Energy Recovery Clocked Dynamic Logic

Abstrac

Comparative analysis of aroma components and quality of Geotrichum candidum after space mutation breeding

AimThe aroma-producing strain of Geotrichum candidum GDMCC60675 was taken as the research object, the composition of aroma-producing substances of G. candidum was studied, and the target strains of G. candidum suitable for food additives were screened out by mutagenesis.MethodsMutants were obtained by space breeding. The colony morphology and cell morphology of the mutant strain were identified, the phylogenetic tree of the two strains was constructed, and the whole-genome sequences of the wild strain and the mutant strain were compared. The aroma components and key odor compounds of the two strains were analyzed and compared by HS-SPME-GC-MS and E-nose detection, and the data were processed by using the relative odor activity value (ROAV) analysis method.ResultsA mutant strain of G. candidum was found with different characteristics of aroma production compared with wild-type G. candidum. It was found that its colony morphology and cell morphology were similar. However, it was found that the aroma-producing substances produced by the two strains were different, and the key difference compound was phenyl ethyl alcohol, which also proved that the two strains were different, and the main aroma note was different

QTL Mapping Combined With Bulked Segregant Analysis Identify SNP Markers Linked to Leaf Shape Traits in Pisum sativum Using SLAF Sequencing

Leaf shape is an important trait that influences the utilization rate of light, and affects quality and yield of pea (Pisum sativum). In the present study, a joint method of high-density genetic mapping using specific locus amplified fragment sequencing (SLAF-seq) and bulked segregant analysis (BSA) was applied to rapidly detect loci with leaf shape traits. A total of 7,146 polymorphic SLAFs containing 12,213 SNP markers were employed to construct a high-density genetic map for pea. We conducted quantitative trait locus (QTL) mapping on an F2 population to identify QTLs associated with leaf shape traits. Moreover, SLAF-BSA was conducted on the same F2 population to identify the single nucleotide polymorphism (SNP) markers linked to leaf shape in pea. Two QTLs (qLeaf_or-1, qLeaf_or-2) were mapped on linkage group 7 (LG7) for pea leaf shape. Through alignment of SLAF markers with Cicer arietinum, Medicago truncatula, and Glycine max, the pea LGs were assigned to their corresponding homologous chromosomal groups. The comparative genetic analysis showed that pea is more closely related to M. truncatula. Based on the sequencing results of two pools with different leaf shape, 179 associated markers were obtained after association analysis. The joint analysis of SLAF-seq and BSA showed that the QTLs obtained from mapping on a high-density genetic map are convincing due to the closely associated map region with the BSA results, which provided more potential markers related to leaf shape. Thus, the identified QTLs could be used in marker-assisted selection for pea breeding in the future. Our study revealed that joint analysis of QTL mapping on a high-density genetic map and BSA-seq is a cost-effective and accurate method to reveal genetic architecture of target traits in plant species without a reference genome

Low power and robust memory design: Device, circuit and micro-architecture perspectives

As the CMOS technology continues to scale down to achieve higher performance, considerable power dissipation and reduced reliability in circuit functionality are emerging as major obstacles for circuit designs in the nanometer regime. In current micro-processor design, memory is an essential component. In this research, we have investigated techniques to reduce power consumption and to ensure robustness of memory circuits, in particular SRAM caches, from device, circuit and micro-architecture perspectives. From the device optimization perspective, a circuit-aware device design methodology is proposed for SRAM design. The proposed methodology has achieved significant reduction in SRAM cell leakage and access time, 11% and 7%, respectively, for a conventional 6T-SRAM. Also, we have modeled the impact of asymmetric device underlap on transistor characteristics. The benefits of using asymmetric underlap transistors in SRAM designs are evaluated. In addition, since parametric variations have significant impact on the stability of memory cells, the design and test of memories to ensure correct functionality is of considerable interests. In this work, from a circuit perspective, we have proposed a memory testing technique, which reduces the test application time by 29%. Also, we have explored a modeling technique to study the stability of memory cells under parametric variations. To further explore low power techniques in memory design, novel cache micro-architecture is investigated. In this research, an optimized micro-processor architecture based on dynamic loop detection directed cache (DLDDC ) is proposed. The proposed architecture takes advantages of the frequent executions of loops in program codes. Through dynamic loop detection, accurate way-prediction in set-associative data cache is achieved. The studies show that DLDDC can improve power dissipation in a micro-processor core by 12%, compared to a conventional architecture design. Furthermore, the overheads of DLDDC in terms of area and its own power consumption are negligible

Novel Co/UiO-66 metal organic framework catalyst for oxygen reduction reaction in microbial fuel cells

To improve the power generation of microbial fuel cell (MFC), the cathode is modified to increase its oxygen reduction reaction (ORR) activity by using Co/UiO-66, which derived from pyrolyzing the mixture of Co(NO3)2 as the metal precursor incorporated with NH2-UiO-66. It was found that Co/UiO-66 (MOF-900) has been developed as a high-performance electrocatalyst for ORR at a pyrolysis temperature of 900 °C. Therefore, Co/UiO-66 should be a promising oxygen reduction catalyst for application in MFCs. This study provides technical and theoretical validation for the MFC performance improvement by ORR active MOF-derived catalysts modified cathodes

The discovery and clinical significance of the “Twin Open Skylight and Summon Effects” of the Ilizarov tibial transverse transport technique

Ilizarov’s tibial transverse transport (TTT) technique can promote vascular regeneration. It has been used in the treatment of a variety of lower limb ischemic diseases, such as thromboangiitis obliterans, diabetic foot ulcers, etc. Recently, several novel therapeutic effects have been discovered based on TTT treatment. For instance, in the treatment of thromboangiitis obliterans, an “Open Skylight Effect” was well defined in which the symptom of resting pain disappeared following tibial cortex osteotomy (Long Qu, 2001). During the treatment of bilateral diabetic foot gangrene, patients that received TTT treatment on the one side of the lower limb were observed to have a simultaneous healing of ulcers on both sides, which was termed as the “Summon Effect” (Qikai Hua, 2017). In 2019, we characterized the above discoveries as the “Twin Open Skylight and Summon Effects”. These findings will inspire more potential clinical applications of TTT technique

Analysis of super cut-off transistors for ultralow power digital logic circuits

10.1109/LPE.2006.4271798International Symposium on Low Power Electronics and Design2-

Establishment and Application of a Grey Quality Gain–Loss Function Model

Based on Grey System Theory and the inverted normal quality gain-loss function, the inverted normal grey quality gain-loss function model is put forward. According to the constant compensation and hyperbolic tangent compensation, the grey quality gain-loss function model with nominal-type characteristics, larger-the-better characteristics and smaller-the-better characteristics is built. A multivariate grey quality gain-loss function model with multiple sub quality indexes and the concept of grey quality gain-loss cost are proposed. Case analysis is applied to the quality control of dam concrete construction, which verifies the applicability of the model and provides an important reference for research on the new theory of dam concrete construction quality control