Inflation in de Sitter spacetime and CMB large scales anomaly

The influence of cosmological constant type dark energy in the early universe is investigated. This is accommodated by a new dispersion relation in de Sitter spacetime. We perform a global fitting to explore the cosmological parameters space by using the CosmoMC package with the recently released Planck TT and WMAP Polarization datasets. Using the results from global fitting, we compute a new CMB temperature-temperature spectrum. The obtained TT spectrum has lower power compared with the one based on $\Lambda$CDM model at large scales.Comment: 4 pages, 1 table, 3 figure

The evolution of magnetic structure driven by a synthetic spin-orbit coupling in two-component Bose-Hubbard model

We study the evolution of magnetic structure driven by a synthetic spin-orbit coupling in a one-dimensional two-component Bose-Hubbard model. In addition to the Mott insulator-superfluid transition, we found in Mott insulator phases a transition from a gapped ferromagnetic phase to a gapless chiral phase by increasing the strength of spin-orbit coupling. Further increasing the spin-orbit coupling drives a transition from the gapless chiral phase to a gapped antiferromagnetic phase. These magnetic structures persist in superfluid phases. In particular, in the chiral Mott insulator and chiral superfluid phases, incommensurability is observed in characteristic correlation functions. These unconventional Mott insulator phase and superfluid phase demonstrate the novel effects arising from the competition between the kinetic energy and the spin-orbit coupling.Comment: 9 fig; English polished, note adde

Further Study On U(1) Gauge Invariance Restoration

To further investigate the applicability of the projection scheme for eliminating the unphysical divergence $s/m_e^2$ due to U(1) gauge invariance violation, we study the process $e^-+W^+\to e^-+\bar t+b$ which possesses advantages of simplicity and clearness. Our study indicates that the projection scheme can indeed eliminate the unphysical divergence $s/m_e^2$ caused by the U(1) gauge invariance violation and the scheme can apply to very high energy region.Comment: Latex, 13 pages, 4 EPS fiure

Building quantum neural networks based on swap test

Artificial neural network, consisting of many neurons in different layers, is an important method to simulate humain brain. Usually, one neuron has two operations: one is linear, the other is nonlinear. The linear operation is inner product and the nonlinear operation is represented by an activation function. In this work, we introduce a kind of quantum neuron whose inputs and outputs are quantum states. The inner product and activation operator of the quantum neurons can be realized by quantum circuits. Based on the quantum neuron, we propose a model of quantum neural network in which the weights between neurons are all quantum states. We also construct a quantum circuit to realize this quantum neural network model. A learning algorithm is proposed meanwhile. We show the validity of learning algorithm theoretically and demonstrate the potential of the quantum neural network numerically.Comment: 10 pages, 13 figure

Vector Dissipative Solitons in Graphene Mode Locked Fiber Lasers

Vector soliton operation of erbium-doped fiber lasers mode locked with atomic layer graphene was experimentally investigated. Either the polarization rotation or polarization locked vector dissipative solitons were experimentally obtained in a dispersion-managed cavity fiber laser with large net cavity dispersion, while in the anomalous dispersion cavity fiber laser, the phase locked NLSE solitons and induced NLSE soliton were experimentally observed. The vector soliton operation of the fiber lasers unambiguously confirms the polarization insensitive saturable absorption of the atomic layer graphene when the light is incident perpendicular to its 2D atomic layer

Catalase Prevents Maternal Diabetes–Induced Perinatal Programming via the Nrf2–HO-1 Defense System

We investigated whether overexpression of catalase (CAT) in renal proximal tubular cells (RPTCs) could prevent the programming of hypertension and kidney disease in the offspring of dams with maternal diabetes. Male offspring of nondiabetic and diabetic dams from two transgenic (Tg) lines (Hoxb7-green fluorescent protein [GFP]-Tg [controls] and Hoxb7/CAT-GFP-Tg, which overexpress CAT in RPTCs) were studied from the prenatal period into adulthood. Nephrogenesis, systolic blood pressure, renal hyperfiltration, kidney injury, and reactive oxygen species (ROS) generation were assessed. Gene expression of transforming growth factor-β1 (TGF-β1), nuclear factor erythroid 2p45–related factor-2 (Nrf2), and heme oxygenase-1 (HO-1) was tested in both in vitro and in vivo studies. Renal dysmorphogenesis was observed in offspring of Hoxb7-GFP-Tg dams with severe maternal diabetes; the affected male offspring displayed higher renal ROS generation and developed hypertension and renal hyperfiltration as well as renal injury with heightened TGF-β1 expression in adulthood. These changes were ameliorated in male offspring of diabetic Hoxb7/CAT-GFP-Tg dams via the Nrf2–HO-1 defense system. CAT promoted Nrf2 nuclear translocation and HO-1 gene expression, seen in both in vitro and in vivo studies. In conclusion, CAT overexpression in the RPTCs ameliorated maternal diabetes–induced perinatal programming, mediated, at least in part, by triggering the Nrf2–HO-1 defense system

Non-traditional CD4+CD25−CD69+ regulatory T cells are correlated to leukemia relapse after allogeneic hematopoietic stem cell transplantation

Background: Non-traditional CD4+CD25-CD69+ T cells were found to be involved in disease progression in tumor-bearing mouse models and cancer patients recently. We attempted to define whether this subset of T cells were related to leukemia relapse after allogeneic hematopoietic cell transplantation (allo-HSCT). Methods: The frequency of CD4+CD25-CD69+ T cells among the CD4+ T cell population from the bone marrow of relapsed patients, patients with positive minimal residual disease (MRD+) and healthy donors was examined by flow cytometry. The CD4+CD25-CD69+ T cells were also stained with the intracellular markers to determine the cytokine (TGF-beta, IL-2 and IL-10) secretion. Results: The results showed that the frequency of CD4+CD25-CD69 + T cells was markedly increased in patients in the relapsed group and the MRD + group compared to the healthy donor group. The percentage of this subset of T cells was significantly decreased after effective intervention treatment. We also analyzed the reconstitution of CD4+CD25-CD69+ T cells at various time points after allo-HSCT, and the results showed that this subset of T cells reconstituted rapidly and reached a relatively higher level at +60 d in patients compared to controls. The incidence of either MRD+ or relapse in patients with a high frequency of CD4+CD25-CD69+ T cells (>7%) was significantly higher than that of patients with a low frequency of CD4+CD25-CD69+ T cells at +60 d, +90 d and +270 d after transplant. However, our preliminary data indicated that CD4+CD25-CD69+ T cells may not exert immunoregulatory function via cytokine secretion. Conclusions: This study provides the first clinical evidence of a correlation between non-traditional CD4+CD25-CD69+ Tregs and leukemia relapse after allo-HSCT and suggests that exploration of new methods of adoptive immunotherapy may be beneficial. Further research related to regulatory mechanism behind this phenomenon would be necessary.Medicine, Research & ExperimentalSCI(E)[email protected]