20 research outputs found

    INTRAEMPREENDEDORISMO NA ADMINISTRAÇÃO PÚBLICA: O CASO DE UM PROFISSIONAL VANGUARDISTA NA EDUCAÇÃO

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    Este estudo de caso teve como ponto de partida o constructo elaborado por Gifford Pinchot III (1989) acerca das características dos intraempreendedores. Por meio de uma abordagem qualitativa este estudo de caso buscou explorar a trajetória de um profissional da área pública, com vistas à identificação de características intraempreendedoras à luz do constructo de Pinchot III (1989). Os dados coletados na entrevista evidenciaram características intraempreendedoras no sujeito analisado. Tal constatação ficou evidente a partir dos relatos obtidos e da descrição das atividades executadas pelo entrevistado; o qual ao longo da carreira ocupou relevantes cargos políticos, tendo sido vereador e secretário de governo no município de São José em Santa Catarina, além de ter atuado como reitor na Universidade do Estado de Santa Catarina no ano de 2002. Os resultados obtidos no estudo, quando confrontados com a teoria base desse artigo, evidenciaram a presença de traços intraempreendedores (Pinchot III, 1989) no profissional analisado

    AS FIGURAS DOS AGENTES DISFARÇADO, PROVOCADOR E INFILTRADO SOB A ÓTICA DO PACOTE ANTE CRIMES E O POSICIONAMENTO DO SUPERIOR TRIBUNAL DE JUSTIÇA PELA ILEGALIDADE DO FLAGRANTE PREPARADO

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    Um problema real na sociedade é o crime organizado que ocupa os espaços abandonados pelo Estado. Neste contexto se fortaleceu o chamado Pacote Ante Crimes, que instituiu a figura do Agente Disfarçado, aquele que exerce suas funções à paisana, com o intuito de facilitar o recolhimento de informações e a captura imediata, em sede de flagrante, de indivíduos que estejam cometendo crime ligados ao porte e posse de arma de fogo e ao tráfico de droga. No entanto esta figura deve manter-se dentro das balizas impostas pelo STF que sumulou: “Não há crime, quando a preparação do flagrante pela polícia torna impossível a sua consumação”, que doutrinariamente pode ser chamado de Flagrante Preparado ou Provocador. O entendimento do STF também se aplica ao Agente Infiltrado, sua legalidade, indispensável é a existência de elementos preexistentes à ação policial e que indiquem a pretérita existência do delito. Disso, infere-se que o agente não irá influenciar à tomada de decisão do criminoso, pois já existe elementos informativos mínimos à constatação da infração penal, agindo, por tanto, de forma livre e consciente para cometer o crime. Nesse pórtico, sedimenta-se o entendimento de que as figuras do agente disfarçado e do agente infiltrado, em nada se assemelham ao agente provocador, pois esse, necessita que o policial instigue o cometimento do crime, faça nascer o desejo de delinquir, o que é ilegal e não admitido pelo ordenamento jurídico brasileiro

    PRODUÇÃO ACADÊMICA SOBRE EXPERIÊNCIAS EM SERVIÇOS: UMA REVISÃO SISTEMÁTICA

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    A presente pesquisa tem por objetivo analisar a produção acadêmica sobre o tema “experiência em serviços”, a partir de levantamento de artigos científicos publicados em periódicos vinculados às bases de dados Web of Science, Scopus, Ebsco e Emerald. Com uso das palavras-chave "Service* Experience", "Consumer experience" and “Service*”, e "Customer experience” and “Service*”, 2.864 artigos foram identificados. Após depurações, 110 foram selecionados para compor a revisão sistemática. Entre os principais resultados, destaca-se o crescimento do volume de publicações a partir de 2012, indicando ser tema de interesse atual. Os trabalhos analisados trazem como principais palavras-chave “customer experience” e “service experience”, termos igualmente em destaque na revisão de literatura. A análise dos procedimentos metodológicos indicou a predominância da abordagem quantitativa, com pesquisa do tipo surveye uso de análise fatorial confirmatória como procedimento estatístico mais recorrente.

    OFICINA DE EXTRAÇÃO DE PIGMENTOS VEGETAIS E PINTURA EM TELA

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    A oficina de extração de pigmentos vegetais foi desenvolvida com asturmas de 7º ano do Colégio UNESC, dentro do conteúdo do Reino das Plantase teve como objetivo desenvolver conceitos científicos sobre as cores e seuspigmentos na disciplina de ciências. A atividade consiste em coletar diversostipos de elementos naturais e macerá-los com álcool a fim de obter o pigmentoque será utilizado na pintura das telas. Com o uso desta oficina, pode-setrabalhar de forma mais clara alguns conceitos científicos de ciências no Reinodas Plantas, além de remeter a história. Com a utilização desta metodologia oprocesso de aprendizagem tornou-se mais prazeroso despertando acuriosidade, uma vez que, durante todo o desenvolvimento, os envolvidosbuscaram responder as suas dúvidas, muitas vezes sem ter a exata noção doprocesso, que permitia, contudo, avançar, pelo aguçamento da curiosidade

    Estudo comparativo entre ultra-sonografia e cistoscopia na detecção da recidiva de câncer de bexiga

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    Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina. Dapartamento de Clínica Cirúrgica

    Benzophenone guttiferone A from Garcinia achachairu Rusby (Clusiaceae) Presents Genotoxic Effects in Different Cells of Mice

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    Benzophenones from natural sources and those of synthetic analogues present several reports of potent biological properties, and Guttiferone A represents a promising medicinal natural compound with analgesic and gastroprotective profiles. Considering that there are no reports that assess the genetic toxicity of Guttiferone A, the present study was undertaken to investigate the genotoxic potential of this benzophenone isolated from seeds of Garcinia achachairu in terms of DNA damage in different cells of Swiss albino mice using the comet assay, and its clastogenic/aneugenic effects in bone marrow cells in vivo by the micronucleus test. Cytotoxicity was assessed by scoring polychromatic (PCE) and normochromatic (NCE) erythrocytes ratio. Guttiferone A was administered by oral gavage at doses of 15, 30 and 60 mg/kg. The results showed that Guttiferone A produced genotoxic effects in leukocytes, liver, bone marrow, brain and testicle cells and clastogenic/aneugenic effects in bone marrow erythrocytes of mice. The PCE/NCE ratio indicated no cytotoxicity. Since guttiferone A is harmful to the genetic material we suggest caution in its use by humans.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES

    Vasodilation and Blood Pressure-Lowering Effect of 3-Demethyl-2-Geranyl-4-Prenylbellidifoline, a Xanthone Obtained from <i>Garcinia achachairu</i>, in Hypertensive Rats

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    3-demethyl-2-geranyl-4-prenylbellidifoline (DGP), a natural xanthone isolated from Garcinia achachairu, has previously demonstrated remarkable diuretic and renal protective actions. The present study expands its actions on the cardiovascular system by evaluating its vasorelaxant and blood pressure-lowering effects in spontaneously hypertensive rats (SHRs). Aortic endothelium-intact (E+) preparations of SHRs pre-contracted by phenylephrine and exposed to cumulative concentrations of G. achachairu extract, fractions, and DGP exhibited a significant relaxation compared to vehicle-only exposed rings. The non-selective muscarinic receptor antagonist (atropine), the non-selective inhibitor of nitric oxide synthase (L-NAME), as well as the inhibitor of soluble guanylate cyclase (ODQ) altogether avoided DGP-induced relaxation. Tetraethylammonium (small conductance Ca2+-activated K+ channel blocker), 4-aminopyridine (a voltage-dependent K+ channel blocker), and barium chloride (an influx-rectifying K+ channel blocker) significantly reduced DGP capacity to induce relaxation without the interference of glibenclamide (an ATP-sensitive inward rectifier 6.1 and 6.2 K+ channel blocker). Additionally, administration of DGP, 1 mg/kg i.v., decreased the mean, systolic, and diastolic arterial pressures, and the heart rate of SHRs. The natural xanthone DGP showed promising potential as an endothelium-dependent vasorelaxant, operating through the nitric oxide pathway and potassium channels, ultimately significantly reducing blood pressure in hypertensive rats

    Association between accessory gene regulator polymorphism and mortality among critically III patients receiving vancomycin for nosocomial MRSA bacteremia : acohort study

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    Background. Polymorphism of the accessory gene regulator group II (agr) in methicillin-resistant Staphylococcus aureus (MRSA) is predictive of vancomycin failure therapy. Nevertheless, the impact of group II agr expression on mortality of patients with severe MRSA infections is notwell established. Objective.The goal of our study was to evaluate the association between agr polymorphism and all-cause in-hospital mortality among critically ill patients receiving vancomycin for nosocomial MRSA bacteremia. Methods. All patients with documented bacteremia by MRSA requiring treatment in the ICU between May 2009 and November 2011 were included in the study. Cox proportional hazards regression was performed to evaluate whether agr polymorphism was associated with all-cause in-hospital mortality. Covariates included age, APACHE II score, initial C-reactive protein plasma levels, initial serum creatinine levels, vancomycin minimum inhibitory concentration, vancomycin serum levels, and time to effective antibiotic administration. Results. The prevalence of group I and group II agr expression was 52.4% and 47.6%, respectively. Bacteremia by MRSA group III or group IV agr was not documented in our patients. The mean APACHE II of the study population was 24.3 (standard deviation 8.5). The overall cohort mortality was 66.6% (14 patients). After multivariate analysis, initial plasma C-reactive protein levels ( = 0.01), initial serum creatinine levels ( = 0.008), and expression of group II agr ( = 0.006) were positively associated with all-cause in-hospital mortality. Patients with bacteremia by MRSA with group II agr expression had their risk of death increased by 12.6 times when compared with those with bacteremia by MRSA with group I agr expression. Conclusion. Group II agr polymorphism is associated with an increase in mortality in critically ill patients with bacteremia by MRSA treated with vancomycin

    Association between accessory gene regulator polymorphism and mortality among critically III patients receiving vancomycin for nosocomial MRSA bacteremia : acohort study

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    Background. Polymorphism of the accessory gene regulator group II (agr) in methicillin-resistant Staphylococcus aureus (MRSA) is predictive of vancomycin failure therapy. Nevertheless, the impact of group II agr expression on mortality of patients with severe MRSA infections is notwell established. Objective.The goal of our study was to evaluate the association between agr polymorphism and all-cause in-hospital mortality among critically ill patients receiving vancomycin for nosocomial MRSA bacteremia. Methods. All patients with documented bacteremia by MRSA requiring treatment in the ICU between May 2009 and November 2011 were included in the study. Cox proportional hazards regression was performed to evaluate whether agr polymorphism was associated with all-cause in-hospital mortality. Covariates included age, APACHE II score, initial C-reactive protein plasma levels, initial serum creatinine levels, vancomycin minimum inhibitory concentration, vancomycin serum levels, and time to effective antibiotic administration. Results. The prevalence of group I and group II agr expression was 52.4% and 47.6%, respectively. Bacteremia by MRSA group III or group IV agr was not documented in our patients. The mean APACHE II of the study population was 24.3 (standard deviation 8.5). The overall cohort mortality was 66.6% (14 patients). After multivariate analysis, initial plasma C-reactive protein levels ( = 0.01), initial serum creatinine levels ( = 0.008), and expression of group II agr ( = 0.006) were positively associated with all-cause in-hospital mortality. Patients with bacteremia by MRSA with group II agr expression had their risk of death increased by 12.6 times when compared with those with bacteremia by MRSA with group I agr expression. Conclusion. Group II agr polymorphism is associated with an increase in mortality in critically ill patients with bacteremia by MRSA treated with vancomycin

    Association between accessory gene regulator polymorphism and mortality among critically III patients receiving vancomycin for nosocomial MRSA bacteremia : acohort study

    Get PDF
    Background. Polymorphism of the accessory gene regulator group II (agr) in methicillin-resistant Staphylococcus aureus (MRSA) is predictive of vancomycin failure therapy. Nevertheless, the impact of group II agr expression on mortality of patients with severe MRSA infections is notwell established. Objective.The goal of our study was to evaluate the association between agr polymorphism and all-cause in-hospital mortality among critically ill patients receiving vancomycin for nosocomial MRSA bacteremia. Methods. All patients with documented bacteremia by MRSA requiring treatment in the ICU between May 2009 and November 2011 were included in the study. Cox proportional hazards regression was performed to evaluate whether agr polymorphism was associated with all-cause in-hospital mortality. Covariates included age, APACHE II score, initial C-reactive protein plasma levels, initial serum creatinine levels, vancomycin minimum inhibitory concentration, vancomycin serum levels, and time to effective antibiotic administration. Results. The prevalence of group I and group II agr expression was 52.4% and 47.6%, respectively. Bacteremia by MRSA group III or group IV agr was not documented in our patients. The mean APACHE II of the study population was 24.3 (standard deviation 8.5). The overall cohort mortality was 66.6% (14 patients). After multivariate analysis, initial plasma C-reactive protein levels ( = 0.01), initial serum creatinine levels ( = 0.008), and expression of group II agr ( = 0.006) were positively associated with all-cause in-hospital mortality. Patients with bacteremia by MRSA with group II agr expression had their risk of death increased by 12.6 times when compared with those with bacteremia by MRSA with group I agr expression. Conclusion. Group II agr polymorphism is associated with an increase in mortality in critically ill patients with bacteremia by MRSA treated with vancomycin
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