125 research outputs found
(1R,4′S)-4-(tert-ButylÂdimethylÂsilanÂoxy)-1-[2,2-dimethyl-3-(p-tolylÂsulfonÂyl)-1,3-oxazolidin-4-yl]but-2-yn-1-ol
The chiral title compound, C22H35NO5SSi, is a precursor of novel furanÂomycin derivatives. It crystallizes with two molecules in the asymmetric unit; these show different conformations of the silyl substitutent, as indicated by the Si—O—C—C torsion angles of 41.4 (7) and −84.5 (5)° in the two molÂecules. The anti configuration of the adjacent stereogenic centers is consistent with the Felkin–Anh model. Each of the two crystallographically independent molÂecules is connected with a neighbouring molÂecule of the same type via two symmetry-equivalent O—H⋯O hydrogen bonds
Solvent- and structure-dependent regioselectivity in the boron-mediated aldol reaction of 2-(1,3-dioxolan-2-yl)ethyl ethyl ketones
Observations on the Influence of Precursor Conformations on Macrocyclization Reactions
Terpenoids Derived from Linalyl Oxide. Part 3. The isolation, structure, absolute configuration and synthesis of the davanafurans, nor-sesquiterpenes isolated fromArtemisia Pallens
Lewis acid- and cationic lithium-mediated diastereoselective aldol-type reaction based on a double chiral recognition manner for the asymmetric synthesis of α-substituted serines
Synthesis of a Highly Functionalized Triquinane: Studies Towards a Total Synthesis of Subergorgic Acid and Its Analogues
Additional Evidence for the Existence of Only One Kind of Transition State in the NABH4 Reduction of Aliphatic Ketones
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