63 research outputs found
4′-Methyl-3-(4-nitrophenyl)-4-phenyl-4,5,1′,2′,3′,4′-hexahydrospiro[isoxazole-5,2′-naphthalen]-1′-one
The title compound, C25H20N2O4, is a new spiro-isoxazoline derivative. It contains a five-membered isoxazoline ring (A), a tetralone unit (E and D), a 4-nitrophenyl substituent (B), and a phenyl ring (C). The isoxazoline ring (A) has an envelope conformation, while the cyclohexenone ring (D) has an intermediate sofa/half-chair conformation. The aromatic ring of the 4-nitrophenyl substituent (B) is inclined at an angle of 78.97 (10)° to the phenyl ring (C). The rigid pharmacophore site, Osp
2—C—C—Osp
3, is characterized by an O⋯O distance of 3.113 (2) Å and an O—C—C—O torsion angle of 97.8 (2)°. In the crystal structure, molecules are linked by C—H⋯O contacts
2-(4-Chlorophenyl)-6-methoxychroman-4-one
In the title molecule, C16H13Cl O3, the two aromatic rings form a dihedral angle of 65.3 (1)°. In the crystal structure, weak intermolecular C—H⋯O hydrogen bonds link the molecules into centrosymmetric dimers, which are further packed into columns propagating in [100] by weak C—H⋯π interactions
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