A high resolution, adjustable, lockable laser mirror mount

A prototype high resolution, adjustable, lockable mirror mount is described, suitable for use as a resonator end mirror mount in fieldable lasers. The prototype was vibrated to 15g levels, 10-2000 Hz, and was shown to be stable to within 1 arc second and settable to an accuracy of 10 arc seconds. Improvements to be made to the prototype are outlined which will significantly improve the accuracy without sacrificing the other attributes of the prototype

The body as image: image as body

Pain consultations are often contested spaces where patient and clinician compete for the roles of speaker. Often patients are searching for mechanical explanations and clinicians for psychological ones - creating an impasse and causing distress to both parties. Meanwhile, as technology advances and we have increasing means of seeing inside a person’s body we seem to have less and less ability to see inside another’s world – to understand what it means to live with pain, the significance of that pain for that individual in their social context. In this paper we explore the potential for images of pain, co-created with patients, to intervene in this unproductive patient dynamic and bring the full experience of pain - social, emotional, physical - into focus. Narrative analysis is used on a series of transcripts of pain consultations

Vitamin B12 measurements across neurodegenerative disorders.

Background:Vitamin B12 deficiency causes a number of neurological features including cognitive and psychiatric disturbances, gait instability, neuropathy, and autonomic dysfunction. Clinical recognition of B12 deficiency in neurodegenerative disorders is more challenging because it causes defects that overlap with expected disease progression. We sought to determine whether B12 levels at the time of diagnosis in patients with Parkinson's disease (PD) differed from those in patients with other neurodegenerative disorders. Methods:We performed a cross-sectional analysis of B12 levels obtained around the time of diagnosis in patients with PD, Multiple System Atrophy (MSA), Dementia with Lewy Bodies (DLB), Alzheimer's disease (AD), Progressive Supranuclear Palsy (PSP), Frontotemporal Dementia (FTD), or Mild Cognitive Impairment (MCI). We also evaluated the rate of B12 decline in PD, AD, and MCI. Results:In multivariable analysis adjusted for age, sex, and B12 supplementation, we found that B12 levels were significantly lower at time of diagnosis in patients with PD than in patients with PSP, FTD, and DLB. In PD, AD, and MCI, the rate of B12 decline ranged from - 17 to - 47 pg/ml/year, much greater than that reported for the elderly population. Conclusions:Further studies are needed to determine whether comorbid B12 deficiency affects progression of these disorders

Experimental verification of an Oseen flow slender body theory

Consider uniform flow past four slender bodies with elliptical cross-section of constant ellipticity along the length of 0, 0.125, 0.25 and 0.375, respectively, for each body. Here, ellipticity is defined as the ratio of the semiminor axis of the ellipse to the semimajor axis. The bodies have a pointed nose which gradually increases in cross-section with a radius of curvature 419mm to a mid-section which then remains constant up to a blunt end section with semimajor axis diameter 160 mm, the total length of all bodies being 800 mm. The bodies are side-mounted within a low-speed wind tunnel with an operational wind speed of the order 30ms−1. The side force (or lift) is measured within an angle of attack range of −3◦ to 3◦ such that the body is rotated about the major axis of the ellipse cross-section. The lift slope is determined for each body, and how it varies with ellipticity. It is found that this variance follows a straight line which steadily increases with increasing ellipticity. It is shown that this result is predicted by a recently developed Oseen flow slender body theory, and cannot be predicted by either inviscid flow slender body theory or viscous crossflow theories based upon the Allen and Perkins method

A "Starless" Core that Isn't: Detection of a Source in the L1014 Dense Core with the Spitzer Space Telescope

We present observations of L1014, a dense core in the Cygnus region previously thought to be starless, but data from the Spitzer Space Telescope show the presence of an embedded source. We propose a model for this source that includes a cold core, heated by the interstellar radiation field, and a low-luminosity internal source. The low luminosity of the internal source suggests a substellar object. If L1014 is representative, other "starless" cores may turn out to harbor central sources