Stents in pediatric and adult congenital cardiac catheterization in France in 2013

Stents have contributed to the development of the interventional catheterization for congenital heart diseases (CHD). The aim of this study was to describe indications, results and adverse events in current practice.MethodsThe participation to this study was proposed to all catheterization laboratories specialized in CHD in France (M3C network). All cases with stents implantation in 2013 in pediatric and adult CHD were retrospectively included. Adverse events were assessed using the Bergersen classification.Results174 stents were implanted during 132 procedures in 127 patients by 6 main operators in 9 centers. Patients were aged 15.7±15.1years old (min 5day-old - max 70years old). Sixteen types of procedures were identified. Main indications were transcatheter pulmonary valve replacement (29 patients, 23.0%), pulmonary artery branches angioplasty (34 patients, 27.0%), aortic (re)coarctation stenting (37 patients, 29.4%) and ductus arteriosus stenting (11 patients, 8.7%). 18 patients (14.3%) were under one y.o and 35 (27.8%) were over 18y.o. Main pathologies were tetralogy of Fallot and variants (ACC-CHD 8.3, n=45, 35.7%), and aortic coarctation (ACC-CHD 9.2, n=36, 28.6%). More than 1 stent was implanted in 32 procedures (24.4%, max. 5 stents). Main stents implanted were the CP stent (33.0%), EV3 LD max (22.0%), Valeo (16.2%) and valved stents (15.0%). 98.5% procedures were considered as successful. Serious adverse events were observed in 12.9%. After multivariate adjustment, only procedure type was related to the risk of total adverse events (OR: 3.0, 95%CI 1.1–7.9) but not to stent related adverse events. Age, weight, center, operator, type of stents, stent diameter, genetic disorder and type of CHD were not significantly related to the risk of adverse events.ConclusionStents are used in various CHD catheterization procedures, from infancy to adult age. Adverse events rate is significant and seems related to the type of procedure

Le paléolithique inférieur et moyen en Midi toulousain : nouvelles données et perspectives de l’archéologie préventive

Depuis quelques années, les opérations d’archéologie préventive menées en Midi toulousain ont permis de réactualiser certaines données relatives à la géomorphologie des sites paléolithiques inférieur et moyen. Ainsi, plusieurs contextes peuvent être considérés comme plus favorables que d’autres pour la conservation du matériel. Par ailleurs, les résultats préliminaires d’études typo-technologiques des industries mises au jour récemment, offrent de nouvelles perspectives de recherche pour la constitution d’un cadre chrono-culturel plus précis.In the last years, preventive archeology projects conducted in the Midi toulousain Region (southern France) allowed to update data concerning the geomorphology of Early and Middle Palaeolithic sites. It became apparent that certain contexts can be considered as more favorable to vestige conservation than others. Besides, preliminary results of typo-technological studies of recently discovered artifacts offer new research perspectives for the definition of a more precise chrono-cultural frame

Le paléolithique inférieur et moyen en Midi toulousain : nouvelles données et perspectives de l’archéologie préventive

Depuis quelques années, les opérations d’archéologie préventive menées en Midi toulousain ont permis de réactualiser certaines données relatives à la géomorphologie des sites paléolithiques inférieur et moyen. Ainsi, plusieurs contextes peuvent être considérés comme plus favorables que d’autres pour la conservation du matériel. Par ailleurs, les résultats préliminaires d’études typo-technologiques des industries mises au jour récemment, offrent de nouvelles perspectives de recherche pour la constitution d’un cadre chrono-culturel plus précis.In the last years, preventive archeology projects conducted in the Midi toulousain Region (southern France) allowed to update data concerning the geomorphology of Early and Middle Palaeolithic sites. It became apparent that certain contexts can be considered as more favorable to vestige conservation than others. Besides, preliminary results of typo-technological studies of recently discovered artifacts offer new research perspectives for the definition of a more precise chrono-cultural frame

Checking and bootstrapping lexical norms by means of word similarity indexes

In psychology, lexical norms related to the se- mantic properties of words, such as concreteness and va- lence, are important research resources. Collecting such norms by asking judges to rate the words is very time consuming, which strongly limits the number of words that compose them. In the present article, we present a technique for estimating lexical norms based on the latent semantic analysis of a corpus. The analyses conducted emphasize the technique’s effectiveness for several semantic dimensions. In addition to the extension of norms, this technique can be used to check human ratings to identify words for which the rating is very different from the corpus-based estimate

Imaging of cardiovascular risk in patients with Turner's syndrome

Turner's syndrome is a disorder defined by an absent or structurally abnormal second X chromosome and affects around 1 in 2000 newborn females. The standardised mortality ratio in Turner's syndrome is around three-times higher than in the general female population, mainly as a result of cardiovascular disorders. Most striking is the early age at which Turner's syndrome patients develop the life-threatening complications of cardiovascular disorders compared to the general population. The cardiovascular risk stratification in Turner's syndrome is challenging and imaging is not systematically used. The aim of this article is to review cardiovascular risks in this group of patients and discuss a systematic imaging approach for early identification of cardiovascular disorders in these patients