Contenido de carbono y nitrógeno de la biomasa microbiana en suelos de La Habana.

La presente investigacion fue diseñada con el objetivo de calcular el carbono (C) y el nitrogeno(N) inmovilizado en la biomasa microbiana de cuatro suelos Ferraliticos Rojos de la Provincia de La Habana, Cuba,empleando la metodologia de gfumigacion extracción en el año 2006. Se colectaron muestras de cuatro sitios (Bainoa, LaSalud, Quivican y Guanajay), los cuales mostraron diferencias en las caracteristicas fisico-quimicas, incluyendo diferencias en contenido de materia organica entre 2,8 y 5%. La sensibilidad de las metodologías empleadas fue valorada utilizandoel error estandar de las medias como parametro estadístico. Los niveles de C inmovilizados en la biomasa microbianaen los suelos estudiados, variaron entre 289 y 425 ƒÊg/g de suelo y tuvieron una correlacion altamente significativa con el contenido de materia organica del suelo. Los contenidosde N inmovilizados variaron entre 62 y 90 ƒÊg/g de suelo yse observo tambien una correlacion signifi cativa entre esteparametro y el contenido de nitrogeno total. El error estandarde la media para las determinaciones del C microbiano vario entre 2 y 16 y fueron ligeramente superiores a lo hallado en reportes anteriores; mientras que los errores observados en las determinaciones del N microbiano se mantuvieron entre losrangos considerados adecuados. Finalmente la metodologia fue adaptada a las condiciones del laboratorio

Vera Cartonera, entre Gilda y Derrida

El capítulo recupera la historia y el recorrido de Vera Cartonera, una editorial universitaria cartonera que se inscribe en la Universidad Nacional del Litoral y el Instituto de Humanidades y Ciencias del Litoral, dependiente de Conicet.Fil: Pérez Aguilar, Anahí Lucía. No especifíca;Fil: Airaldi, Candela. No especifíca;Fil: Ariel, Federico. No especifíca;Fil: Balangero, Julián. No especifíca;Fil: Baldini, Virginia. No especifíca;Fil: Bitar, Francisco Miguel. Universidad Nacional del Litoral. Instituto de Humanidades y Ciencias Sociales del Litoral. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Humanidades y Ciencias Sociales del Litoral; ArgentinaFil: Bonetti, Carola. No especifíca;Fil: Bórtoli, Pamela. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Carrio, Cintia Valeria. Universidad Nacional del Litoral. Instituto de Humanidades y Ciencias Sociales del Litoral. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Humanidades y Ciencias Sociales del Litoral; ArgentinaFil: Coutaz, Federico. No especifíca;Fil: Cumin, Larisa Belén. No especifíca;Fil: Chávez, Félix. No especifíca;Fil: Cherri, Guillermina. No especifíca;Fil: Chialva, Ivana Selene. Universidad Nacional del Litoral. Instituto de Humanidades y Ciencias Sociales del Litoral. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Humanidades y Ciencias Sociales del Litoral; ArgentinaFil: Dolzani, Sofía Macarena. Universidad Nacional del Litoral. Instituto de Humanidades y Ciencias Sociales del Litoral. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Humanidades y Ciencias Sociales del Litoral; ArgentinaFil: Ferrante, Enzo. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Gauna, Daniela Fernanda. Universidad Nacional del Litoral. Instituto de Humanidades y Ciencias Sociales del Litoral. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Humanidades y Ciencias Sociales del Litoral; ArgentinaFil: Gerbaudo, Analía Isabel. Universidad Nacional del Litoral. Instituto de Humanidades y Ciencias Sociales del Litoral. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Humanidades y Ciencias Sociales del Litoral; ArgentinaFil: Gómez Anziani, Guillermina. No especifíca;Fil: Gudiño, Micaela. No especifíca;Fil: Ibáñez, Susana. No especifíca;Fil: Kiener, Laura. No especifíca;Fil: Larker, Vera. No especifíca;Fil: Molinas, Isabel Sabina. No especifíca;Fil: Miglioli, Valentina. No especifíca;Fil: Mihal, Ivana Julieta. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Nudelman, Ianina. No especifíca;Fil: Perticará, Mariana Andrea. No especifíca;Fil: Ramírez, Cristian. No especifíca;Fil: Sabena, María Julia. Universidad Nacional del Litoral; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Sanseverinatt, Zoe. No especifíca;Fil: Santomero, Lucila. Universidad Nacional del Litoral. Instituto de Humanidades y Ciencias Sociales del Litoral. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Humanidades y Ciencias Sociales del Litoral; ArgentinaFil: Sierra, Gabriela. Universidad Nacional del Litoral. Instituto de Humanidades y Ciencias Sociales del Litoral. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Humanidades y Ciencias Sociales del Litoral; ArgentinaFil: Sobré, Amalia. No especifíca;Fil: Sterli, Laura. No especifíca;Fil: Szpilbarg, Daniela. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Torres, Patricia. No especifíca;Fil: Tosti, Ivana. No especifíca;Fil: Venturini, Santiago. Universidad Nacional del Litoral. Instituto de Humanidades y Ciencias Sociales del Litoral. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Santa Fe. Instituto de Humanidades y Ciencias Sociales del Litoral; ArgentinaFil: Yódice, Paula. No especifíca

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

Impact of the International Nosocomial Infection Control Consortium (INICC) Multidimensional Hand Hygiene Approach During 3 Years in 6 Hospitals in 3 Mexican Cities

To evaluate the impact of the International Nosocomial Infection Control Consortium (INICC) multidimensional hand hygiene (HH) approach in Mexico, and analyze predictors of poor HH compliance. From June 2002 to April 2006, we conducted a prospective, observational, before-and-after study in 8 intensive care units (ICUs) from 6 hospitals in 3 cities of Mexico. The approach included administrative support, availability of supplies, education and training, reminders in the workplace, process surveillance, and performance feedback. A total of 13,201 observations for HH opportunities were done in each ICU, during randomly selected 30-minute periods. Overall, HH compliance increased from 45% to 79% (95% confidence interval [CI], 69.1-86.5; P = 0.01). Univariate and multivariate analyses showed that several variables were significantly associated with poor HH compliance: males versus females (61% versus 66%; 95% CI, 0.91-0.96; P = 0.0001), physicians versus nurses (62% versus 67%; 95% CI, 0.91-0.97; P = 0.0001), and adult versus neonatal ICUs (67% versus 54%; 95% CI, 0.79-0.84; P = 0.0001), among others. Hand hygiene programs should focus on variables found to be predictors of poor HH compliance

Parathyroidectomy in chronic kidney disease patients in Argentina: pre surgical studies, types of surgery, recurrence and persistence

Introduction: Parathyroidectomy (PTx) is the selecte treatment for patients with severe secondary hyperparathyroidism, refractory to medical treatment. There is not enough information about this procedure in Argentina, that is the reason why we performed this study. Methods: 255 patients with PTx were included from the year 2003 to 2007 on a voluntary register. Studies of pre-surgical localization, phosphocalcic metabolism laboratories before and after surgery were evaluated, and the type of surgical technique used. The persistence and recurrence of post-surgical hyperparathyroidism was analyzed. Results: The PTx rate was 2,7/1000 patients year. 83% of the patients had neck echography and 59% Sestamibi scans with Tc 99. There was a positive correlation (p<0,001) between the number of detected glands by echography and Sestamibi. The parathyroidectomy performed was: subtotal in 77%, total with self-implant in 14% and total without self-implant in 9%. There were significant falls of Ca and P, Alkaline Phosphatase and PTH (1744±788 pg/ml to 247±450 pg/ml; p<0.0001) post-surgical. 2.4 ±2,5 months after the PTx, 72% of patients had PTH <2 50 pg/ml, 19,8% had persistence and 8,3% had recurrence. According to the type of surgery, the persistence and recurrence were for subtotal PTx 22% and 8,3%, total PTx with implant 11% and 11%, and total PTx without selfimplant 13% and 4% respectively. The performance of the Sestamibi scan did not affect the PTx results. No noticeable differences were observed among the centers for persistence and recurrence. Conclusions: The PTx rate was very low, echography was the preferred method of pre-surgical localization, and subtotal PTx was the most used surgical technique. PTx was successful in most of the patients, and persistence and recurrence were not related to the technique

Compilación de Proyectos de Investigación desde el año 2003 al 2012

Listado de Proyectos de investigación de UPIICSA desde 2003 a 201

Charged-particle multiplicity fluctuations in Pb–Pb collisions at √sNN = 2.76 TeV

Measurements of event-by-event fluctuations of charged-particle multiplicities in Pb–Pb collisions at sNN−−−√ = 2.76 TeV using the ALICE detector at the CERN Large Hadron Collider (LHC) are presented in the pseudorapidity range |η|<0.8 and transverse momentum 0.2<pT<2.0 GeV/c. The amplitude of the fluctuations is expressed in terms of the variance normalized by the mean of the multiplicity distribution. The η and pT dependences of the fluctuations and their evolution with respect to collision centrality are investigated. The multiplicity fluctuations tend to decrease from peripheral to central collisions. The results are compared to those obtained from HIJING and AMPT Monte Carlo event generators as well as to experimental data at lower collision energies. Additionally, the measured multiplicity fluctuations are discussed in the context of the isothermal compressibility of the high-density strongly-interacting system formed in central Pb–Pb collisions