3,223 research outputs found
Wave scattering and splitting by magnetic metamaterials
We study experimentally propagation of electromagnetic waves
through a slab of uniaxial magnetic metamaterial. We observe a range of
novel phenomena including partial focusing and splitting into multiple
transmitted beams.We demonstrate that while some of these experimentally
observed effects can be described within the approximation of an effective
medium, a deeper understanding of the experimental results requires a
rigorous study of internal eigenmodes of the lattice of resonators
Cryptococcal choroiditis in advanced AIDS with clinicopathologic correlation.
PurposeTo describe a case of disseminated cryptococcal meningitis with multifocal choroiditis and provide optical coherence tomography (OCT) findings correlated with described histopathology in a patient with advanced acquired immunodeficiency syndrome (AIDS).ObservationsThe patient was a 54-year-old man with AIDS who presented with dyspnea and headache followed by acute vision loss. OCT demonstrated a lesion with a small area of fluid that was limited by a more prominent and irregular external limiting membrane with underlying nodular choroidal thickening, mild RPE disorganization, and hyperreflectivity of the overlying photoreceptor layer. Patient was found to have disseminated cryptococcal infection and passed away despite aggressive therapy. Autopsy was performed including bilateral enucleation and a Cryptococcus lesion was confirmed on histopathology.Conclusion and importanceThis case highlights the clinical, imaging, and histopathologic findings of cryptococcal choroiditis and provides a review of the updated treatment recommendations for disseminated infection in a patient with advanced AIDS. Although currently fundoscopy has proven most useful in directing the diagnostic algorithm in choroiditis in the setting of advanced immunosuppression, OCT may provide insight into the spread of Cryptococcus within the eye
A Trial-by-Trial Window into Sensorimotor Transformations in the Human Motor Periphery.
UNLABELLED: The appearance of a novel visual stimulus generates a rapid stimulus-locked response (SLR) in the motor periphery within 100 ms of stimulus onset. Here, we recorded SLRs from an upper limb muscle while humans reached toward (pro-reach) or away (anti-reach) from a visual stimulus. The SLR on anti-reaches encoded the location of the visual stimulus rather than the movement goal. Further, SLR magnitude was attenuated when subjects reached away from rather than toward the visual stimulus. Remarkably, SLR magnitudes also correlated with reaction times on both pro-reaches and anti-reaches, but did so in opposite ways: larger SLRs preceded shorter latency pro-reaches but longer latency anti-reaches. Although converging evidence suggests that the SLR is relayed via a tectoreticulospinal pathway, our results show that task-related signals modulate visual signals feeding into this pathway. The SLR therefore provides a trial-by-trial window into how visual information is integrated with cognitive control in humans.
SIGNIFICANCE STATEMENT: The presentation of a visual stimulus elicits a trial-by-trial stimulus-locked response (SLR) on the human limb within 100 ms. Here, we show that the SLR continues to reflect stimulus location even when subjects move in the opposite direction (an anti-reach). Remarkably, the attenuation of SLR magnitude reflected the cognitive control required to generate a correct anti-reach, with greater degrees of attenuation preceding shorter-latency anti-reaches and no attenuation preceding error trials. Our results are strikingly similar to neurophysiological recordings in the superior colliculus of nonhuman primates generating anti-saccades, implicating the tectoreticulospinal pathway. Measuring SLR magnitude therefore provides an unprecedented trial-by-trial opportunity to assess the influence of cognitive control on the initial processing of a visual stimulus in humans
Submillimetre observations of WISE-selected high-redshift, luminous, dusty galaxies
We present SCUBA-2 850um submillimetre (submm) observations of the fields of
10 dusty, luminous galaxies at z ~ 1.7 - 4.6, detected at 12um and/or 22um by
the WISE all-sky survey, but faint or undetected at 3.4um and 4.6um; dubbed
hot, dust-obscured galaxies (Hot DOGs). The six detected targets all have total
infrared luminosities greater than 10^13 L_sun, with one greater than 10^14
L_sun. Their spectral energy distributions (SEDs) are very blue from
mid-infrared to submm wavelengths and not well fitted by standard AGN SED
templates, without adding extra dust extinction to fit the WISE 3.4um and 4.6um
data. The SCUBA-2 850um observations confirm that the Hot DOGs have less cold
and/or more warm dust emission than standard AGN templates, and limit an
underlying extended spiral or ULIRG-type galaxy to contribute less than about
2% or 55% of the typical total Hot DOG IR luminosity, respectively. The two
most distant and luminous targets have similar observed submm to mid-infrared
ratios to the rest, and thus appear to have even hotter SEDs. The number of
serendipitous submm galaxies (SMGs) detected in the 1.5-arcmin-radius SCUBA-2
850um maps indicates there is a significant over-density of serendipitous
sources around Hot DOGs. These submm observations confirm that the
WISE-selected ultra-luminous galaxies have very blue mid-infrared to submm
SEDs, suggesting that they contain very powerful AGN, and are apparently
located in unusual arcmin-scale overdensities of very luminous dusty galaxies.Comment: 12 pages, 8 figures, 3 tables, accepted for publication in MNRA
A New Population of High-z, Dusty Lyα Emitters and Blobs Discovered by WISE: Feedback Caught in the Act?
By combining data from the NASA Wide-field Infrared Survey Explorer (WISE) mission with optical spectroscopy from the W. M. Keck telescope, we discover a mid-IR color criterion that yields a 78% success rate in identifying rare, typically radio-quiet, 1.6 ≾ z ≾ 4.6 dusty Lyα emitters (LAEs). Of these, at least 37% have emission extended on scales of 30-100 kpc and are considered Lyα "blobs" (LABs). The objects have a surface density of only ~0.1 deg^(–2), making them rare enough that they have been largely missed in deep, small area surveys. We measured spectroscopic redshifts for 92 of these galaxies, and find that the LAEs (LABs) have a median redshift of 2.3 (2.5). The WISE photometry coupled with data from Herschel (Herschel is an ESA space observatory with science instruments provided by European-led Principal Investigator consortia and with important participation from NASA) reveals that these galaxies are in the Hyper Luminous IR galaxy regime (L IR ≳ 10^(13)-10^(14) L_☉) and have warm colors. They are typically more luminous and warmer than other dusty, z ~ 2 populations such as submillimeter-selected galaxies and dust-obscured galaxies. These traits are commonly associated with the dust being illuminated by intense active galactic nucleus activity. We hypothesize that the combination of spatially extended Lyα, large amounts of warm IR-luminous dust, and rarity (implying a short-lived phase) can be explained if the galaxies are undergoing brief, intense "feedback" transforming them from an extreme dusty starburst/QSO into a mature galaxy
Interferometric Follow-Up of WISE Hyper-Luminous Hot, Dust-Obscured Galaxies
WISE has discovered an extraordinary population of hyper-luminous dusty
galaxies which are faint in the two bluer passbands (m and m) but are bright in the two redder passbands of WISE (m and
m). We report on initial follow-up observations of three of these
hot, dust-obscured galaxies, or Hot DOGs, using the CARMA and SMA
interferometer arrays at submm/mm wavelengths. We report continuum detections
at 1.3 mm of two sources (WISE J014946.17+235014.5 and WISE
J223810.20+265319.7, hereafter W0149+2350 and W2238+2653, respectively), and
upper limits to CO line emission at 3 mm in the observed frame for two sources
(W0149+2350 and WISE J181417.29+341224.8, hereafter W1814+3412). The 1.3 mm
continuum images have a resolution of 1-2 arcsec and are consistent with single
point sources. We estimate the masses of cold dust are 2.0 for W0149+2350 and 3.9 for W2238+2653,
comparable to cold dust masses of luminous quasars. We obtain 2 upper
limits to the molecular gas masses traced by CO, which are 3.3 and 2.3 for W0149+2350 and W1814+3412,
respectively. We also present high-resolution, near-IR imaging with WFC3 on the
Hubble Space Telescope for W0149+2653 and with NIRC2 on Keck for W2238+2653.
The near-IR images show morphological structure dominated by a single,
centrally condensed source with effective radius less than 4 kpc. No signs of
gravitational lensing are evident.Comment: 13 pages, 3 figures. ApJ in pres
Mid-infrared Selection of Active Galactic Nuclei with the Wide-Field Infrared Survey Explorer. I. Characterizing WISE-selected Active Galactic Nuclei in COSMOS
The Wide-field Infrared Survey Explorer (WISE) is an extremely capable and efficient black hole finder. We present a simple mid-infrared color criterion, W1 – W2 ≥ 0.8 (i.e., [3.4]–[4.6] ≥0.8, Vega), which identifies 61.9 ± 5.4 active galactic nucleus (AGN) candidates per deg^2 to a depth of W2 ~ 15.0. This implies a much larger census of luminous AGNs than found by typical wide-area surveys, attributable to the fact that mid-infrared selection identifies both unobscured (type 1) and obscured (type 2) AGNs. Optical and soft X-ray surveys alone are highly biased toward only unobscured AGNs, while this simple WISE selection likely identifies even heavily obscured, Compton-thick AGNs. Using deep, public data in the COSMOS field, we explore the properties of WISE-selected AGN candidates. At the mid-infrared depth considered, 160 μJy at 4.6 μm, this simple criterion identifies 78% of Spitzer mid-infrared AGN candidates according to the criteria of Stern et al. and the reliability is 95%. We explore the demographics, multiwavelength properties and redshift distribution of WISE-selected AGN candidates in the COSMOS field
Eddington-Limited Accretion in z~2 WISE-selected Hot, Dust-Obscured Galaxies
Hot, Dust-Obscured Galaxies, or "Hot DOGs", are a rare, dusty, hyperluminous
galaxy population discovered by the WISE mission. Predominantly at redshifts
2-3, they include the most luminous known galaxies in the universe. Their high
luminosities likely come from accretion onto highly obscured super massive
black holes (SMBHs). We have conducted a pilot survey to measure the SMBH
masses of five z~2 Hot DOGs via broad H_alpha emission lines, using
Keck/MOSFIRE and Gemini/FLAMINGOS-2. We detect broad H_alpha emission in all
five Hot DOGs. We find substantial corresponding SMBH masses for these Hot DOGs
(~ 10^{9} M_sun), and their derived Eddington ratios are close to unity. These
z~2 Hot DOGs are the most luminous AGNs at given BH masses, suggesting they are
accreting at the maximum rates for their BHs. A similar property is found for
known z~6 quasars. Our results are consistent with scenarios in which Hot DOGs
represent a transitional, high-accretion phase between obscured and unobscured
quasars. Hot DOGs may mark a special evolutionary stage before the red quasar
and optical quasar phases, and they may be present at other cosmic epochs.Comment: 15 pages, 9 figures. Accepted by Ap
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