Blockchain application in circular marine plastic debris management

The threat to the environment and humanity caused by marine plastic debris has aroused global attention. This research aims to explore the feasibility of applying blockchain technology (BCT) in marine plastic debris management. A case study on three pioneer recycling organizations is conducted based on secondary data. The study found that BCT can be applied to solve some of the existing challenges of marine plastic debris management. A digital token system and identity recognition mechanism based on BCT can increase the public awareness for marine plastic debris governance. The derived digital wallets and distributed ledgers can effectively replace paper documents and cash transactions in the traditional recycling chain, and minimize global impact on local economies, thus improve efficiency and safety. Also, the traceability and high transparency of blockchain and the application of smart contracts can effectively build a global recycling network. In addition, the application of BCT can greatly improve the transparency of recycling value chains, and make them more accepting of supervision from society and consumers. This research is one of the first studies on BCT in marine plastic debris management and explores worldwide pioneering companies. In practice, this study can help companies analyse the defects in their own waste disposal models and help practitioners make decisions to adopt BCT. In academia, as one of the early exploratory studies on the application of BCT to the treatment of marine plastic debris, this study provides further empirical reference on BCT based business models and recycling chains, and can guide future research in this field

Mesenchymal stem cells alleviate bacteria‐induced liver injury in mice by inducing regulatory dendritic cells

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/102718/1/hep26670.pd

BRI1 EMS SUPPRESSOR1 genes regulate abiotic stress and anther development in wheat (Triticum aestivum L.)

BRI1 EMS SUPPRESSOR1 (BES1) family members are crucial downstream regulators that positively mediate brassinosteroid signaling, playing vital roles in the regulation of plant stress responses and anther development in Arabidopsis. Importantly, the expression profiles of wheat (Triticum aestivum L.) BES1 genes have not been analyzed comprehensively and systematically in response to abiotic stress or during anther development. In this study, we identified 23 BES1-like genes in common wheat, which were unevenly distributed on 17 out of 21 wheat chromosomes. Phylogenetic analysis clustered the BES1 genes into four major clades; moreover, TaBES1-3A2, TaBES1-3B2 and TaBES1-3D2 belonged to the same clade as Arabidopsis BES1/BZR1 HOMOLOG3 (BEH3) and BEH4, which participate in anther development. The expression levels of 23 wheat BES1 genes were assessed using real-time quantitative PCR under various abiotic stress conditions (drought, salt, heat, and cold), and we found that most TaBES1-like genes were downregulated under abiotic stress, particularly during drought stress. We therefore used drought-tolerant and drought-sensitive wheat cultivars to explore TaBES1 expression patterns under drought stress. TaBES1-3B2 and TaBES1-3D2 expression was high in drought-tolerant cultivars but substantially repressed in drought-sensitive cultivars, while TaBES1-6D presented an opposite pattern. Among genes preferentially expressed in anthers, TaBES1-3B2 and TaBES1-3D2 expression was substantially downregulated in thermosensitive genic male-sterile wheat lines compared to common wheat cultivar under sterile conditions, while we detected no obvious differences under fertile conditions. This result suggests that TaBES1-3B2 and TaBES1-3D2 might not only play roles in regulating drought tolerance, but also participate in low temperature-induced male sterility

Vitamin B12 Levels in Methamphetamine Addicts

Objective: It has been established that reduced vitamin B12 serum levels are associated with cognitive decline and mental illness. The chronic use of methamphetamine (MA), which is a highly addictive drug, can induce cognitive impairment and psychopathological symptoms. There are few studies addressing the association of MA with vitamin B12 serum levels. This study examined whether the serum levels of B12 are associated with MA addiction.Methods: Serum vitamin B12, homocysteine (Hcy), glucose and triglyceride concentrations were measured in 123 MA addicts and 108 controls. In addition, data were collected on their age, marital status, level of education and Body Mass Index (BMI) for all participants. In the patient group, the data for each subject were collected using the Fagerstrom Test for Nicotine Dependence (FTND), the Alcohol Use Disorders Identification Test (AUDIT), and a drug use history, which included the age of onset, total duration of MA use, the number of relapses and addiction severity.Results: Our results showed that MA addicts had lower vitamin B12 levels (p < 0.05) than those of healthy controls, but Hcy levels were not significantly different between the two groups (p > 0.05). Serum B12 levels were negatively correlated with the number of relapses in the MA group. Furthermore, binary logistics regression analysis indicated that the B12 was an influencing factor contributing to addiction severity.Conclusion: The findings of this study suggest that some MA addicts might have vitamin B12 deficiency, and serum B12 levels may be involved in the prognosis of MA addiction

Editor\u27s Notes, Chiba Medical Journal 90-1

Multiple sequence alignment of deduced amino acid sequences of 25 wheat annexin genes with rice annexin OsAnn2 (Os05g31760) obtained by ClustalW. (PDF 212 kb

Artificial intelligence : A powerful paradigm for scientific research

Y Artificial intelligence (AI) coupled with promising machine learning (ML) techniques well known from computer science is broadly affecting many aspects of various fields including science and technology, industry, and even our day-to-day life. The ML techniques have been developed to analyze high-throughput data with a view to obtaining useful insights, categorizing, predicting, and making evidence-based decisions in novel ways, which will promote the growth of novel applications and fuel the sustainable booming of AI. This paper undertakes a comprehensive survey on the development and application of AI in different aspects of fundamental sciences, including information science, mathematics, medical science, materials science, geoscience, life science, physics, and chemistry. The challenges that each discipline of science meets, and the potentials of AI techniques to handle these challenges, are discussed in detail. Moreover, we shed light on new research trends entailing the integration of AI into each scientific discipline. The aim of this paper is to provide a broad research guideline on fundamental sciences with potential infusion of AI, to help motivate researchers to deeply understand the state-of-the-art applications of AI-based fundamental sciences, and thereby to help promote the continuous development of these fundamental sciences.Peer reviewe

Predicting Possible New Links to Future Global Plastic Waste Trade Networks

China’s waste plastic ban has sparked a discussion about how the global plastic waste trade (GPWT) will develop in the future. To answer this question, this article uses the link forecasting and QAP method to predict and analyze the possible development trend of the GPWT in the future. The research results show that GPWT has certain stability and sustainability; although plastic waste trade has narrowed under the ban, it still has the potential trend of reconnecting the same type of links. Specifically, from a regional perspective, the future trade of new plastic waste trade will be dominated by cross-regional trade. Plastic waste may continue to flow to countries in the Asian–Pacific, Middle East, and African regions, while European countries will strengthen the internal recycling and processing of plastic waste. From the perspective of the national income level, the establishment of the new relationship will show an evolutionary trend in which high-income countries are dominated and the scale of trade between non-high-income countries expands. In addition, the differences in the level of economic development, liner transport connectivity, and the proportion of mismanagement of plastic waste among countries has a positive effect on the establishment of a new relationship in the GPWT, while tariff rates have an inhibitory effect. In general, the GPWT will still exist in the future, which requires the international community to guide the GPWT to promote the recycling and reuse of plastic waste in a real sense and adjust the unreasonable trade model