A schematic illustration of the participant selection process that was used in the present study.

<p>Of a total of 1,125,691 participants, The neck dissection participants were matched 1:4 with the control group. Finally, 1,041 neck dissection participants and 4,164 control participants were included.</p

Crude and adjusted hazard ratios (95% confidence interval) of neck dissection for ischemic stroke.

<p>Crude and adjusted hazard ratios (95% confidence interval) of neck dissection for ischemic stroke.</p

General characteristics of participants.

<p>General characteristics of participants.</p

Neck dissection does not increases the risk of stroke in thyroid cancer: A national cohort study

<div><p>Objectives</p><p>The purpose of this study is to evaluate the risk of stroke (hemorrhagic or ischemic) after neck dissection in thyroid cancer patients in Korea using national cohort data.</p><p>Methods</p><p>Using the national cohort study from the Korean Health Insurance Review and Assessment Service, patients with neck dissection for thyroid cancer (1,041) and control participants (4,164) were selected and matched 1:4 (age, gender, income, and region of residence). The Chi-square test, Fischer’s exact test, and the Cox-proportional hazard model were used. The Cox-proportional analysis used a crude model and an adjusted model for age, gender, income, region of residence, hypertension, diabetes, dyslipidemia.</p><p>Results</p><p>None of the participants had suffered hemorrhagic stroke in the neck dissection group, while 0.3% (13/4,164) of participants had suffered hemorrhagic stroke in the control group (P = 0.085). In total, 0.8% (8/1,041) of participants had suffered an ischemic stroke in the neck dissection group, and 0.7% (31/4,133) of participants had suffered an ischemic stroke in the control group (P = 0.936). The adjusted hazard ratio for ischemic stroke after neck dissection was 1.06 (95% confidence interval [CI] = 0.49–2.31, P = 0.884).</p><p>Conclusion</p><p>The risk of hemorrhagic or ischemic stroke was not higher in thyroid cancer patients who underwent neck dissection than that in the matched control group.</p></div

The cumulative probability of ischemic stroke in the neck dissection and control group.

<p>The cumulative probability of ischemic stroke in the neck dissection and control group.</p

The rate of hemorrhage and ischemic stroke after neck dissection for thyroid cancer.

<p>The rate of hemorrhage and ischemic stroke after neck dissection for thyroid cancer.</p

General characteristics of participants.

<p>General characteristics of participants.</p

A schematic illustration of the participant selection process used in the present study.

<p>Of a total of 1,025,340 participants, 5,695 tonsillectomy participants were selected. Individuals who underwent a tonsillectomy for malignancy were excluded (n = 44). Tonsillectomy participants with a history of pre-operative deep neck infection were excluded (n = 84). The tonsillectomy participants were matched 1:4 with a control group that had not undergone a tonsillectomy. Unmatched tonsillectomy participants were excluded (n = 268). Ultimately, 5,299 tonsillectomy participants and 21,196 control participants were included.</p

Comparison of clinical manifestations in mpox patients living with HIV versus without HIV: a systematic review and meta-analysis

Currently, many cases of mpox patients living with the human immunodeficiency virus (HIV) have been reported. Immunocompromised mpox patients, including those living with HIV are noted for an increased risk for severe symptoms; however, existing studies did not focus on the statistical comparison of mpox outcomes associated with HIV. Thus, we conducted a systematic review and meta-analysis to evaluate and compare the clinical manifestations of mpox in people living with HIV (PLWH) and people without HIV. In this systematic review and meta-analysis, PubMed/MEDLINE, Embase, and Google Scholar were searched up to March 7, 2023. A random effects model was used to calculate the pooled prevalence along with the 95% confidence intervals (CI), and the odds ratio and its corresponding 95% CIs were calculated to elucidate the significance of each clinical feature for mpox patients with and without HIV. In this study, we included 99 published papers with 2413 patients with mpox (median age, 35.5 years; PLWH n = 1151) from 27 countries across six continents. The odds ratio of the mpox outcomes with PLWH in comparison to patients without HIV was found to be significant for skin rash (1.24, 95% CI: 1.01–1.53), proctitis (2.03, 95% CI: 1.36–3.04), cough (0.57, 95% CI: 0.33–0.98), and diarrhea (3.85, 95% CI: 1.24–11.98). The odds ratio of mpox patients with HIV for historical infections of syphilis was 2.14 (95% CI: 1.38–3.32), compared with those without HIV. This is the first international and comprehensive study that performed a systematic review and meta-analysis to statistically measure mpox manifestations according to HIV status. As clinical features related to mucosal contact were characteristically pronounced in PLWH, our systematic review provides insight that the primary invasion site of infection strongly relates to the outcomes of mpox

Long-term autoimmune inflammatory rheumatic outcomes of COVID-19: a binational cohort study

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