87 research outputs found

    Primary gliosarcoma: key clinical and pathologic distinctions from glioblastoma with implications as a unique oncologic entity

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    This report presents the historical experience, clinical presentation, treatment, prognosis, and pathogenesis of gliosarcoma described to date in the English literature. PubMed query of term “gliosarcoma” was performed, followed by a rigorous review of cited literature. Articles selected for analysis included: (1) case reports of gliosarcoma, (2) review articles of gliosarcoma, and (3) studies of the pathogenesis or genetics of gliosarcoma in humans. Our review identified 219 cases of gliosarcoma in 34 reports and eight articles addressing the pathogenesis. Survival in larger series ranged 4–11.5 months. Features unique to gliosarcoma compared to glioblastoma (GBM) include their temporal lobe predilection, potential to appear similar to a meningioma at surgery, repeated reports of extracranial metastases, and infrequency of EGFR mutations. Published experience is limited to small case series, and the pathogenesis remains unclear. Clinical and pathologic characteristics distinct from GBM suggest that they may warrant specific treatment, separate from conventional GBM therapy

    Comparison between a PPG wearable device and an AFE4403-based pulse oximeter

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    The paper shows a comparison between a photoplethysmography wearable device and a bare pulse-oximeter based on an analog front-end for optical bio-sensing applications. In particular, a specific experimental set-up was implemented, simulating an artery, which allows to compare and acquire signals from both proposed devices on a repeatable system. Results both on the artery model and on a healthy volunteer are shown

    Haemangiopericytoma and meningioma presenting clinically with intracranial haemorrhage: report of three cases and review of the literature.

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    We report one case of haemangiopericytoma and two cases of meningioma whose presenting symptom was subarachnoid haemorrhage. We discuss the etiopathogenetic factors involved in this rare mode of onset in the light of the published work

    Hemangiopericytoma and meningioma presenting clinically with intracranial haemorrhage: report of three cases and review of the literature.

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    We report one case of haemangiopericytoma and two cases of meningioma whose presenting symptom was subarachnoid haemorrhage. We discuss the etiopathogenetic factors involved in this rare mode of onset in the light of the published work
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