A New Model for Location-Allocation Problem within Queuing Framework

This paper proposes a bi-objective model for the facility location problem under a congestion system. The idea of the model is motivated by applications of locating servers in bank automated teller machines (ATMS), communication networks, and so on. This model can be specifically considered for situations in which fixed service facilities are congested by stochastic demand within queueing framework. We formulate this model with two perspectives simultaneously: (i) customers and (ii) service provider. The objectives of the model are to minimize (i) the total expected travelling and waiting time and (ii) the average facility idle-time. This model represents a mixed-integer nonlinear programming problem which belongs to the class of NP-hard problems. In addition, to solve the model, two metaheuristic algorithms including non-dominated sorting genetic algorithms (NSGA-II) and non-dominated ranking genetic algorithms (NRGA) are proposed. Besides, to evaluate the performance of the two algorithms some numerical examples are roduced and analyzed with some metrics to determine which algorithm works better

Genetic Algorithm and Simulated Annealing for Redundancy Allocation Problem with Cold-standby Strategy

This paper presents a new mathematical model for a redundancyallocation problem (RAP) withcold-standby redundancy strategy and multiple component choices.The applications of the proposed model arecommon in electrical power, transformation,telecommunication systems,etc.Manystudies have concentrated onone type of time-to-failure, butin thispaper, two components of time-to-failures which follow hypo-exponential and exponential distributionare investigated. The goal of the RAP is to select available components and redundancy level for each subsystem for maximizing system reliability under cost and weight constraints.Sincethe proposed model belongs to NP-hard class, we proposed two metaheuristic algorithms; namely, simulated annealing and genetic algorithm to solve it. In addition, a numerical example is presented to demonstrate the application of the proposed solution methodology.</p

Gut Microbial Flora, Prebiotics, and Probiotics in Multiple Sclerosis: Their Current Usage and Utility

International audienc

The association between a priori dietary patterns and psychological disorders in military personnel

Abstract Background Studies have identified a high prevalence of poor mental health, including depression, anxiety, and stress in military occupations. A low quality diet is one of the potential factors related to mental disorders. This study aimed to investigate the association of a priori dietary patterns, including dietary approach to stop hypertension (DASH), the Mediterranean diet (MD), dietary inflammatory index (DII), and healthy eating index-2015 (HEI-2015) with the odds of depression, anxiety, and stress in military staff. Methods This cross-sectional study was performed on a total of 400 military staff, aged 38.67 ± 5.22 (ranging from 30 to 60) years, recruited from Iranian military centers. The dietary intake of participants and adherence to the DASH, MD, DII, and HEI-2015 was measured using a 168-item food frequency questionnaire (FFQ). Mental health was evaluated with the use of the Depression, Anxiety, and Stress Scale − 21 (DASS-21). Results The prevalence of depression, anxiety, and stress was 64.5%, 63.2%, and 61.3%, respectively. Individuals with the highest adherence to HEI-2015, compared to those with the lowest adherence, were significantly at lower odds of anxiety (OR = 0.51, 95%CI: 0.27–0.96, p = 0.03), while higher adherence to DII was related to a 2.74-fold increased odds of anxiety (OR = 2.74, 95%CI: 1.06–7.04, p = 0.03). Compared to those with the lowest adherence (quartile 1), quartile 2 of the HEI-2015 was associated with decreased odds of stress (p = 0.04). No association was identified between dietary patterns and depression. Conclusion Greater adherence to HEI-2015 and lower adherence to DII are associated with lower odds of anxiety in military staff

Study Literatur Use Of Active-Assistive Range Of Motion Cylindrical Grip And Spherical Grip Towards Increasing Upper Extremity Muscle Strength In Stroke Patients (Studi Literatur Penggunaan ROM Aktif-Asistif Cylindrical Grip dan Spherical Grip Terhadap Peningkatan Kekuatan Otot Ekstremitas Atas Pada Pasien Stroke)

ABSTRACTStroke is damage to brain tissue due to disruption of blood flow to the brain. One of the effects that occur in stroke patients is weakness on one side of the body, such as the upper extremity. Exercises to stimulate movement in the hands can be in the form of active-assistive ROM cylindrical grip and spherical grip. The purpose of this research is to identify research articles that describe the use of ROM cylindrical grip and spherical grip to increase upper extremity muscle strength in stroke patients. Design this research is a literature review study. Article searches were carried out comprehensively through a database of national and international indexed research journals with the inclusion and exclusion criteria. The types of research articles are quasi experiment, pre-experimental study, and retrospective study. The research articles obtained were 11 articles, analyzed and synthesized in a tabular format. The results of the literature review is active-assisted ROM cylindrical grip and spherical grip are used as limb movement exercises in the rehabilitation process for stroke patients, namely cylindrical grip ROM, spherical grip both using simple tools (tissue rolls, baseball) as well as technological innovations that have developed such as Robot-assisted Therapy, 3D immersive virtual reality, and Hand Extension Robot Orthosis (HERO) Grip Glove. The conclusion of this study is ROM cylindrical grip and spherical grip are used as post-stroke rehabilitation exercises that are useful for training muscle strength, especially when gripping, preventing joint stiffness, as well as in carrying out daily activities. ABSTRAKStroke adalah kerusakan jaringan otak akibat terganggunya alirah darah menuju otak. Salah satu dampak yang terjadi pada pasien stroke adalah kelemahan di salah satu sisi tubuh, seperti ekstremitas atas. Latihan untuk menstimulasi gerak pada tangan dapat berupa latihan ROM aktif-asistif cylindrical grip dan spherical grip. Penelitian ini bertujuan untuk mengidentifikasi artikel-artikel penelitian yang memaparkan penggunaan latihan ROM aktif-asistif cylindrical grip dan spherical grip terhadap peningkatan kekuatan otot ekstremitas atas pada pasin stroke.Jenis penelitian kajian literatur. Pencarian artikel dilakukan secara komprehensif melalui database jurnal penelitian terindeks nasional dan internasional yang memenuhi kriteria inklusi dan eklusi. Jenis artikel penelitian yang digunakan sebagai referensi adalah quasi experiment, pre-experimental study, dan retrospective study. Artikel penelitian yang didapatkan sebanyak 11 artikel, dianalisis dan disintesis dalam format tabel. Hasil kajian literatur menunjukkan ROM aktif-asistif cylindrical grip dan spherical grip dimanfaatkan sebagai latihan gerak ekstremitas dalam proses rehabilitasi pada pasien stroke yaitu ROM cylindrical grip, spherical grip baik yang menggunakan alat sederhana (tissue gulung, bola kasti) maupun inovasi teknologi yang sudah berkembang seperti Robot-assisted Therapy, 3D immersive virtual realility, dan Hand Extension Robot Orthosis (HERO) Grip Glove. Penggunaan ROM aktif-asistif cylindrical grip dan spherical grip sebagai latihan rehabilitasi pasca stroke dimana bermanfaat untuk melatih kekuatan otot, terutama ketika mengenggam, mencegah kekakuan sendi, serta dalam melakukan aktivitas sehari-hari

ASUHAN KEPERAWATAN KELEBIHAN VOLUME CAIRAN PADA PASIEN GAGAL GINJAL KRONIK DI RSUD DR. M . ASHARI PEMALANG

Latar Belakang - Gagal Ginjal Kronik adalah suatu penurunan fungsi ginjal yang cukup berat dan terjadi secara perlahan dalam waktu yang lama disebabkan oleh berbagai penyakit ginjal, bersifat progesif dan umumnya tidak dapat pulih, dimana tubuh tidak mampu memelihara metabolisme dan gagal memelihara keseimbangan cairan.Tujuan - Memberikan gambaran asuhan keperawatan secara komprehensif pada kedua pasien Penyakit Ginjal Kronik khususnya dengan masalah keperawatan Kelebihan Volume Cairan.Metode - Metode yang digunakan adalah metode deskriptif dengan pendekatan studi kasus berupa proses asuhan keperawatan selama 3 x 24 jam terdiri dari pengkajian, diagnosa, perencanaan, tindakan dan evaluasi.Hasil dan Pembahasan - Setelah dilakukan asuhan keperawatan masalah - kelebihan volume cairan belum teratasi, Oleh karena itu, perlu dilanjutkan intervensi dengan pemantauan intake dan output cairan yang ketat, perhitungan balance cairan, timbang berat badan secara berkala, edukasi pembatasan cairan, pemberian terapi farmakologi dan hemodialisa.Saran - Pada pengelolaan kebutuhan cairan pada pasien gagal ginjal kronik perlu dilakukan rencana pemantauan intake dan output cairan yang ketat supaya peningkatan berat badan dan edema bisa dikendalikan

The effect of Spirulina supplementation on lipid profile: GRADE-assessed systematic review and dose-response meta-analysis of data from randomized controlled trials

Background: Cardiovascular diseases (CVD) are one of the most important causes of death worldwide. Dyslipidemia is one of the main causal risk factors for CVD that can be controlled by modifying lifestyle, which entails the use of healthy diets containing functional foods. The present study was conducted to summarize the effects of Spirulina on the lipid profile in previous randomized controlled trials. Methods: MEDLINE, Scopus, Clarivate Analytics Web of Science, and the Cochrane Library databases were searched systematically until January 2023, for clinical interventions that investigated the effect of Spirulina supplementation on plasma lipid profile concentrations. Results: ooled results of 20 studies (with 23 arms and 1076 participants) indicated that Spirulina intervention significantly reduced LDL-C (SMD: −0.6, 95% CI: −0.9, −0.2, P<0.05), TC (SMD: −0.6, 95% CI: −0.9, −0.2, P<0.05) and TG (SMD: −0.6, 95% CI: −0.9, −0.2, P<0.05) levels while HDL-C levels were significantly increased (SMD: 0.3, 95% CI: 0.0, 0.6, P<0.05). Conclusions: The findings of the present meta-analysis and review show the usefulness of supplementing with Spirulina in improving serum levels of TC, TG, LDL-C, and HDL-C