due to training on
small, specific datasets. With the recent emergence of large-scale datasets,
some important questions arise: \textbf{Can models trained on these datasets
generalize well on different ones? If yes/no, how to further improve their
generalizability?} To address these questions, we introduce A-Eval, a benchmark
for the cross-dataset Evaluation ('Eval') of Abdominal ('A') multi-organ
segmentation. We employ training sets from four large-scale public datasets:
FLARE22, AMOS, WORD, and TotalSegmentator, each providing extensive labels for
abdominal multi-organ segmentation. For evaluation, we incorporate the
validation sets from these datasets along with the training set from the BTCV
dataset, forming a robust benchmark comprising five distinct datasets. We
evaluate the generalizability of various models using the A-Eval benchmark,
with a focus on diverse data usage scenarios: training on individual datasets
independently, utilizing unlabeled data via pseudo-labeling, mixing different
modalities, and joint training across all available datasets. Additionally, we
explore the impact of model sizes on cross-dataset generalizability. Through
these analyses, we underline the importance of effective data usage in
enhancing models' generalization capabilities, offering valuable insights for
assembling large-scale datasets and improving training strategies. The code and
pre-trained models are available at
\href{https://github.com/uni-medical/A-Eval}{https://github.com/uni-medical/A-Eval}
SAM-Med3D
Although the Segment Anything Model (SAM) has demonstrated impressive
performance in 2D natural image segmentation, its application to 3D volumetric
medical images reveals significant shortcomings, namely suboptimal performance
and unstable prediction, necessitating an excessive number of prompt points to
attain the desired outcomes. These issues can hardly be addressed by
fine-tuning SAM on medical data because the original 2D structure of SAM
neglects 3D spatial information. In this paper, we introduce SAM-Med3D, the
most comprehensive study to modify SAM for 3D medical images. Our approach is
characterized by its comprehensiveness in two primary aspects: firstly, by
comprehensively reformulating SAM to a thorough 3D architecture trained on a
comprehensively processed large-scale volumetric medical dataset; and secondly,
by providing a comprehensive evaluation of its performance. Specifically, we
train SAM-Med3D with over 131K 3D masks and 247 categories. Our SAM-Med3D
excels at capturing 3D spatial information, exhibiting competitive performance
with significantly fewer prompt points than the top-performing fine-tuned SAM
in the medical domain. We then evaluate its capabilities across 15 datasets and
analyze it from multiple perspectives, including anatomical structures,
modalities, targets, and generalization abilities. Our approach, compared with
SAM, showcases pronouncedly enhanced efficiency and broad segmentation
capabilities for 3D volumetric medical images. Our code is released at
https://github.com/uni-medical/SAM-Med3D
Genome-wide association for milk production and lactation curve parameters in Holstein dairy cows
The aim of this study was to identify genomic regions associated with 305-day milk yield and lactation curve parameters on primiparous (n = 9,910) and multiparous (n = 11,158) Holstein cows. The SNP solutions were estimated using a weighted single-step genomic BLUP approach and imputed high-density panel (777k) genotypes. The proportion of genetic variance explained by windows of 50 consecutive SNP (with an average of 165 Kb) was calculated, and regions that accounted for more than 0.50% of the variance were used to search for candidate genes. Estimated heritabilities were 0.37, 0.34, 0.17, 0.12, 0.30 and 0.19, respectively, for 305-day milk yield, peak yield, peak time, ramp, scale and decay for primiparous cows. Genetic correlations of 305-day milk yield with peak yield, peak time, ramp, scale and decay in primiparous cows were 0.99, 0.63, 0.20, 0.97 and -0.52, respectively. The results identified three windows on BTA14 associated with 305-day milk yield and the parameters of lactation curve in primi- and multiparous cows. Previously proposed candidate genes for milk yield supported by this work include GRINA, CYHR1, FOXH1, TONSL, PPP1R16A, ARHGAP39, MAF1, OPLAH and MROH1, whereas newly identified candidate genes are MIR2308, ZNF7, ZNF34, SLURP1, MAFA and KIFC2 (BTA14). The protein lipidation biological process term, which plays a key role in controlling protein localization and function, was identified as the most important term enriched by the identified genes
Expert-based development of a generic HACCP-based risk management system to prevent critical negative energy balance in dairy herds
The objective of this study was to develop a generic risk management system based on the Hazard Analysis and Critical Control Point (HACCP) principles for the prevention of critical negative energy balance (NEB) in dairy herds using an expert panel approach. In addition, we discuss the advantages and limitations of the system in terms of implementation in the individual dairy herd. For the expert panel, we invited 30 researchers and advisors with expertise in the field of dairy cow feeding and/or health management from eight European regions. They were invited to a Delphi-based set-up that included three inter-correlated questionnaires in which they were asked to suggest risk factors for critical NEB and to score these based on 'effect' and 'probability'. Finally, the experts were asked to suggest critical control points (CCPs) specified by alarm values, monitoring frequency and corrective actions related to the most relevant risk factors in an operational farm setting. A total of 12 experts (40 %) completed all three questionnaires. Of these 12 experts, seven were researchers and five were advisors and in total they represented seven out of the eight European regions addressed in the questionnaire study. When asking for suggestions on risk factors and CCPs, these were formulated as 'open questions', and the experts' suggestions were numerous and overlapping. The suggestions were merged via a process of linguistic editing in order to eliminate doublets. The editing process revealed that the experts provided a total of 34 CCPs for the 11 risk factors they scored as most important. The consensus among experts was relatively high when scoring the most important risk factors, while there were more diverse suggestions of CCPs with specification of alarm values and corrective actions. We therefore concluded that the expert panel approach only partly succeeded in developing a generic HACCP for critical NEB in dairy cows. We recommend that the output of this paper is used to inform key areas for implementation on the individual dairy farm by local farm teams including farmers and their advisors, who together can conduct herd-specific risk factor profiling, organise the ongoing monitoring of herd-specific CCPs, as well as implement corrective actions when CCP alarm values are exceeded