7,662 research outputs found
Giant D5 Brane Holographic Hall State
We find a new holographic description of strongly coupled defect field
theories using probe D5 branes. We consider a system where a large number of
probe branes, which are asymptotically D5 branes, blow up into a D7 brane
suspended in the bulk of anti-de Sitter space. For a particular ratio of charge
density to external magnetic field, so that the Landau level filling fraction
per color is equal to one, the D7 brane exhibits an incompressible
charge-gapped state with one unit of integer quantized Hall conductivity. The
detailed configuration as well as ungapped, compressible configurations for a
range of parameters near the gapped one are found by solving the D5 and D7
brane embedding equations numerically and the D7 is shown to be preferred over
the D5 by comparing their energies. We then find integer quantum Hall states
with higher filling fractions as a stack of D5 branes which blow up to multiple
D7 branes where each D7 brane has filling fraction one. We find indications
that the n D7 branes describing the filling fraction n state are coincident
with a residual SU(n) symmetry when n is a divisor of the total number of D5
branes. We examine the issue of stability of the larger filling fraction Hall
states. We argue that, in the D7 brane phase, chiral symmetry restoration could
be a first order phase transition.Comment: 30 pages, 15 figures, typos fixed, some clarifying comments adde
Chromatographic separation and identification of some peptides in partial hydroylsates of gelatin
Recently we have been engaged in a study of the chemical structure of collagen and gelatin with the object of determining the sequence of the amino acid residues in the polypeptide chains of these proteins. In the course of this study we have made considerable progress in the chromatographic analysis of complex mixtures of peptides and we have isolated and identified several simple peptides which occur in partial hydrolysates of gelatin. The initial separation of the mixture into zones of one or more peptides has been made on a column of ion exchange resin; further separation of the peptides in each zone has been achieved by chromatographing in the form of dinitrophenyl (DNP) peptides on columns of silicic acid-Celite. It is to be hoped that the particular combination of chromatographic methods which has been successfully used in the present study will be helpful in the resolution of the complex mixtures which result from the partial hydrolysis of other proteins
Sex Hormones and Sympathetic Nerve Activity
The purpose of this thesis was to test the hypothesis that changes in circulating sex hormone levels are associated with changes in muscle sympathetic nerve activity. The hypothesis was tested through the comparison of low- (early follicular [EF]) and high-hormone (midluteal [ML]) phases of the menstrual cycle and of hormonal contraceptive use (low hormone [LH] versus high hormone [HH]). The microneurography technique was used to compare both the frequency and size of bursts in muscle sympathetic nerve activity (MSNA) at baseline and during two sympatho-excitatory maneuvers: baroreceptor unloading elicited through lower body negative pressure, and chemoreflex stimulation elicited through a hypoxic-hypercapnic end-inspiratory apnea. Sympathetic responses to chemoreflex stimulation were also compared between women and men. All associations between MSNA and hormone phases occurred similarly between users and non-users of hormonal contraceptives. At baseline, MSNA was relatively elevated during the high hormone phases (ML and HH), at which point baseline sympathetic activity was similar to that observed in men. However, stimulation of the chemoreflex resulted in greater sympathetic activation during the low hormone phases (EF and LH) relative to the high hormone phases. Further, this hormone phase effect was mediated largely by greater increases in burst size, rather than the burst frequency component. This may indicate that central integration sites for MSNA are affected by circulating sex hormone levels. Finally, the sympathetic responses to baroreceptor unloading were graded to reductions in stroke volume, which, in turn, were affected by hormone levels. However, no evidence was observed to suggest a change in the central integration of baroreceptor afferent input occurred across phases of the menstrual cycle or hormonal contraceptive use in terms of baroreflex function. Together, these studies confirm that sympathetic nerve activity at baseline and sympathetic recruitment during chemoreflex stimulation are affected by hormone phase, while baroreceptor-mediated responses are not affected by the transition from low (EF and LH) to high hormone phases (ML and HH)
Reported worker characteristics for entry-level employees in information processing.
The population consisted of the major employers (those with five hundred or more employees) in the Oklahoma City Metropolitan Area as listed in the "Statistical Abstract of Oklahoma 1980." The study was limited to the companies which were computer-based within the State of Oklahoma. Thirty-two companies participated in the project.Analyzed and evaluated in this study were worker characteristics and skills deemed necessary by managers in business and industry to secure employment and to succeed in the area of Information Processing.Statistics were compiled on one hundred and sixty items taken from the interview-questionnaire. A Condescriptive Program computed the statistical mean on a five-point scale as to the importance of each item and percentile responses were illustrated through the use of a Crosstabs Program. For additional background information concerning the population, five items relating to demographic factors of the companies were tabulated.An interview-questionnaire was developed and was submitted to a panel of experts for validation. The experts were members of the Business Advisory Committee for the Business and Economics Department at the University of Science and Arts of Oklahoma. For validation by business and industry, five companies were selected from the population and personal interviews were conducted with those companies
Career Expectations of High School Seniors in Two Selected High Schools
An applied project submitted in partial fulfillment of the requirements for the degree of Education Specialist at Morehead State University by Charlotte W. Gillum on May 4, 1977
Asset-Based Community Capacity Building: A Process for Expanding a Retirement Home Physical Activity Program
The population is aging rapidly and physical inactivity and sedentary behaviour are on the rise, a trend noticed at a northern Ontario retirement home looking to improve the choices for, and attendance at, physical activities provided for residents. A community capacity building (CCB) approach using an asset-based, partnership methodology was utilized to create internal and external asset maps. These maps were used to inform potential partnerships within the community. Partnerships were recommended with a university, college, and two high schools, whose staff and students could help to implement new physical activities. Walking and gardening clubs were presented as examples that could be implemented using identified assets. An adapted model was then presented that the home could use in the future to explore other partnerships and continue to build capacity for its physical activity program
Body mass index and age affect Three-Factor Eating Questionnaire scores in male subjects
This cross-sectional analysis evaluated the effect of age and body mass index (BMI) on Three-Factor Eating Questionnaire scores in males. Subjects (n = 60) were recruited according to BMI status. Each completed the 51-item Three-Factor Eating Questionnaire. The group was split at the median age to produce a "younger" and "older" group for statistical analysis. A 2-way between-groups analysis of variance revealed a significant main effect of BMI on disinhibition (P = .003) and hunger (P = .041) with higher levels found in overweight males compared to healthy-weight counterparts. A significant main effect of age on hunger (P = .046) demonstrated older males were less susceptible to hunger than younger males. These insights provide a better understanding of eating behavior across the male life cycle and may assist health professionals to better guide men in weight management in the light of rising overweight/obesity. (c) 2009 Elsevier Inc. All rights reserved
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Plasma Membrane-Associated Restriction Factors and Their Counteraction by HIV-1 Accessory Proteins.
The plasma membrane is a site of conflict between host defenses and many viruses. One aspect of this conflict is the host's attempt to eliminate infected cells using innate and adaptive cell-mediated immune mechanisms that recognize features of the plasma membrane characteristic of viral infection. Another is the expression of plasma membrane-associated proteins, so-called restriction factors, which inhibit enveloped virions directly. HIV-1 encodes two countermeasures to these host defenses: The membrane-associated accessory proteins Vpu and Nef. In addition to inhibiting cell-mediated immune-surveillance, Vpu and Nef counteract membrane-associated restriction factors. These include BST-2, which traps newly formed virions at the plasma membrane unless counteracted by Vpu, and SERINC5, which decreases the infectivity of virions unless counteracted by Nef. Here we review key features of these two antiviral proteins, and we review Vpu and Nef, which deplete them from the plasma membrane by co-opting specific cellular proteins and pathways of membrane trafficking and protein-degradation. We also discuss other plasma membrane proteins modulated by HIV-1, particularly CD4, which, if not opposed in infected cells by Vpu and Nef, inhibits viral infectivity and increases the sensitivity of the viral envelope glycoprotein to host immunity
Absence of a structural glass phase in a monoatomic model liquid predicted to undergo an ideal glass transition
We study numerically a monodisperse model of interacting classical particles
predicted to exhibit a static liquid-glass transition. Using a dynamical Monte
Carlo method we show that the model does not freeze into a glassy phase at low
temperatures. Instead, depending on the choice of the hard-core radius for the
particles the system either collapses trivially or a polycrystalline hexagonal
structure emerges.Comment: 4 pages, 4 figures, minor changes in introduction and conclusions,
additional reference
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