Free Vibration Analysis of a Rectangular Duct with Different Axial Boundary Conditions

3This paper describes the free vibration analysis of a rectangular duct by using the Rayleigh-Ritz method. Static beam functions are used as admissible functions in the Rayleigh-Ritz method. These basis functions are the static solutions of a point-supported beam under a series of sinusoidal loads. The unique advantage of using this method is that it allows for the consideration of different axial boundary conditions of a duct. Computational results are validated with existing literature data for a simply supported rectangular duct and the finite element method (FEM) for other axial boundary conditions. A validated analytical model is used for generating natural frequency data for different dimensions of rectangular ducts. Further curve fitting has been done for the generated data, and an empirical relation has been presented to calculate the first fundamental natural frequency for different material properties of ducts and different axial boundary conditions, which can be used for any dimensions of the duct within the specified range

UTERINE ARTERIOVENOUS MALFORMATION TRANSVAGINAL DOPPLER ULTRASONOGRAPHY: CASE REPORT

Uterine arteriovenous malformation (AVM) is a rare condition, with fewer than 100 cases reported in the literature. Despite it being rare, it is a potentially life-threatening condition. This case report describes a healthy 29-year-old patient, nulligravida, with an unremarkable medical history, came from gynaecologist for ultrasaound due to complain of irregular heavy PV bleeding. Transvaginal Doppler ultrasonography is a widely available, noninvasive and excellent diagnostic method. Transvaginal ultrasound (TVS) of the pelvis showed increased vascularity with multidirectional flow of the uterus and a prominent vessel, located on the posterior wall.KEYWORDS: Arteriovenous malformation; Primary infertility; Transvaginal ultrasound

UTERINE ARTERIOVENOUS MALFORMATION TRANSVAGINAL DOPPLER ULTRASONOGRAPHY: CASE REPORT

Uterine arteriovenous malformation (AVM) is a rare condition, with fewer than 100 cases reported in the literature. Despite it being rare, it is a potentially life-threatening condition. This case report describes a healthy 29-year-old patient, nulligravida, with an unremarkable medical history, came from gynaecologist for ultrasaound due to complain of irregular heavy PV bleeding. Transvaginal Doppler ultrasonography is a widely available, noninvasive and excellent diagnostic method. Transvaginal ultrasound (TVS) of the pelvis showed increased vascularity with multidirectional flow of the uterus and a prominent vessel, located on the posterior wall.KEYWORDS: Arteriovenous malformation; Primary infertility; Transvaginal ultrasound

High Density Planting in Mango cv. Alphonso

A trial was conducted to optimize spacing for high density planting in mango cv. Alphonso to obtain higher yield/ unit area at the Agriculture Research Station, Mulde, during 2006-07 to 2008-09 with four close spacings and one normal spacing as control. Highest yield (6.4 MT/ha) was recorded with a spacing of 5 m x 5 m without reduction in fruit size in 10 year old plants compared to the mean yield of 1.12 MT/ha in 10m x 10m normal spacing. High density plantation helped to get significantly higher yield per unit area compared to the normal spacing, without affecting size and quality of mango fruits. The highest cost:benefit ratio (2.33) was recorded in high density plantation of 5m x 5m, with maximum net returns of Rs.1,12,000/- per hectare. The present findings show promise for more yield and returns per unit area during the initial years of mango plantation by adopting 5m x 5m high density planting

Synthesis and Pharmacological Evaluation of Pyrazoline and Pyrimidine Analogs of Combretastatin-A4 as Anticancer, Anti-inflammatory and Antioxidant Agents

A library of 3,5-diaryl-1-carbothioamide-pyrazoline (5a–j), N1-phenyl sulfonyl pyrazoline (6a–e) and pyrimidine (7a) analogs of combretastatin-A4 were synthesized and evaluated for their in vitro anticancer, anti-inflammatory and antioxidant activity. Results of in vitro assay against human breast cancer cell line (MCF-7) showed several compounds endowed with significant cytotoxicity compared to the adriamycin, a standard anticancer drug. Among the compounds synthesized, 7a was found to possess significant antiproliferative activity (GI50 < 0.1 µM) against the MCF-7 cell line as good as adriamycin (GI50 < 0.1 µM) whereas, compounds 6c, 5j and 5g also displayed good cytotoxicity (GI50 = 25.3–42.6 µM). Besides this, most active compound 7a was also evaluated against human myeloid leukemia cell line K562 and the remarkable result was obtained with GI50 < 0.1 µM, comparable to that of adriamycin (GI50 < 0.1 µM). In addition, all the synthesized compounds were evaluated for their anti-inflammatory and antioxidant activity. The percent inhibition studies revealed that most of the compounds were found to possess substantial anti-inflammatory and antioxidant activities. This work is licensed under a Creative Commons Attribution 4.0 International License

First results of evaporation residue cross-section measurements of 32^{32}S+208^{208}Pb system

The dynamics of heavy ion-induced reactions play a critical role in forming super heavy elements (SHE), and one clear signature of the SHE formation is the evaporation residue (ER). In our pursuit of SHE, we present the heaviest element populated in India for ER cross-section measurements. These are the first-ever measurements of the Evaporation Residue (ER) cross-sections for the nuclear reactions between $^{32}$S and $^{208}$Pb. These measurements were conducted above the Coulomb barrier at four distinct beam energies in the laboratory frame, ranging from 176 to 191 MeV at the pelletron Linac facility at the Inter-University Accelerator Centre (IUAC), New Delhi. The Hybrid Recoil Mass Analyzer (HYRA) in a gas-filled mode was employed for these experiments. The obtained range of ER cross-sections enriches our knowledge and helps advance the field of heavy ion-induced reactions, especially in the context of super heavy element formation.Comment: 12 pages, 10 figures. arXiv admin note: text overlap with arXiv:2311.0904

Design, Synthesis, and Spectroscopic Study of 7-Azaindolyl Hydrazones with Anti-Breast Cancer Activity

A series of 7-azaindolyl hydrazones were prepared by reacting of hydrazides of 7-azaindole-3-acetic acids with aromatic aldehydes and N-substituted indolyl-3-carboxyaldehydes. Structure of all the synthesized compounds were satisfactorily correlated by IR, 1H NMR, 13C NMR and mass spectroscopic evidences. The synthesized compounds were evaluated for their possible anticancer potential against MCF-7 induced breast carcinoma. It is worth mentioning that most of the compounds were considerably active against MCF-7 cell line with GI50 values ranging from 22.3–81.0 μM. The hydrazones of N-1-substituted indole-3-carboxyaldehydes 9f, 9g, 9h, 9c, and 9j were active against MCF-7 cell line with GI50 values less than 40 μM (GI50 = 22.3 and 24.9, 29.6, 30.2 and 37.8 μM respectively) with moderate TGI values (TGI = 56.6, 59.5, 65.5, 70.7 and 94.6 μM respectively). The active compounds were also screened against the normal Vero monkey cell line, which showed moderate selectivity against inhibition of cancer cells. This work is licensed under a Creative Commons Attribution 4.0 International License

Measurements of evaporation residue cross-sections and evaporation residue-gated γ\gamma-ray fold distributions for 32^{32}S+154^{154}Sm system

Evaporation Residue (ER) cross-sections and ER-gated $\gamma$-ray fold distributions are measured for the $^{32}$S + $^{154}$Sm nuclear reaction above the Coulomb barrier at six different beam energies from 148 to 191 MeV. $\gamma$-ray multiplicities and spin distributions are extracted from the ER-gated fold distributions. The ER cross-sections measured in the present work are found to be much higher than what was reported in a previous work using a very different target-projectile ($^{48}$Ti + $^{138}$Ba) combination, leading to the same compound nucleus $^{186}$Pt, with much less mass asymmetry in the entrance channel than the present reaction. This clearly demonstrates the effect of the entrance channel on ER production cross-section. The ER cross-sections measured in the present work are compared with the results of both the statistical model calculations and the dynamical model calculations. Statistical model calculations have been performed to generate a range of parameter space for both the barrier height and Kramers' viscosity parameter over which the ER cross-section data can be reproduced. The calculations performed using the dinuclear system (DNS) model reproduce the data considering both complete and incomplete fusion processes. DNS calculations indicate the need for the inclusion of incomplete fusion channel at higher energies to reproduce the ER cross-sections.Comment: 13 pages, 18 figure