Structural panels

Vinyl pyridines including vinyl stilbazole materials and vinyl styrylpyridine oligomer materials are disclosed. These vinylpyridines form copolymers with bismaleimides which copolymers have good fire retardancy and decreased brittleness. The cure temperatures of the copolymers are substantially below the cure temperatures of the bismaleimides alone. Reinforced composites made from the cured copolymers are disclosed as well

Vinyl stilbazoles

Vinyl pyridines including vinyl stilbazole materials and vinyl styrylpyridine oligomer materials are disclosed. These vinylpyridines form copolymers with bismaleimides which copolymers have good fire retardancy and decreased brittleness. The cure temperatures of the copolymers are substantially below the cure temperatures of the bismaleimides alone. Reinforced composites made from the cured copolymers are disclosed as well

Intrinsically Disordered Proteins in a Physics-Based World

Intrinsically disordered proteins (IDPs) are a newly recognized class of functional proteins that rely on a lack of stable structure for function. They are highly prevalent in biology, play fundamental roles, and are extensively involved in human diseases. For signaling and regulation, IDPs often fold into stable structures upon binding to specific targets. The mechanisms of these coupled binding and folding processes are of significant importance because they underlie the organization of regulatory networks that dictate various aspects of cellular decision-making. This review first discusses the challenge in detailed experimental characterization of these heterogeneous and dynamics proteins and the unique and exciting opportunity for physics-based modeling to make crucial contributions, and then summarizes key lessons from recent de novo simulations of the structure and interactions of several regulatory IDPs

Introduction to Flap Movement: Reconstruction of Five Similar Nasal Defects Using Different Flaps

There are several options for closure of a given surgical defect after tumor extirpation is confirmed. Flap reconstruction is one of these options. Objective . The purpose of this article is to introduce the three basic types of flap movement: advancement, rotation, and transposition. Methods . Five similar defects located on the nasal sidewall were repaired, each using a different flap design. Results . The optimal flap design for a given defect on a particular patient is based on the answers to a series of questions: Where is the available tissue reservoir? How can tissue be mobilized from the reservoir to cover the defect? How do the resulting tension vectors affect critical structures? Where are the final incision lines? Conclusion . Many factors must be evaluated before determining a method of reconstruction. Flap reconstruction requires a thorough understanding of anatomy and tissue movement.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/72091/1/j.1524-4725.2005.31822.pd

Predicting Intention to Participate in Socially Responsible Collective Action in Social Networking Website Groups

he present study uses the belief-desire-intention (BDI) model to predict group members’ intentions (“we-intention”) to participate in using a social networking site (SNS) for collective action. Participants reported their beliefs about social influence processes, including their beliefs about subjective norms, group norms, and social identity; they also reported their beliefs about using an SNS for a charitable collective action, which was perceived as corporate social responsibility (CSR). The study applied an integrated research framework in the context of the Facebook group “KolorujeMY,” a group with an interest in supporting social causes in Poland. Our structural equation modeling results indicate that social identity has a positive and direct effect on we-intention to use SNS for collective action and that perceived CSR also had a positive and significant impact on we-intention. Similarly, we found that desire has a positive and significant effect on we-intention to use SNS for collective action. Our results also indicate that desire partially mediates the relationship between social influence beliefs and we-intention. Overall, this study provides insight into the understanding of the impact of social influence processes, the role of desire, and perceived CSR beliefs in terms of predicting we-intentions in a social networking environment

Interrogation of alternative splicing events in duplicated genes during evolution

<p>Abstract</p> <p>Background</p> <p>Gene duplication provides resources for developing novel genes and new functions while retaining the original functions. In addition, alternative splicing could increase the complexity of expression at the transcriptome and proteome level without increasing the number of gene copy in the genome. Duplication and alternative splicing are thought to work together to provide the diverse functions or expression patterns for eukaryotes. Previously, it was believed that duplication and alternative splicing were negatively correlated and probably interchangeable.</p> <p>Results</p> <p>We look into the relationship between occurrence of alternative splicing and duplication at different time after duplication events. We found duplication and alternative splicing were indeed inversely correlated if only recently duplicated genes were considered, but they became positively correlated when we took those ancient duplications into account. Specifically, for slightly or moderately duplicated genes with gene families containing 2 - 7 paralogs, genes were more likely to evolve alternative splicing and had on average a greater number of alternative splicing isoforms after long-term evolution compared to singleton genes. On the other hand, those large gene families (contain at least 8 paralogs) had a lower proportion of alternative splicing, and fewer alternative splicing isoforms on average even when ancient duplicated genes were taken into consideration. We also found these duplicated genes having alternative splicing were under tighter evolutionary constraints compared to those having no alternative splicing, and had an enrichment of genes that participate in molecular transducer activities.</p> <p>Conclusions</p> <p>We studied the association between occurrences of alternative splicing and gene duplication. Our results implicate that there are key differences in functions and evolutionary constraints among singleton genes or duplicated genes with or without alternative splicing incidences. It implies that the gene duplication and alternative splicing may have different functional significance in the evolution of speciation diversity.</p

A New and Elementary CP^n Dyonic Magnon

We show that the dressing transformation method produces a new type of dyonic CP^n magnon in terms of which all the other known solutions are either composites or arise as special limits. In particular, this includes the embedding of Dorey's dyonic magnon via an RP^3 subspace of CP^n. We also show how to generate Dorey's dyonic magnon directly in the S^n sigma model via the dressing method without resorting to the isomorphism with the SU(2) principle chiral model when n=3. The new dyon is shown to be either a charged dyon or topological kink of the related symmetric-space sine-Gordon theories associated to CP^n and in this sense is a direct generalization of the soliton of the complex sine-Gordon theory.Comment: 21 pages, JHEP3, typos correcte

The removal of thermally aged films of triacylglycerides by surfactant solutions

Thermal ageing of triacylglycerides (TAG) at high temperatures produces films which resist removal using aqueous surfactant solutions. We used a mass loss method to investigate the removal of thermally aged TAG films from hard surfaces using aqueous solutions of surfactants of different charge types. It was found that cationic surfactants are most effective at high pH, whereas anionics are most effective at low pH and a non-ionic surfactant is most effective at intermediate pH. We showed that the TAG film removal process occurs in several stages. In the first ‘‘lag phase’’ no TAG removal occurs; the surfactant first partitions into the thermally aged film. In the second stage, the TAG film containing surfactant was removed by solubilisation into micelles in the aqueous solution. The effects of pH and surfactant charge on the TAG removal process correlate with the effects of these variables on the extent of surfactant partitioning to the TAG film and on the maximum extent of TAG solubilisation within the micelles. Additionally, we showed how the TAG removal is enhanced by the addition of amphiphilic additives such as alcohols which act as co-surfactants. The study demonstrates that aqueous surfactant solutions provide a viable and more benign alternative to current methods for the removal of thermally aged TAG films