Detection of Opposite Magnetic Polarity in a Light Bridge: Its Emergence and Cancellation in association with LB Fan-shaped Jets

Light bridges (LBs) are relatively bright structures that divide sunspot umbrae into two or more parts. Chromospheric LBs are known to be associated with various activities including fan-shaped jet-like ejections and brightenings. Although magnetic reconnection is frequently suggested to be responsible for such activities, not many studies present firm evidence to support the scenario. We carry out magnetic field measurements and imaging spectroscopy of a LB where fan-shaped jet-like ejections occur with co-spatial brightenings at their footpoints. We study LB fine structure and magnetic field changes using TiO images, Near-InfraRed Imaging Spectropolarimeter, and Halpha data taken by the 1.6~m Goode Solar Telescope. We detect magnetic flux emergence in the LB that is of opposite polarity to that of the sunspot. The new magnetic flux cancels with the pre-existing flux at a rate of 5.6x10^18 Mx/hr. Both the recurrent jet-like ejections and their base brightenings are initiated at the vicinity of the magnetic flux cancellation, and show apparent horizontal extension along the LB at a projected speed of up to 18.4km/s to form a fan-shaped appearance. Based on these observations, we suggest that the fan-shaped ejections may have resulted from slipping reconnection between the new flux emerging in the LB and the ambient sunspot field.Comment: 24pages, 11figures, accepted by the Ap

Multi-dimensional histone methylations for coordinated regulation of gene expression under hypoxia

Hypoxia increases both active and repressive histone methylation levels via decreased activity of histone demethylases. However, how such increases coordinately regulate induction or repression of hypoxia-responsive genes is largely unknown. Here, we profiled active and repressive histone tri-methylations (H3K4me3, H3K9me3, and H3K27me3) and analyzed gene expression profiles in human adipocyte-derived stem cells under hypoxia. We identified differentially expressed genes (DEGs) and differentially methylated genes (DMGs) by hypoxia and clustered the DEGs and DMGs into four major groups. We found that each group of DEGs was predominantly associated with alterations in only one type among the three histone tri-methylations. Moreover, the four groups of DEGs were associated with different TFs and localization patterns of their predominant types of H3K4me3, H3K9me3 and H3K27me3. Our results suggest that the association of altered gene expression with prominent single-type histone tri-methylations characterized by different localization patterns and with different sets of TFs contributes to regulation of particular sets of genes, which can serve as a model for coordinated epigenetic regulation of gene expression under hypoxia.111Ysciescopu

Does acellular dermal matrix expand in response to tissue expander inflation?

Background Acellular dermal matrices (ADMs) have recently become widely used in breast reconstruction, but the correlation between the final expander volume and the surface area of the ADM is not well understood. In this study, the expansion of the surface area of ADM and the expander volume was studied retrospectively in cases of acellular dermis–assisted tissue expander breast reconstruction. Methods Twenty cases of immediate breast reconstruction using an ADM–assisted tissue expander from January 2015 to December 2015 were evaluated. In all 20 cases, CGCryoDerm was used as the matrix, with a thickness of 1–3 mm. No slit incisions were made. Finally, the proportional increase in the area of the fully expanded ADM was compared to that of the tissue expander volume. Results The proportional increase in the ADM surface area was calculated to be from 1.1 to 2.46, with a mean value of 1.7. Additionally, under the assumption that the expander had a spherical shape, the increase in its radius (the cube root of its volume) was assessed. The range of the proportional increase in the expander radius was 1.1 to 2.24, with a mean value of 1.66. The proportional increase in the radius of the expanded ADM surface area ranged from 1.04 to 1.34, with a mean ratio of 1.28. Conclusions The results of this study confirmed that the ADM expanded when the tissue expander was inflated. However, the ADM expanded to a lesser extent than the tissue expander, indicating that the muscle and other tissues expanded more than the ADM when the tissue expander was inflated