PCC13 - Potenciais dificuldades no diagnóstico da sífilis secundária

Dentre as doenças sexualmente transmissíveis com manifestação oral, a sífilis destaca-se por sua incidência que tem se tornado cada vez maior na população brasileira com significativo aumento de casos nos últimos anos. O presente trabalho relata o caso de paciente do sexo feminino, 22 anos, leucoderma, fumante e etilista, apresentando lesões multifocais em mucosa oral e pele com 02 mesesde evolução. A paciente relatava ainda perda de peso e tosse

Alpha lipoic acid in burning mouth syndrome - a randomized double-blind placebo-controlled trial

The burning mouth syndrome (BMS) is a chronic condition characterized by oral burning pain in the absence of clinical abnormalities and without established therapy. The purpose of this study was to evaluate the effectiveness of alpha lipoic acid (ALA) in the management of BMS symptoms through a randomized double-blind placebo-controlled trial. Thirty-eight patients (34 women and four men, median age 62.9 years, range 36-78) were included and 31 completed the study. The patients were randomized into two cycles of treatment: one with alpha lipoic acid and one with placebo both administered in identical capsules. These cycles were separated by a washout period of 20 days. The oral symptoms and the treatment response were assessed using a 100-mm visual analog scale before and after each cycle and the global perceived effect score, using a 5-point scale after each treatment cycle. The level of reduction on burning was significant for both treatments (paired t-test: P < 0.05; rp = 0.011; ral < 0.001). Considering the two cycles together, 22 patients reported at least some improvement after ALA use and 23 patients after placebo. Comparison of the oral assessment scores of the two cycles failed to demonstrate the effectiveness of ALA over placebo (t-test: P > 0.05; r = 0.75).FAPESP Sao Paulo State Research Support Foundation`Fundacao de Amparo a Pesquisa do Estado de Sao Paulo - FAPESP`[05/04565-0

Trichosporon inkin: An Uncommon Agent of Scalp White Piedra. Report of Four Cases in Brazilian Children

We report four cases of scalp white piedra (SWP) in Brazilian female children. Morphological and physiological approaches gave inconsistent results for identifying Trichosporon to species level, while the sequencing of the intergenic spacer 1 region of ribosomal DNA accurately identified the agent of SWP as T. inkin. These cases emphasize the occurrence of this species causing this type of infection. the molecular identification of the suspected agent is needed for appropriate epidemiological surveillance of superficial mycoses caused by Trichosporon species.Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Universidade Federal de São Paulo, Dept Microbiol Imunol & Parasitol, Lab Diagnost Micol, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Med, Lab Especial Micol, São Paulo, BrazilUniv São Paulo, Inst Med Trop São Paulo, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Dermatol, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Microbiol Imunol & Parasitol, Lab Diagnost Micol, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Med, Lab Especial Micol, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Dermatol, São Paulo, BrazilWeb of Scienc