6 research outputs found

    The G0 Experiment: Apparatus for Parity-Violating Electron Scattering Measurements at Forward and Backward Angles

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    In the G0 experiment, performed at Jefferson Lab, the parity-violating elastic scattering of electrons from protons and quasi-elastic scattering from deuterons is measured in order to determine the neutral weak currents of the nucleon. Asymmetries as small as 1 part per million in the scattering of a polarized electron beam are determined using a dedicated apparatus. It consists of specialized beam-monitoring and control systems, a cryogenic hydrogen (or deuterium) target, and a superconducting, toroidal magnetic spectrometer equipped with plastic scintillation and aerogel Cerenkov detectors, as well as fast readout electronics for the measurement of individual events. The overall design and performance of this experimental system is discussed.Comment: Submitted to Nuclear Instruments and Method

    Aspergillus nidulans Septin AspB Plays Pre- and Postmitotic Roles in Septum, Branch, and Conidiophore Development

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    Members of the septin family of proteins act as organizational scaffolds in areas of cell division and new growth in a variety of organisms. Herein, we show that in the filamentous fungus Aspergillus nidulans, the septin AspB is important for cellular division, branching, and conidiation both pre- and postmitotically. AspB localizes postmitotically to the septation site with an underlying polarity that is evident as cytokinesis progresses. This localization at the septation site is dependent on actin and occurs before the cross-wall is visible. AspB localizes premitotically as a ring at sites of branching and secondary germ tube emergence. It is the only known branch site marker. In addition, AspB is found at several stages during the development of the asexual reproductive structure, the conidiophore. It localizes transiently to the vesicle/metula and metula/phialide interfaces, and persistently to the phialide/conidiospore interface. A temperature-sensitive mutant of AspB shows phenotypic abnormalities, including irregular septa, high numbers of branches, and immature asexual reproductive structures

    The G0 experiment: Apparatus for parity-violating electron scattering measurements at forward and backward angles

    No full text
    In the G0 experiment, performed at Jefferson Lab, the parity-violating elastic scattering of electrons from protons and quasi-elastic scattering from deuterons is measured in order to determine the neutral weak currents of the nucleon. Asymmetries as small as 1 part-per-million in the scattering of a polarized electron beam are determined using a dedicated apparatus. It consists of specialized beam monitoring and control systems, a cryogenic hydrogen (or deuterium) target, and a superconducting, toroidal magnetic spectrometer equipped with plastic scintillation and aerogel Cherenkov detectors, as well as fast readout electronics for the measurement of individual events. The overall design and performance of this experimental system is discussed. © 2011 Elsevier B.V. All rights reserved.Articl

    Inosine-5′-Monophosphate Dehydrogenase Is a Rate-determining Factor for p53-dependent Growth Regulation

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