The role of wind stress in driving the along-shelf flow in the Northwest Atlantic Ocean

Author Posting. © American Geophysical Union, 2021. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Journal of Geophysical Research: Oceans 126(4), (2021): e2020JC016757, https://doi.org/10.1029/2020JC016757.The along-shelf circulation in the Northwest Atlantic (NWA) Ocean is characterized by an equatorward flow from Greenland's south coast to Cape Hatters. The mean flow is considered to be primarily forced by freshwater discharges from rivers and glaciers while its variability is driven by both freshwater fluxes and wind stress. In this study, we hypothesize and test that the wind stress is important for the mean along-shelf flow. A two-layer model with realistic topography when forced by wind stress alone simulates a circulation system on the NWA shelves that is broadly consistent with that derived from observations, including an equatorward flow from Greenland coast to the Mid-Atlantic Bight (MAB). The along-shelf sea-level gradient is close to a previous estimate based on observations. The along-shelf flows exhibit strong seasonal variations with along-shelf transports being strong in fall/winter and weak in spring/summer, consistent with available observations. It is found that the NWA shelf circulation is affected by both wind-driven gyres through their western boundary currents and wind-stress forcing on the shelf especially along the coasts of Newfoundland and Labrador. The local wind stress forcing has more direct impacts on flows in shallower waters along the coast while the open-ocean gyres tend to affect the circulations along the outer shelf. Our conclusion is that wind stress is an important forcing of the main along-shelf flows in the NWA. One objective of this study is to motivate further examination of whether wind stress is as important as freshwater forcing for the mean flow.Both Yang and Chen are also supported by NOAA Climate Program Office's Climate Variability and Prediction Program under grant NA20OAR4310398. JY is supported by Woods Hole Oceanographic Institution (WHOI) W. V. A. Clark Chair for Excellence in Oceanography and NSF Ocean Science Division under grant OCE1634886. Chen is supported by WHOI Independent Research and Development award.2021-09-3

Capacity sharing strategy with sustainable revenue-sharing contracts

This paper develops a duopoly model to analyse capacity sharing strategy and the optimal revenue-sharing contract under a two-part tariff and examines the effects of capacity sharing, cost, and sharing charges in three scenarios. The paper uses the two-part tariff method and adds a more realistic assumption of incremental marginal costs to improve the research on capacity sharing strategies. The results show that capacity constraints affect the sustainable development of firms. A sustainable revenue-sharing contract can create a win-win situation for both firms and promote capacity sharing. Capacity sharing, cost, and the revenue-sharing rate have different impacts in different scenarios; the optimal revenue-sharing rate and fixed fee can be determined to maximise the profits of firms that share capacity. However, capacity sharing may not improve social welfare. First published online 28 December 202

Mesoscale and submesoscale shelf-ocean exchanges initialize an advective marine heatwave

Author Posting. © American Geophysical Union, 2022. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Journal of Geophysical Research: Oceans 127(1), (2022): e2021JC017927, https://doi.org/10.1029/2021JC017927.Observations and high-resolution numerical modeling are used to investigate the dynamical processes related to the initiation of an advective Marine Heatwave in the Middle Atlantic Bight of the Northwest Atlantic continental shelf. Both the observations and the model identify two significant cross-shelf intrusions in November 2016 and January 2017, with the latter inducing large-magnitude water mass anomalies across the shelf. Model prognostic fields reveal the importance of the combination of cyclonic eddies or ringlets and upwelling-favorable winds in producing the large-distance cross-shelf penetration and temperature/salinity anomalies. The cyclonic eddies in close proximity to the shelfbreak set up local along-isobath pressure gradients and provide favorable conditions for the intensification of the shelfbreak front, both processes driving cross-isobath intrusions of warm, salty offshore water onto the outer continental shelf. Subsequently, strong and persistent upwelling-favorable winds drive a rapid, bottom intensified cross-shelf penetration in January 2017 composed of the anomalous water mass off the shelfbreak. The along-shelf settings including realistic representation of bathymetric features are essential in the characteristics of the cross-shelf penetration. The results highlight the importance of smaller scale cyclonic eddies and the intricacy of the interplay between multiple processes to drive significant cross-shelf events.This work was supported by Woods Hole Oceanographic Institution (WHOI) Independent Research and Development (IR&D) award and National Oceanic and Atmospheric Administration (NOAA) Climate Program Office (CPO) Climate Variability and Predictability (CVP) program under grant NA20OAR4310398. Numerical modeling work was conducted at WHOI High-Performance Computing cluster Poseidon with startup support to Ke Chen.2022-06-0

Multi-criteria group decision-making method for green supplier selection based on distributed interval variables

Addressing the multi-criteria group decision making problem with interval attribute values and attribute weights, this paper proposes a decision method based on attribute distribution information. The selection of green suppliers is taken as an example for decision analysis. First, in the case of group decision-making, the quantitative values of the evaluation attributes of green suppliers are imputed by decision-makers, and the relevant distributions are constructed for each attribute. Next, combined with the ranges of attribute values, the random interval values are used to describe the information represented by each attribute to overcome the loss caused by the aggregation of individual expert information into group information. We then propose the distributed interval weighted arithmetic average (DIWAA) operator and corresponding operation rules, which realizes the fusion of qualitative data and quantitative judgment. Thus, the proposed approach allows ensuring reasonable results of the multi-criteria analysis. We also construct a ranking method for alternatives based on distributed interval comprehensive scores. Finally, we verify the feasibility and effectiveness of the proposed method for the task of green supplier selection through numerical experiments

Genomic Features and Clinical Characteristics of Adolescents and Young Adults With Cholangiocarcinoma

Background: Adolescents and young adults (AYAs) diagnosed with cancer between ages 15 and 45 years may exhibit unique biologic and genomic characteristics as well as clinical features, resulting in differences in clinical characters and drug resistance. However, compared to other solid cancers, relatively few studies have been conducted in this age group in cholangiocarcinoma (CCA). This study is performed to investigate the clinical and molecular features of AYAs with CCA. Methods: Three cohorts, including the external dataset (TCGA and MSKCC) and the perihilar CCA databank of Chinese tertiary hospitals, were contained in this study. Pathway and process enrichment analysis had been carried out with the following ontology sources: KEGG Pathway, GO Biological Processes, Reactome Gene Sets, Canonical Pathways, and CORUM. Metascape and GEPIA datasets were used for bioinformatic analysis. P < 0.05 was considered statistically significant. All statistical analyses were performed with GraphPad Prism (version 7.0; GraphPad Software, La Jolla, California) and R studio (version 3.6.1; R studio, Boston, Massachusetts). Results: Compared to older adults, AYAs with CCA presented with worse overall survival, although the difference was not significant. Specific to patients with stage IV CCAs who underwent chemotherapy, AYAs were associated with significantly poorer overall survival (OS) (p = 0.03, hazards ratio (HR) 3.01, 95% confidence interval (CI) 1.14-4.91). From the anatomical perspective, more extrahepatic CCA was detected in the AYA group. Microsatellite instability (MSI) occurred in 3% of older patients in the present study. Nevertheless, none of the AYAs had MSI status. In this study, AYAs gained an enhanced frequency of additional sex combs like 1 (ASXL1) (p = 0.02) and KMT2C (p = 0.02) mutation than their older counterparts. Besides ASXL1 and KMT2C, the genes enriched in AYAs with CCA were analyzed by pathway and process enrichment analysis. And those genes were found to be associated with poorer differentiation, deubiquitination, and WNT signal pathway. Moreover, AYAs were relevant to poor differentiation and advanced tumor stage. Conclusion: This study offered a preliminary landscape of the clinical and molecular features of early-onset biliary cancers. Further studies including more samples are essential to investigate whether ASXL1 and KMT2C could be considered as potentially targetable genomic signatures for young patients