Thermal Stability of Type II Modifications Inscribed by Femtosecond Laser in a Fiber Drawn from a 3D Printed Preform

Fiber drawing from a 3D printed perform was recently discussed to go beyond the limitations of conventional optical fiber manufacturing in terms of structure and materials. In this work, the photosensitivity of silica optical fibers to femtosecond laser light, and fabricated by 3D printing a preform, is investigated. The writing kinetics and the thermal performance of Type II modifications are studied by varying the laser pulse energy and investigating the birefringence response of the femtosecond (fs)-laser written structures. Compared with a conventional telecom single mode fiber (SMF28), the fiber made by 3D printing is found to have similar writing kinetics and thermal performance. Additionally, the thermal stability of the imprinted fs-laser induced nanostructures is investigated based on the Rayleigh–Plesset equation, describing a model of nanopores dissolution underpinning Type II modifications with thermal annealing

Sexto reporte de eventos adversos con tratamientos biológicos en Argentina. Informe del registro BIOBADASAR

Objetivo: actualizar los resultados del registro BIOBADASAR sobre seguridad, duración y causas de interrupción del tratamiento luego de 8 años de seguimiento. Métodos: BIOBADASAR es un registro de seguridad de terapias biológicas establecido por la Sociedad Argentina de Reumatología. Se presenta la descripción de BIOBADASAR 3.0, una cohorte compuesta por 53 centros de Argentina seguidos prospectivamente desde agosto de 2010 hasta enero de 2018

Oxyfluoride core silica-based optical fiber with intrinsically low nonlinearities for high energy laser applications

A few-moded silica-based optical fiber fabricated from core materials that possess intrinsically low optical nonlinearities is reported. Specifically, the 8 μm core, 125 μm cladding diameter silicate fiber was composed of a strontium aluminosilicate oxyfluoride core with a fused silica cladding and was fabricated using the molten core method. Relative to conventional optical fibers, reductions of ∼6.3 dB in Brillouin gain coefficient (gB), ∼0.9 dB in Raman gain coefficient (gR), and ∼2.2 dB in thermo-optic coefficient (TOC) were realized as was a “silica-like” nonlinear refractive index (n2) with a value of ∼3x10−20 m2/W. The role of each core material constituent on parameters that drive optical nonlinearities is discussed to provide a materials solution route for low nonlinearity fiber systems. Materially addressing optical nonlinearities represents a simpler and more effective approach to mitigating power-scaling limits in high energy fiber laser systems compared to the geometric approaches employed using microstructured fibers

Treatment of neuromyelitis optica with rituximab: a 2-year prospective multicenter study

International audienc