Hematological profile including alkali resistant hemoglobin of neonates at birth using cord blood in relation to gestational age and maternal diseases

Background: The importance of complete hemogram along with the hematological indices in the diagnosis of neonatal health cannot be overemphasized. There is a severe paucity of relevant data regarding neonatal hematological profile in relation to gestational age and maternal diseases in this part of the country. With this perspective, the authors intended to do a pilot study to analyse the haematological profile of neonates of different gestational ages and different maternal diseases born in a teriary care hospital in Eastern India.Methods: This is a cross sectional study design based on cord blood sample of newborns and their mothers recruited from those admitted in the gynae and obstetric department in IPGME&R. The umbilical cord blood was collected from the newborn babies and then examined for different haematological parameters. The data obtained was statistically analysed.Results: While there has been a sequential rise of fetal red cell count, hemoglobin and the total white cell count neutrophils with gestational age, the mean corpuscular cell volume decreased. All these values were comprised to varying degrees in maternal diseases except for nucleated rell blood cells which conspicuously increased in neonates of diabetic mothers.Conclusions: In this study, a small attempt was made to assess the haematological profile (including alkali resistant hemoglobin) of the newborns in relation to gestational age and maternal diseases in the population attending a tertiary care hospital in Eastern India

isolated soft switched boost dc dc converter with low voltage stress and high step up ratio

This study presents a novel soft-switched isolated boost converter which can provide a high-step-up ratio and high efficiency with low-voltage stress for portable application as well as a photovoltaic-assisted converter system. A lossless active clamp snubber circuit helps in achieving zero-voltage-switching turn-off and zero-current-switching (ZCS) turn-on of the main switch and ZCS turn-off of diodes that reduce switching losses. An auxiliary switch with an energy recovery circuit helps to increase power conversion efficiency and reduces switching stress across the main switch. The proposed idea is simulation through computer-assisted software PSIM 9.1.1 and validated experimentally through a designed prototype 250 W direct current (DC)–DC converter