Serum Biochemical Phenotypes in the Domestic Dog

The serum or plasma biochemical profile is essential in the diagnosis and monitoring of systemic disease in veterinary medicine, but current reference intervals typically take no account of breed-specific differences. Breed-specific hematological phenotypes have been documented in the domestic dog, but little has been published on serum biochemical phenotypes in this species. Serum biochemical profiles of dogs in which all measurements fell within the existing reference intervals were retrieved from a large veterinary database. Serum biochemical profiles from 3045 dogs were retrieved, of which 1495 had an accompanying normal glucose concentration. Sixty pure breeds plus a mixed breed control group were represented by at least 10 individuals. All analytes, except for sodium, chloride and glucose, showed variation with age. Total protein, globulin, potassium, chloride, creatinine, cholesterol, total bilirubin, ALT, CK, amylase, and lipase varied between sexes. Neutering status significantly impacted all analytes except albumin, sodium, calcium, urea, and glucose. Principal component analysis of serum biochemical data revealed 36 pure breeds with distinctive phenotypes. Furthermore, comparative analysis identified 23 breeds with significant differences from the mixed breed group in all biochemical analytes except urea and glucose. Eighteen breeds were identified by both principal component and comparative analysis. Tentative reference intervals were generated for breeds with a distinctive phenotype identified by comparative analysis and represented by at least 120 individuals. This is the first large-scale analysis of breed-specific serum biochemical phenotypes in the domestic dog and highlights potential genetic components of biochemical traits in this species

Parallel Computing on a PC Cluster

The tremendous advance in computer technology in the past decade has made it possible to achieve the performance of a supercomputer on a very small budget. We have built a multi-CPU cluster of Pentium PC capable of parallel computations using the Message Passing Interface (MPI). We will discuss the configuration, performance, and application of the cluster to our work in physics.Comment: 3 pages, uses Latex and aipproc.cl

Testing a new luminosity/redshift indicator for γ\gamma-ray bursts

We have tested a relative spectral lag (RSL) method suggested earlier as a luminosity/redshift (or distance) estimator, using the generalized method by Schaefer & Collazzi. We find the derivations from the luminosity/redshift-RSL (L/R-RSL) relation are comparable with the corresponding observations. Applying the luminosity-RSL relation to two different GRB samples, we find that there exist no violators from the generalized test, namely the Nakar & Piran test and Li test. We also find that about 36 per cent of Schaefer's sample are outliers for the L/R-RSL relation within 1$\sigma$ confidence level, but no violators at 3$\sigma$ level within the current precision of L/R-RSL relation. An analysis of several potential outliers for other luminosity relations shows they can match the L/R-RSL relation well within an acceptable uncertainty. All the coincident results seem to suggest that this relation could be a potential tool for cosmological study.Comment: 7 pages, 6 figures and 1 table; Comments are welcom

Spectrum for Heavy Quankonia and Mixture of the Relevant Wave Functions within the Framework of Bethe-Salpeter Equation

Considering the fact that some excited states of the heavy quarkonia (charmonium and bottomonium) still missing in experimental observations and potential applications of the relevant wave functions of the bound states, we re-analyze the spectrum and the relevant wave functions of the heavy quarkonia within the framework of Bethe-Salpeter (B.S.) equation with a proper QCD-inspired kernel. Such a kernel for the heavy quarkonia, relating to potential of non-relativistic quark model, is instantaneous, so we call the corresponding B.S. equation as BS-In equation throughout the paper. Particularly, a new way to solve the B.S. equation, which is different from the traditional ones, is proposed here, and with it not only the known spectrum for the heavy quarkonia is re-generated, but also an important issue is brought in, i.e., the obtained solutions of the equation `automatically' include the 'fine', 'hyperfine' splittings and the wave function mixture, such as $S-D$ wave mixing in $J^{PC}=1^{--}$ states, $P-F$ wave mixing in $J^{PC}=2^{++}$ states for charmonium and bottomonium etc. It is pointed out that the best place to test the wave mixture probably is at $Z$-factory ($e^+e^-$ collider running at $Z$-boson pole with extremely high luminosity).Comment: 26 pages, 8 figure

A tale of five fricatives: Consonantal contrast in heritage speakers of Mandarin

This study investigated the production of five Mandarin and English sibilant fricatives by heritage speakers of Mandarin in comparison to native speakers and late learners. Almost all speakers were found to distinguish the Mandarin retroflex and alveolo-palatal, as well as the Mandarin alveolo-palatal and English palato-alveolar. However, fewer distinguished the Mandarin retroflex and English palato-alveolar or the Mandarin and English alveolars, with the majority of heritage speakers falling into this group of "distinguishers" in both cases. These results indicate that heritage speakers, in addition to most late learners, do not have much trouble with the Mandarin post-alveolar contrast, and furthermore, that while native speakers and late learners of Mandarin tend to merge similar Mandarin and English sounds, heritage speakers tend to keep them apart. Thus, of the three groups heritage speakers appear to be the best at maintaining contrast between categories both within and across languages

Production of phonetic and phonological contrast by heritage speakers of Mandarin

This study tested the hypothesis that heritage speakers of a minority language, due to their childhood experience with two languages, would outperform late learners in producing contrast: language-internal phonological contrast, as well as cross-linguistic phonetic contrast between similar, yet acoustically distinct, categories of different languages. To this end, production of Mandarin and English by heritage speakers of Mandarin was compared to that of native Mandarin speakers and native American English-speaking late learners of Mandarin in three experiments. In experiment 1, back vowels in Mandarin and English were produced distinctly by all groups, but the greatest separation between similar vowels was achieved by heritage speakers. In experiment 2, Mandarin aspirated and English voiceless plosives were produced distinctly by native Mandarin speakers and heritage speakers, who both put more distance between them than late learners. In experiment 3, the Mandarin retroflex and English palato-alveolar fricatives were distinguished by more heritage speakers and late learners than native Mandarin speakers. Thus, overall the hypothesis was supported: across experiments, heritage speakers were found to be the most successful at simultaneously maintaining language-internal and cross-linguistic contrasts, a result that may stem from a close approximation of phonetic norms that occurs during early exposure to both languages

On the water-bag model of dispersionless KP hierarchy

We investigate the bi-Hamiltonian structure of the waterbag model of dKP for two component case. One can establish the third-order and first-order Hamiltonian operator associated with the waterbag model. Also, the dispersive corrections are discussed.Comment: 19 page

J/Psi Production from Electromagnetic Fragmentation in Z decay

The rate for $Z^{0}\to J/ \psi + \ell^{+}\ell^{-}$ is suprisingly large with about one event for every million $Z^{0}$ decays. The reason for this is that there is a fragmentation contribution that is not suppressed by a factor of $M^{2}_{\psi}/M^{2}_{Z}$. In the fragmentation limit $M_{Z}\to\infty$ with $E_{\psi}/M_{Z}$ fixed, the differential decay rate for $Z^{0}\to J/ \psi + \ell^{+}\ell^{-}$ factors into electromagnetic decay rates and universal fragmentation functions. The fragmentation functions for lepton fragmentation and photon fragmentation into $J/\psi$ are calculated to lowest order in $\alpha$. The fragmentation approximation to the rate is shown to match the full calculation for $E_{\psi}$ greater than about $3 M_{\psi}$.Comment: 16 pages and 8 figure