916 research outputs found
Pareto Law in a Kinetic Model of Market with Random Saving Propensity
We have numerically simulated the ideal-gas models of trading markets, where
each agent is identified with a gas molecule and each trading as an elastic or
money-conserving two-body collision. Unlike in the ideal gas, we introduce
(quenched) saving propensity of the agents, distributed widely between the
agents (). The system remarkably self-organizes to a
critical Pareto distribution of money with . We analyse the robustness (universality) of the distribution in the
model. We also argue that although the fractional saving ingredient is a bit
unnatural one in the context of gas models, our model is the simplest so far,
showing self-organized criticality, and combines two century-old distributions:
Gibbs (1901) and Pareto (1897) distributions.Comment: 5 pages RevTeX4, 6 eps figures, to be published in Physica A (2004
Electromagnetic probes
We introduce the seminal developments in the theory and experiments of
electromagnetic probes for the study of the dynamics of relativistic heavy ion
collisions and quark gluon plasma.Comment: 47 pages, 33 Figures; Lectures delivered by Dinesh K. Srivastava at
QGP Winter School (QGPWS08) at Jaipur, India, February 1-3, 200
Higher dimensional dust collapse with a cosmological constant
The general solution of the Einstein equation for higher dimensional (HD)
spherically symmetric collapse of inhomogeneous dust in presence of a
cosmological term, i.e., exact interior solutions of the Einstein field
equations is presented for the HD Tolman-Bondi metrics imbedded in a de Sitter
background. The solution is then matched to exterior HD Scwarschild-de Sitter.
A brief discussion on the causal structure singularities and horizons is
provided. It turns out that the collapse proceed in the same way as in the
Minkowski background, i.e., the strong curvature naked singularities form and
that the higher dimensions seem to favor black holes rather than naked
singularities.Comment: 7 Pages, no figure
Development of Tyrphostin analogues to study inhibition of the Mycobacterium tuberculosis Pup proteasome system**
Tuberculosis is a global health problem caused by infection with the Mycobacterium tuberculosis (Mtb) bacteria. Although antibiotic treatment has dramatically reduced the impact of tuberculosis on the population, the existence and spreading of drug resistant strains urgently demands the development of new drugs that target Mtb in a different manner than currently used antibiotics. The prokaryotic ubiquitin-like protein (Pup) proteasome system is an attractive target for new drug development as it is unique to Mtb and related bacterial genera. Using a Pup-based fluorogenic substrate, we screened for inhibitors of Dop, the Mtb depupylating protease, and identified I-OMe-Tyrphostin AG538 (1) and Tyrphostin AG538 (2). The hits were validated and determined to be fast-reversible, non-ATP competitive inhibitors. We synthesized >25 analogs of 1 and 2 and show that several of the synthesized compounds also inhibit the depupylation actions of Dop on native substrate, FabD-Pup. Importantly, the pupylation activity of PafA, the sole Pup ligase in Mtb, was also inhibited by some of these compounds.Chemical Immunolog
Citizenship status and career self-efficacy: An intersectional study of biomedical trainees in the United States
This study examines the intersectional role of citizenship and gender with career self-efficacy amongst 10,803 doctoral and postdoctoral trainees in US universities. These biomedical trainees completed surveys administered by 17 US institutions that participated in the National Institutes of Health Broadening Experiences in Scientific Training (NIH BEST) Programs. Findings indicate that career self-efficacy of non-citizen trainees is significantly lower than that of US citizen trainees. While lower career efficacy was observed in women compared with men, it was even lower for non-citizen female trainees. Results suggest that specific career interests may be related to career self-efficacy. Relative to US citizen trainees, both male and female non-citizen trainees showed higher interest in pursuing a career as an academic research investigator. In comparison with non-citizen female trainees and citizen trainees of all genders, non-citizen male trainees expressed the highest interest in research-intensive (and especially principal investigator) careers. The authors discuss potential causes for these results and offer recommendations for increasing trainee career self-efficacy which can be incorporated into graduate and postdoctoral training
Inverse magnetic catalysis in field theory and gauge-gravity duality
We investigate the surface of the chiral phase transition in the
three-dimensional parameter space of temperature, baryon chemical potential and
magnetic field in two different approaches, the field-theoretical
Nambu-Jona-Lasinio (NJL) model and the holographic Sakai-Sugimoto model. The
latter is a top-down approach to a gravity dual of QCD with an asymptotically
large number of colors and becomes, in a certain limit, dual to an NJL-like
model. Our main observation is that, at nonzero chemical potential, a magnetic
field can restore chiral symmetry, in apparent contrast to the phenomenon of
magnetic catalysis. This "inverse magnetic catalysis" occurs in the
Sakai-Sugimoto model and, for sufficiently large coupling, in the NJL model and
is related to the physics of the lowest Landau level. While in most parts our
discussion is a pedagogical review of previously published results, we include
new analytical results for the NJL approach and a thorough comparison of
inverse magnetic catalysis in the two approaches.Comment: 37 pages, 11 figures, to appear in Lect. Notes Phys. "Strongly
interacting matter in magnetic fields" (Springer), edited by D. Kharzeev, K.
Landsteiner, A. Schmitt, H.-U. Ye
Career self-efficacy disparities in underrepresented biomedical scientist trainees
The present study examines racial, ethnic, and gender disparities in career self-efficacy amongst 6077 US citizens and US naturalized graduate and postdoctoral trainees. Respondents from biomedical fields completed surveys administered by the National Institutes of Health Broadening Experiences in Scientific Training (NIH BEST) programs across 17 US institutional sites. Graduate and postdoctoral demographic and survey response data were examined to evaluate the impact of intersectional identities on trainee career self-efficacy. The study hypothesized that race, ethnicity and gender, and the relations between these identities, would impact trainee career self-efficacy. The analysis demonstrated that racial and ethnic group, gender, specific career interests (academic principal investigator vs. other careers), and seniority (junior vs. senior trainee level) were, to various degrees, all associated with trainee career self-efficacy and the effects were consistent across graduate and postdoctoral respondents. Implications for differing levels of self-efficacy are discussed, including factors and events during training that may contribute to (or undermine) career self-efficacy. The importance of mentorship for building research and career self-efficacy of trainees is discussed, especially with respect to those identifying as women and belonging to racial/ethnic populations underrepresented in biomedical sciences. The results underscore the need for change in the biomedical academic research community in order to retain a diverse biomedical workforce
Magnetic fields in supernova remnants and pulsar-wind nebulae
We review the observations of supernova remnants (SNRs) and pulsar-wind
nebulae (PWNe) that give information on the strength and orientation of
magnetic fields. Radio polarimetry gives the degree of order of magnetic
fields, and the orientation of the ordered component. Many young shell
supernova remnants show evidence for synchrotron X-ray emission. The spatial
analysis of this emission suggests that magnetic fields are amplified by one to
two orders of magnitude in strong shocks. Detection of several remnants in TeV
gamma rays implies a lower limit on the magnetic-field strength (or a
measurement, if the emission process is inverse-Compton upscattering of cosmic
microwave background photons). Upper limits to GeV emission similarly provide
lower limits on magnetic-field strengths. In the historical shell remnants,
lower limits on B range from 25 to 1000 microGauss. Two remnants show
variability of synchrotron X-ray emission with a timescale of years. If this
timescale is the electron-acceleration or radiative loss timescale, magnetic
fields of order 1 mG are also implied. In pulsar-wind nebulae, equipartition
arguments and dynamical modeling can be used to infer magnetic-field strengths
anywhere from about 5 microGauss to 1 mG. Polarized fractions are considerably
higher than in SNRs, ranging to 50 or 60% in some cases; magnetic-field
geometries often suggest a toroidal structure around the pulsar, but this is
not universal. Viewing-angle effects undoubtedly play a role. MHD models of
radio emission in shell SNRs show that different orientations of upstream
magnetic field, and different assumptions about electron acceleration, predict
different radio morphology. In the remnant of SN 1006, such comparisons imply a
magnetic-field orientation connecting the bright limbs, with a non-negligible
gradient of its strength across the remnant.Comment: 20 pages, 24 figures; to be published in SpSciRev. Minor wording
change in Abstrac
Lattice QCD Simulations in External Background Fields
We discuss recent results and future prospects regarding the investigation,
by lattice simulations, of the non-perturbative properties of QCD and of its
phase diagram in presence of magnetic or chromomagnetic background fields.
After a brief introduction to the formulation of lattice QCD in presence of
external fields, we focus on studies regarding the effects of external fields
on chiral symmetry breaking, on its restoration at finite temperature and on
deconfinement. We conclude with a few comments regarding the effects of
electromagnetic background fields on gluodynamics.Comment: 31 pages, 10 figures, minor changes and references added. To appear
in Lect. Notes Phys. "Strongly interacting matter in magnetic fields"
(Springer), edited by D. Kharzeev, K. Landsteiner, A. Schmitt, H.-U. Ye
Pulsar-wind nebulae and magnetar outflows: observations at radio, X-ray, and gamma-ray wavelengths
We review observations of several classes of neutron-star-powered outflows:
pulsar-wind nebulae (PWNe) inside shell supernova remnants (SNRs), PWNe
interacting directly with interstellar medium (ISM), and magnetar-powered
outflows. We describe radio, X-ray, and gamma-ray observations of PWNe,
focusing first on integrated spectral-energy distributions (SEDs) and global
spectral properties. High-resolution X-ray imaging of PWNe shows a bewildering
array of morphologies, with jets, trails, and other structures. Several of the
23 so far identified magnetars show evidence for continuous or sporadic
emission of material, sometimes associated with giant flares, and a few
possible "magnetar-wind nebulae" have been recently identified.Comment: 61 pages, 44 figures (reduced in quality for size reasons). Published
in Space Science Reviews, "Jets and Winds in Pulsar Wind Nebulae, Gamma-ray
Bursts and Blazars: Physics of Extreme Energy Release
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