36,953 research outputs found
Power-law Behavior of High Energy String Scatterings in Compact Spaces
We calculate high energy massive scattering amplitudes of closed bosonic
string compactified on the torus. We obtain infinite linear relations among
high energy scattering amplitudes. For some kinematic regimes, we discover that
some linear relations break down and, simultaneously, the amplitudes enhance to
power-law behavior due to the space-time T-duality symmetry in the compact
direction. This result is consistent with the coexistence of the linear
relations and the softer exponential fall-off behavior of high energy string
scattering amplitudes as we pointed out prevously. It is also reminiscent of
hard (power-law) string scatterings in warped spacetime proposed by Polchinski
and Strassler.Comment: 6 pages, no figure. Talk presented by Jen-Chi Lee at Europhysics
Conference (EPS2007), Manchester, England, July 19-25, 2007. To be published
by Journal of Physics: Conference Series
Intentions and Attitudes Towards Parenthood and Fertility Awareness Among Chinese University Students in Hong Kong: A Comparison with Western Samples
STUDY QUESTION What are the levels of awareness regarding female fertility and the intentions and attitudes towards parenthood among Chinese university students in Hong Kong compared with their counterparts in the West?
SUMMARY ANSWER Chinese university students in Hong Kong were similarly over-optimistic about the age-related fertility decline, although they were less inclined to have children and undergo fertility treatment compared with their Western counterparts.
WHAT IS KNOWN ALREADY Past studies of highly educated young adults in Europe and the USA have found that they are not sufficiently aware of the age-related decline in female fertility, and falsely believe that advanced reproductive treatments such as IVF will overcome fertility problems associated with age. Little is known about the perceptions of Chinese students in Hong Kong, a modernized Chinese city where the fertility rate is among the lowest in the world.
STUDY DESIGN, SIZE, DURATION An online cross-sectional survey of Chinese university students in Hong Kong was conducted in 2013. Results were compared with two similar studies in Sweden and the USA.
PARTICIPANTS/MATERIALS, SETTING, METHODS A total of 367 university students in Hong Kong (275 female, 92 male; mean age 23) responded to an e-mail invitation to participate in an online survey. Intentions and attitudes towards parenthood and awareness regarding female fertility were assessed using the Swedish Fertility Awareness Questionnaire.
MAIN RESULTS AND THE ROLE OF CHANCE Like their Western counterparts, a large proportion of Chinese university students underestimated the age-related fertility decline (92%) and overestimated the fertility treatment success rate (66%). However, they were less inclined to have children, were more aware of and less concerned with infertility and were less motivated to seek solutions in the event of a fertility problem. These comparisons were significant at P \u3c 0.05.
LIMITATIONS, REASONS FOR CAUTION Self-selection bias was inevitable in the questionnaire survey, and the anonymous nature of the survey did not permit the collection of characteristics of non-responders. International comparisons warrant caution because the Hong Kong sample was older than the US sample (mean age 20), but not older than the Sweden sample (mean age 24).
WIDER IMPLICATION OF FINDINGS While this study was consistent with past Western studies on the lack of fertility awareness among highly educated young people, the findings reveal significant cultural differences in family planning and responses to infertility between Asia and the West
Tropospheric HO2 determination by FAGE
The detection efficiency is greatest at low pressures, where the subsequent removal of the HO product by the NO reagent (via HO + NO + M yields HONO + M) is relatively slow. Moreover, nozzle expansion of the air from ambient to low pressures produces a turbulent zone that assists in mixing the reagent with the sample. If the HO product is observed by laser-excited fluorescence, then the other advantages of low-pressure detection by FAGE (Fluorescence Assay with Gas Expansion) also apply. The FAGE instrumental response was calibrated to external HO2 by observing NO decay in the photolysis of HO-CH2O mixtures and by choosing conditions in which HO2 + NO is the only significant NO destruction path. HO2 was determined in urban air
Cosmic ray feedback in the FIRE simulations: constraining cosmic ray propagation with GeV gamma ray emission
We present the implementation and the first results of cosmic ray (CR)
feedback in the Feedback In Realistic Environments (FIRE) simulations. We
investigate CR feedback in non-cosmological simulations of dwarf, sub-
starburst, and galaxies with different propagation models, including
advection, isotropic and anisotropic diffusion, and streaming along field lines
with different transport coefficients. We simulate CR diffusion and streaming
simultaneously in galaxies with high resolution, using a two moment method. We
forward-model and compare to observations of -ray emission from nearby
and starburst galaxies. We reproduce the -ray observations of dwarf and
galaxies with constant isotropic diffusion coefficient . Advection-only and streaming-only
models produce order-of-magnitude too large -ray luminosities in dwarf
and galaxies. We show that in models that match the -ray
observations, most CRs escape low-gas-density galaxies (e.g.\ dwarfs) before
significant collisional losses, while starburst galaxies are CR proton
calorimeters. While adiabatic losses can be significant, they occur only after
CRs escape galaxies, so they are only of secondary importance for -ray
emissivities. Models where CRs are ``trapped'' in the star-forming disk have
lower star formation efficiency, but these models are ruled out by -ray
observations. For models with constant that match the -ray
observations, CRs form extended halos with scale heights of several kpc to
several tens of kpc.Comment: 31 pages, 26 figures, accepted for publication in MNRA
T-cell receptor gene expression in tumour-infiltrating lymphocytes and peripheral blood lymphocytes of patients with nasopharyngeal carcinoma.
The T-cell receptor (TCR) repertoire expression of tumour-infiltrating lymphocytes (TILs) from 19 nasopharyngeal carcinoma (NPC) biopsies was compared with those of lymphocytes from 18 control nasopharyngeal biopsies. mRNA was extracted from these lymphocytes and the cDNA transcribed. A panel of 18 V alpha- and 21 V beta-specific primers was used to detect the TCR gene use from cDNA. The use of V alpha and V beta genes was restricted in TILs compared with lymphocytes from biopsies. The frequencies of V alpha 2, V alpha 3, V alpha 9, V alpha 10, V alpha 11, V alpha 13, V alpha 14, V alpha 15, V beta 11, V beta 15 and V beta 20 were decreased and the frequencies of V alpha 10 [Pc = 0.04; relative risk (RR) = 0.05], V alpha 11 (Pc = 0.02; RR = 0.07), V alpha 13 (Pc = 0.002; RR = 0), V alpha 14 (Pc = 0.04; RR = 0.05), V beta 14 (Pc = 0.001; RR = 0.03) and V beta 20 (Pc = 0.001; RR = 0.03) remained significantly reduced after correction for the number of families typed. The frequency of V alpha 17 was higher in NPC biopsies than in NPC PBLs (P = 0.05), and the frequency of V beta 15 was lower in NPC biopsies than in NPC PBLs (P = 0.02). The frequencies of V alpha 17 and V alpha 18 in HLA-B46+ patients were significantly lower (P = 0.009; P = 0.044) than in B46+ controls. The results suggest that the restriction of TCR gene use in NPC patients may be important in NPC pathogenesis
A staged approach with vincristine, adriamycin, and dexamethasone followed by bortezomib, thalidomide, and dexamethasone before autologous hematopoietic stem cell transplantation in the treatment of newly diagnosed multiple myeloma
Bortezomib-based regimens have significant activities in multiple myeloma (MM). In this study, we tested the efficacy of a total therapy with a staged approach where newly diagnosed MM patients received vincristine/adriamycin/dexamethsone (VAD). VAD-sensitive patients (≥75% paraprotein reduction) received autologous hematopoietic stem cell transplantation (auto-HSCT), whereas less VAD-sensitive patients (<75% paraprotein reduction) received bortezomib/thalidomide/dexamethasone (VTD) for further cytoreduction prior to auto-HSCT. On an intention-to-treat analysis, a progressive increase of complete remission (CR) rates was observed, with cumulative CR rates of 48% after HSCT. Seven patients progressed leading to three fatalities, of which two had central nervous system disease. The 3-year overall survival and event-free survival were 75.1% and 48.3%, respectively. Six patients developed oligoclonal reconstitution with new paraproteins. In the absence of anticoagulant prophylaxis, no patients developed deep vein thrombosis. The staged application of VAD+/–VTD/auto-HSCT resulted in an appreciable response rate and promising survivals. Our approach reduced the use of bortezomib without compromising the ultimate CR rate and is of financial significance for less affluent communities
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