The natural/neglected relationship: liberalism, identity and India-Australia relations

Published online: 27 Oct 2015Recent commentary on India–Australia relations has defined the relationship as ‘natural’ and based on ‘shared values’ and ‘shared history’. The relationship has simultaneously been considered ‘neglected’. The paradoxical juxtaposition of a natural/neglected partnership is yet to be adequately explained. We consider the historical construction of liberalism in both states as a facet of state identity to argue that, far from creating a natural relationship, differing liberal identities have served to keep these two states apart. This is illustrated through case studies of divergent opinions over the Nuclear Non-Proliferation Treaty, Russia's 2014 annexation of Crimea and the rise of China.Priya Chacko & Alexander E. Davi

Evolution to a chronic disease niche correlates with increased sensitivity to Tryptophan availability for the obligate intracellular bacterium Chlamydia pneumoniae

The chlamydiae are obligate intracellular parasites that have evolved specific interactions with their various hosts and host cell types to ensure their successful survival and consequential pathogenesis. The species Chlamydia pneumoniae is ubiquitous, with serological studies showing that most humans are infected at some stage in their lifetime. While most human infections are asymptomatic, C. pneumoniae can cause more-severe respiratory disease and pneumonia and has been linked to chronic diseases such as asthma, atherosclerosis, and even Alzheimer's disease. The widely dispersed animal-adapted C. pneumoniae strains cause an equally wide range of diseases in their hosts. It is emerging that the ability of C. pneumoniae to survive inside its target cells, including evasion of the host's immune attack mechanisms, is linked to the acquisition of key metabolites. Tryptophan and arginine are key checkpoint compounds in this host-parasite battle. Interestingly, the animal strains of C. pneumoniae have a slightly larger genome, enabling them to cope better with metabolite restrictions. It therefore appears that as the evolutionarily more ancient animal strains have evolved to infect humans, they have selectively become more "susceptible" to the levels of key metabolites, such as tryptophan. While this might initially appear to be a weakness, it allows these human C. pneumoniae strains to exquisitely sense host immune attack and respond by rapidly reverting to a persistent phase. During persistence, they reduce their metabolic levels, halting progression of their developmental cycle, waiting until the hostile external conditions have passed before they reemerge. © 2014, American Society for Microbiology

Implications on SUSY breaking mediation mechanisms from observing Bs→μ+μ−B_s \to \mu^+ \mu^- and the muon (g−2)(g-2)

We consider $B_s \to \mu^+ \mu^-$ and the muon $(g-2)_\mu$ in various SUSY breaking mediation mechanisms. If the decay $B_s \to \mu^+ \mu^-$ is observed at Tevatron Run II with a branching ratio larger than $\sim 2 \times 10^{-8}$, the noscale supergravity (including the gaugino mediation), the gauge mediation scenario with small number of messenger fields and low messenger scale, and a class of anomaly mediation scenarios will be excluded, even if they can accommodate a large muon $(g-2)_\mu$. On the other hand, the minimal supergravity scenario and similar mechanisms derived from string models can accommodate this observation.Comment: 4 pages, 3 figure

Intravenous Immunoglobulin in the Treatment of Vancomycin-Induced Toxic Epidermal Necrolysis

Toxic epidermal necrolysis (TEN), an uncommon but potentially life-threatening skin reaction, is frequently induced by drugs. The mucocutaneous reaction is characterised by bullous detachment of the epidermis and mucous membranes. We present a 9-month-old male with methylmalonic acidaemia, generalised hypotonia, and global developmental delay. He presented with a 3-day history of fever, cough, shortness of breath, and vomiting. Eruption appeared after 5 days of vancomycin treatment. The eruption involved almost 60% of the total body surface area and both eyes. He was successfully treated with intravenous immunoglobulin (IVIG), antibiotics,and appropriate wound management and made a full recovery with negligible sequelae despite the severity of his disease. Important components of successful treatment include early recognition, intensive care, prompt withdrawal of the causative agent, early administration of IVIG, appropriate fluid resuscitation, and control of infection. IVIG might be beneficial in the treatment of TEN; however, controlled studies are needed to evaluate IVIG compared to other modalities

Why do gallium clusters have a higher melting point than the bulk?

Density functional molecular dynamical simulations have been performed on Ga$_{17}$ and Ga$_{13}$ clusters to understand the recently observed higher-than-bulk melting temperatures in small gallium clusters [Breaux {\em et al.}, Phys. Rev. Lett. {\bf 91}, 215508 (2003)]. The specific-heat curve, calculated with the multiple-histogram technique, shows the melting temperature to be well above the bulk melting point of 303 K, viz. around 650 K and 1400 K for Ga$_{17}$ and Ga$_{13}$, respectively. The higher-than-bulk melting temperatures are attributed mainly to the covalent bonding in these clusters, in contrast with the covalent-metallic bonding in the bulk.Comment: 4 pages, including 6 figures. accepted for publication in Phys. Rev. Let

Three-body decays of sleptons in models with non-universal Higgs masses

We compute the three-body decays of charged sleptons and sneutrinos into other sleptons. These decays are of particular interest in SUSY-breaking models with non-universal Higgs mass parameters, where the left-chiral sleptons can be lighter than the right-chiral ones, and lighter than the lightest neutralino. We present the formulas for the three-body decay widths together with a numerical analysis in the context of gaugino-mediated SUSY breaking with a gravitino LSP.Comment: Version published in JHEP. See http://cern.ch/kraml/papers/ for high-res figure

The sparticle spectrum in Minimal gaugino-Gauge Mediation

We compute the sparticle mass spectrum in the minimal four-dimensional construction that interpolates between gaugino mediation and ordinary gauge mediation.Comment: 21 pages, 9 figures; V2: refs. added; V3: some typos correcte

Minimal Gaugino Mediation

We propose Minimal Gaugino Mediation as the simplest known solution to the supersymmetric flavor and CP problems. The framework predicts a very minimal structure for the soft parameters at ultra-high energies: gaugino masses are unified and non-vanishing whereas all other soft supersymmetry breaking parameters vanish. We show that this boundary condition naturally arises from a small extra dimension and present a complete model which includes a new extra-dimensional solution to the mu problem. We briefly discuss the predicted superpartner spectrum as a function of the two parameters of the model. The commonly ignored renormalization group evolution above the GUT scale is crucial to the viability of Minimal Gaugino Mediation but does not introduce new model dependence.Comment: LaTeX, 16 pages, 4 figures, running of the bottom and tau Yukawas included, plots revise