Late Quaternary Activity of the La Rinconada Fault Zone, San Juan, Argentina

Most of the permanent deformation in the Pampean Flat slab segment of the central Andes is taken up at the Andean Orogenic Front in Argentina, a narrow zone between the Eastern Precordillera and Sierras Pampeanas that comprises one of the world's most seismically active thrust zones. Active faults and folds in the region have been extensively mapped but still largely lack information on style and rates of deformation, which is essential for understanding the distribution of regional strain and estimating the seismic potential of individual faults. Structural, geomorphic, and 36Cl cosmogenic radionuclide surface exposure age methods are used to focus on key sites along the 30-km-long La Rinconada Fault Zone in this region of west-central Argentina, which is ~15 km away from the highly populated (~500,000) city of San Juan, to define a late Quaternary average shortening rate of 0.41 ± 0.01 mm/year. This slip rate is the same order of magnitude, but slightly lower than nearby similar east dipping Eastern Precordillera faults including the La Laja and Las Tapias Faults. Relatively low slip rates are interpreted as being a consequence of distributed deformation between the latitude of the La Rinconada Fault Zone (31 and 32°S), as compared to between latitudes 32 to 33°S where deformation appears to be focused on fewer structures, including the Las Peñas and La Cal Thrust Faults. The La Rinconada Fault Zone is capable of generating earthquakes of Mw 6.6–7.2, but further investigations are required to determine timing and recurrence intervals of discrete events.Fil: Rimando, Jeremy. University of Toronto; CanadáFil: Schoenbohm, Lindsay. University of Toronto; CanadáFil: Costa, Carlos Horacio. Universidad Nacional de San Luis. Facultad de Ciencias Físico Matemáticas y Naturales. Departamento de Geología; ArgentinaFil: Owen, Lewis. University of Cincinnati; Estados UnidosFil: Cesta, Jason M.. University of Cincinnati; Estados UnidosFil: Richard, Andrés David. Universidad Nacional de San Luis. Facultad de Ciencias Físico Matemáticas y Naturales. Departamento de Geología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis; ArgentinaFil: Gardini, Carlos Enrique. Universidad Nacional de San Luis. Facultad de Ciencias Físico Matemáticas y Naturales. Departamento de Geología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis; Argentin

Sleep assessment in a population-based study of chronic fatigue syndrome

BACKGROUND: Chronic fatigue syndrome (CFS) is a disabling condition that affects approximately 800,000 adult Americans. The pathophysiology remains unknown and there are no diagnostic markers or characteristic physical signs or laboratory abnormalities. Most CFS patients complain of unrefreshing sleep and many of the postulated etiologies of CFS affect sleep. Conversely, many sleep disorders present similarly to CFS. Few studies characterizing sleep in unselected CFS subjects have been published and none have been performed in cases identified from population-based studies. METHODS: The study included 339 subjects (mean age 45.8 years, 77% female, 94.1% white) identified through telephone screen in a previously described population-based study of CFS in Wichita, Kansas. They completed questionnaires to assess fatigue and wellness and 2 self-administered sleep questionnaires. Scores for five of the six sleep factors (insomnia/hypersomnia, non-restorative sleep, excessive daytime somnolence, sleep apnea, and restlessness) in the Centre for Sleep and Chronobiology's Sleep Assessment Questionnaire(© )(SAQ(©)) were dichotomized based on threshold. The Epworth Sleepiness Scale score was used as a continuous variable. RESULTS: 81.4% of subjects had an abnormality in at least one SAQ(© )sleep factor. Subjects with sleep factor abnormalities had significantly lower wellness scores but statistically unchanged fatigue severity scores compared to those without SAQ(© )abnormality. CFS subjects had significantly increased risk of abnormal scores in the non-restorative (adjusted odds ratio [OR] = 28.1; 95% confidence interval [CI]= 7.4–107.0) and restlessness (OR = 16.0; 95% CI = 4.2–61.6) SAQ(© )factors compared to non-fatigued, but not for factors of sleep apnea or excessive daytime somnolence. This is consistent with studies finding that, while fatigued, CFS subjects are not sleepy. A strong correlation (0.78) of Epworth score was found only for the excessive daytime somnolence factor. CONCLUSIONS: SAQ(© )factors describe sleep abnormalities associated with CFS and provide more information than the Epworth score. Validation of these promising results will require formal polysomnographic sleep studies