EFFECT OF KNEE TAPING ON THE KNEE KINEMATICS DURING LEVEL WALKING

The purpose of this study was to investigate the effect of knee taping on the knee kinematics during level walking. Fifteen healthy subjects participated in this study. Vicon Nexus motion analysis system was used. Reflective markers were placed on anatomical landmarks to compute the kinematics during level walking. Knee joint angle and range of motion were analyzed. Paired t test was used to compare the differences between no taping and knee taping. The results showed that the knee taping would increase the external rotation and decrease the internal rotation of the knee joint during level walking. Knee taping would decrease the adduction angle and the range of motion in the frontal plane during level walking compared to no taping. It is suggested that knee taping can be used for the people with ACL insufficiency to enhance the knee stability

Building quantum neural networks based on swap test

Artificial neural network, consisting of many neurons in different layers, is an important method to simulate humain brain. Usually, one neuron has two operations: one is linear, the other is nonlinear. The linear operation is inner product and the nonlinear operation is represented by an activation function. In this work, we introduce a kind of quantum neuron whose inputs and outputs are quantum states. The inner product and activation operator of the quantum neurons can be realized by quantum circuits. Based on the quantum neuron, we propose a model of quantum neural network in which the weights between neurons are all quantum states. We also construct a quantum circuit to realize this quantum neural network model. A learning algorithm is proposed meanwhile. We show the validity of learning algorithm theoretically and demonstrate the potential of the quantum neural network numerically.Comment: 10 pages, 13 figure

The Pseudorabies Virus DNA Polymerase Accessory Subunit UL42 Directs Nuclear Transport of the Holoenzyme

Pseudorabies virus (PRV) DNA replication occurs in the nuclei of infected cells and requires the viral DNA polymerase. The PRV DNA polymerase comprises a catalytic subunit, UL30, and an accessory subunit, UL42, that confers processivity to the enzyme. Its nuclear localization is a prerequisite for its enzymatic function in the initiation of viral DNA replication. However, the mechanisms by which the PRV DNA polymerase holoenzyme enters the nucleus have not been determined. In this study, we characterized the nuclear import pathways of the PRV DNA polymerase catalytic and accessory subunits. Immunofluorescence analysis showed that UL42 localizes independently in the nucleus, whereas UL30 alone predominantly localizes in the cytoplasm. Intriguingly, the localization of UL30 was completely shifted to the nucleus when it was coexpressed with UL42, demonstrating that nuclear transport of UL30 occurs in an UL42-dependent manner. Deletion analysis and site-directed mutagenesis of the two proteins showed that UL42 contains a functional and transferable bipartite nuclear localization signal (NLS) at amino acids 354–370 and that K354, R355, and K367 are important for the NLS function, whereas UL30 has no NLS. Coimmunoprecipitation assays verified that UL42 interacts with importins α3 and α4 through its NLS. In vitro nuclear import assays demonstrated that nuclear accumulation of UL42 is a temperature- and energy-dependent process and requires both importins α and β, confirming that UL42 utilizes the importin α/β-mediated pathway for nuclear entry. In an UL42 NLS-null mutant, the UL42/UL30 heterodimer was completely confined to the cytoplasm when UL42 was coexpressed with UL30, indicating that UL30 utilizes the NLS function of UL42 for its translocation into the nucleus. Collectively, these findings suggest that UL42 contains an importin α/β-mediated bipartite NLS that transports the viral DNA polymerase holoenzyme into the nucleus in an in vitro expression system

3-Methyl-1-(3-nitro­phen­yl)-5-phenyl-4,5-dihydro-1H-pyrazole

In the title compound, C16H15N3O2, the planar [maximum deviation 0.156 (2) Å] pyrazoline ring is nearly coplanar with the 3-nitro­phenyl group and is approximately perpendicular to the phenyl ring, making dihedral angles of 3.80 (8) and 80.58 (10)°, respectively. Weak inter­molecular C—H⋯O hydrogen bonding is present in the crystal structure

Design and Development of the Reactive BGP peering in Software-Defined Routing Exchanges

The Software-Defined Networking (SDN) is considered to be an improved solution for applying flexible control and operation recently in the network. Its characteristics include centralized management, global view, as well as fast adjustment and adaptation. Many experimental and research networks have already migrated to the SDN-enabled architecture. As the global network continues to grow in a fast pace, how to use SDN to improve the networking fields becomes a popular topic in research. One of the interesting topics is to enable routing exchanges among the SDN-enabled network and production networks. However, considering that many production networks are still operated on legacy architecture, the enabled SDN routing functionalities have to support hybrid mode in operation. In this paper, we propose a routing exchange mechanism by enabling reactive BGP peering actions among the SDN and legacy network components. The results of experiments show that our SDN controller is able to mask as an Autonomous System (AS) to exchange routing information with other BGP routers