15 research outputs found

    How Cultural Factors Affect Chinese Americans’ Attitudes Towards Seeking Mental Health Services

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    Chinese Americans are the largest ethnic group among Asian Americans. However, the treatment rate for mental illness among Chinese Americans is much lower compared to other ethnic groups. Studies have been conducted on cultural barriers that prevent Asian Americans from seeking mental health treatment, but there is a lack of research on specific ethnic groups, such as Chinese Americans or Korean Americans because they are frequently grouped into homogenous clusters. This study will identify the cultural factors that influence Chinese Americans’ attitudes towards seeking mental health treatment and analyze how these factors affect their behaviors in seeking mental health treatment

    Production of Molybdenum Trioxide Nanosheets by Liquid Exfoliation and Their Application in High-Performance Supercapacitors

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    Speech Communication

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    Contains table of contents for Part V, table of contents for Section 1, an introduction, reports on six research projects and a list of publications.C.J. Lebel FellowshipDennis Klatt Memorial FundDigital Equipment CorporationNational Institutes of Health Grant R01-DC00075National Institutes of Health Grant R03-DC01721National Institutes of Health Grant R01-DC01291National Institutes of Health Grant R01-DC00266National Institutes of Health Grant P01-DC00361-06A1National Institutes of Health Contract R01-DC00776National Science Foundation Grant IRI 89-05249National Science Foundation Grant IRI 89-10561National Science Foundation Grant INT 90-2471

    Secreted heat shock protein gp96-Ig: next-generation vaccines for cancer and infectious diseases

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    Over the past decade, our laboratory has developed a secreted heat shock protein (HSP), chaperone gp96, cell-based vaccine that generates effective anti-tumor and anti-infectious immunity in vivo. Gp96-peptide complexes were identified as an extremely efficient stimulator of MHC I-mediated antigen cross-presentation, generating CD8 cytotoxic T-lymphocyte responses detectable in blood, spleen, gut and reproductive tract to femto-molar concentrations of antigen. These studies provided the first evidence that cell-based gp96-Ig-secreting vaccines may serve as a potent modality to induce both systemic and mucosal immunity. This approach takes advantage of the combined adjuvant and antigen delivery capacity of gp96 for the generation of cytotoxic immunity against a wide range of antigens in both anti-vial and anti-cancer vaccination. Here, we review the vaccine design that utilizes the unique property/ability of endoplasmic HSP gp96 to bind antigenic peptides and deliver them to antigen-presenting cells

    From Gene to Behavior: L-Type Calcium Channel Mechanisms Underlying Neuropsychiatric Symptoms

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    Overall survival in the OlympiA phase III trial of adjuvant olaparib in patients with germline pathogenic variants in BRCA1/2 and high-risk, early breast cancer

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    31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

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