Homoclinic Signatures of Dynamical Localization

It is demonstrated that the oscillations in the width of the momentum distribution of atoms moving in a phase-modulated standing light field, as a function of the modulation amplitude, are correlated with the variation of the chaotic layer width in energy of an underlying effective pendulum. The maximum effect of dynamical localization and the nearly perfect delocalization are associated with the maxima and minima, respectively, of the chaotic layer width. It is also demonstrated that kinetic energy is conserved as an almost adiabatic invariant at the minima of the chaotic layer width, and that the system is accurately described by delta-kicked rotors at the zeros of the Bessel functions J_0 and J_1. Numerical calculations of kinetic energy and Lyapunov exponents confirm all the theoretical predictions.Comment: 7 pages, 4 figures, enlarged versio

Expected exponential loss for gaze-based video and volume ground truth annotation

Many recent machine learning approaches used in medical imaging are highly reliant on large amounts of image and ground truth data. In the context of object segmentation, pixel-wise annotations are extremely expensive to collect, especially in video and 3D volumes. To reduce this annotation burden, we propose a novel framework to allow annotators to simply observe the object to segment and record where they have looked at with a \$200 eye gaze tracker. Our method then estimates pixel-wise probabilities for the presence of the object throughout the sequence from which we train a classifier in semi-supervised setting using a novel Expected Exponential loss function. We show that our framework provides superior performances on a wide range of medical image settings compared to existing strategies and that our method can be combined with current crowd-sourcing paradigms as well.Comment: 9 pages, 5 figues, MICCAI 2017 - LABELS Worksho

The alternative of EXERGAMEs in improving the quality of life of the elderly

Actualmente vivimos en una sociedad claramente condicionada por el alcance de las nuevas tecnologías. Asimismo, el significativo aumento del número de nuestros mayores constituye otra característica que la determina. Esta situación plantea la necesidad de propuestas que promuevan la calidad de vida y bienestar en la tercera edad. Para ello, se ha realizado una revisión bibliográfica considerando el ámbito de la actividad física, el cual se concretada como una de las bazas más importantes a tratar para lograr ese objetivo; y el papel que pueden jugar las nuevas tecnologías en él, concretamente los «Exergames». Por ello, y con el fin de buscar alternativas para la mejora de la salud en la tercera edad, este estudio pretende poner en relieve la utilización de las nuevas tecnologías con dicha meta. En este sentido, se destaca el uso de los videojuegos activos, una tecnología que lleva en auge desde hace algún tiempo, con la cual nuestros mayores podrán no solo mejorar su condición física y mental, sino su calidad de vida de forma global

General exact theory of autoresonance in nonautonomous systems

A general exact theory of autoresonance (self-sustained resonance) in both dissipative and Hamiltonian nonautonomous systems is presented. The equations that together govern the autoresonance solutions and excitations are derived with the aid of a variational principle concerning the power functional. The theory is applied to Duffing oscillators to obtain exact analytical expressions for autoresonance excitations and solutions which explain all the phenomenological and approximate results arising from the previous approach to autoresonance phenomena.Comment: 12 pages, LaTeX; figures adde

Fricke and polymer gel 2D dosimetry validation using Monte Carlo simulation

Complexity in modern radiotherapy treatments demands advanced dosimetry systems for quality control. These systems must have several characteristics, such as high spatial resolution, tissue equivalence, three-dimensional resolution, and dose-integrating capabilities. In this scenario, gel dosimetry has proved to be a very promising option for quality assurance. In this study, the feasibility of Fricke and polymer gel dosimeters suitably shaped in form of thin layers and optically analyzed by visible light transmission imaging has been investigated for quality assurance in external radiotherapy. Dosimeter irradiation was carried out with a 6-MV photon beam (CLINAC 600C). The analysis of the irradiated dosimeters was done using two-dimensional optical transmission images. These dosimeters were compared with a treatment plan system using Monte Carlo simulations as a reference by means of a gamma test with parameters of 1 mm and 2%. Results show very good agreement between the different dosimetric systems: in the worst-case scenario, 98% of the analyzed points meet the test quality requirements. Therefore, gel dosimetry may be considered as a potential tool for the validation of other dosimetric systems.Fil: Vedelago, José Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina. Universidad Nacional de Córdoba; ArgentinaFil: Chacón Obando, D.. Universidad Nacional. Physics Department; Costa Rica. Universidad Nacional de Córdoba; ArgentinaFil: Malano, Francisco Mauricio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina. Universidad Nacional de Córdoba; ArgentinaFil: Conejeros, R.. Servicio de Radioterapia, Icos. Temuco, Chile;Fil: Figueroa, R.. Universidad de la Frontera; ChileFil: Garcia, D.. Servicio de Imagenes por Resonancia Magnética; ChileFil: González, G.. Servicio de Imagenes por Resonancia Magnética; ChileFil: Romero, Marcelo Ricardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; Argentina. Universidad Nacional de Córdoba; ArgentinaFil: Santibañez, M.. Servicio de Imagenes por Resonancia Magnética; ChileFil: Strumia, Miriam Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; ArgentinaFil: Velásquez, J.. Servicio de Radioterapia; ChileFil: Mattea, Facundo. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Departamento de Química Orgánica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Valente, M.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Física Enrique Gaviola. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina. Universidad de La Frontera. Departamento de Ciencias Físicas; Chil

Prevention of Chronic Experimental Colitis Induced by Dextran Sulphate Sodium (DSS) in Mice Treated with FR91

One of the main treatments currently used in humans to fight cancer is chemotherapy. A huge number of compounds with antitumor activity are present in nature, and many of their derivatives are produced by microorganisms. However, the search for new drugs still represents a main objective for cancer therapy, due to drug toxicity and resistance to multiple chemotherapeutic drugs. In animal models, a short-time oral administration of dextran sulfate sodium (DSS) induces colitis, which exhibits several clinical and histological features similar to ulcerative colitis (UC). However, the pathogenic factors responsible for DSS-induced colitis and the subsequent colon cancer also remain unclear. We investigated the effect of FR91, a standardized lysate of microbial cells belonging to the Bacillus genus which has been previously shown to have significant immunomodulatory effects, against intestinal inflammation. Colitis was induced in mice during 5 weeks by oral administration 2% (DSS). Morphological changes in the colonic mucosa were evaluated by hematoxylin-eosin staining and immunohistochemistry methods. Adenocarcinoma and cryptal cells of the dysplastic epithelium showed cathenin-β, MLH1, APC, and p53 expression, together with increased production of IFN-γ. In our model, the optimal dose response was the 20% FR91 concentration, where no histological alterations or mild DSS-induced lesions were observed. These results indicate that FR91 may act as a chemopreventive agent against inflammation in mice DSS-induced colitis

Transfer Hydrogenation of Azo Compounds with Ammonia Borane Using a Simple Acyclic Phosphite Precatalyst

Tris(quinolin-8-yl)phosphite, P(Oquin)(3), promotes the dehydrogenation of H3N center dot BH3 (AB) and the transfer hydrogenation of azoarenes using ammonia borane (AB) as H-2 source. The metal-free reduction of azoarenes proceeds under mild reaction conditions upon which several diphenylhydrazine derivatives are obtained in high yields. The reactivity of P(Oquin)(3) toward AB was evaluated through NMR in situ tests. The rate of the reaction, activation parameters, deuterium kinetic isotope effect (DKIE) and linear-free energy relationship were investigated. Such mechanistic and kinetic studies suggest that P(Oquin)(3) is a precatalyst and that AB is likely involved in more than one stage of the reaction pathway. Furthermore, the kinetic data indicate that the reaction proceeds through an ordered transition state, possibly associative

Optimal driving waveform for overdamped, adiabatic rocking ratchets

As a first step in the project of ratchet optimisation, the optimal driving waveform among a wide class of admissible functions for an overdamped, adiabatic rocking ratchet is shown to be dichotomous. `Optimum' is defined as that which achieves the maximum (or minimum negative) average particle velocity. Implications for the design of ratchets, for example in nanotechnological transport, may follow. The main result is applicable to a general class of adiabatic responses.Comment: Submitted to Journal of Physics