Viscosupplementation in the treatment of articular temporomandibular disorders - Systematic review / Viscossuplementação no tratamento das desordens temporomandibulares articulares – Revisão sistemática

Vissupplementation is a minimally invasive and simple technique that replaces synovial fluid with intra-articular injection of hyaluronic acid (HA). This is a kind of treatment suitable for treating temporomandibular joint (TMD) diseases, such as osteoarthritis and disc displacement, with or without reduction.Aim: The purpose of the present study was to evaluate the use of viscossuplementation in the treatment of temporomandibular joint dysfunctions. Material and Methods: The literature, for this, was searched in PubMed and Scielo databases, from 2009 to 2019, using "Viscosuplementation", "Hyaluronic Acid", "Temporomandibular Joint Dysfunctions" and "Osteoarthritis". Exclusion criteria were those that tested on animals and were not related to the subject. Seven selected layouts.Results: From the reading of the studies, it is believed that hyaluronic acid is beneficial in reducing pain levels, improving the patient's quality of life and mandibular function, even being superior to placebo. However, there are still studies that point out the differences in relation to this technique, due to the question of the molecular weight of HA, the number of sessions performed. Conclusion: Therefore, the patients with temporomandibular joint disorders may improve their clinical setting with a viscossupplementation function, however, greater product standardization and new research studies are needed

Neurological changes post-covid-19 infection: signs and symptoms that remain

Since 2019, humanity has faced the pandemic outbreak of COVID-19 disease, caused by the new coronavirus, SARS-CoV-2. Respiratory symptoms of the disease were investigated and monitored worldwide, however, the nervous system lesions induced by COVID-19 did not receive as much attention. The aim of this study was to highlight the neurological alterations after infection of the new coronavirus, thus highlighting the symptoms that remained after Infection by SARS-CoV-2. The review shows relevant data on drugs and SARS-CoV-2, neurological alterations, complications and adverse effects related to COVID-19. At the time of writing this article, in mid-2022, SARS-CoV-2 is still spreading in several countries and infecting the population, leaving many people with temporary or permanent sequelae because of COVID-19

Correlation between parafunctional habits and temporomandibular dysfunction: Systematic review / Correlção entre hábitos parafuncionais e disfunção temporomandibular: Revisão sistemática

Introduction: Temporomandibular dysfunction (TMD) is a term belonging to the orofacial pain group that affects the masticatory muscles, temporomandibular joint and adjacent structures. TMD can be triggered by parafunctional habits, which are actions performed without specific natural function of the human being, becoming risk factors. Objectives: To evaluate through a literature review the correlation between parafunctional habits and temporomandibular dysfunctions. Methods: The articles were researched in the PubMed and Scielo databases, from 2009 to 2019. As inclusion criteria: articles published in English and Portuguese with the key words "Temporomandibular Joint", "Parafunctional Habits" and "Temporomandibular Dysfunction". Themes that were not related to the theme were excluded. Results: Eight articles were selected, in which six of them correlated the parafunctional habits with the signs and symptoms of TMD. Through these studies, it was seen that people develop a painful symptomatology, affecting even quality of life. In parallel, through other articles, there is a possible relationship between the intensity of physical activity with the degree of TMD found, and also the emergence of certain habits after certain surgeries. Conclusion: It is remarkable the correlation between the various parafunctional habits and TMD. Thus, the dentist should be paid, during diagnosis, to their presence and consider, as part of the treatment, guidelines for the reduction of these habits, obtaining success in controlling dysfunction

Uso do laser de baixa potência no tratamento de disfunção temporomandibular muscular - revisão sistemática/ Low-power laser use for tratment of temporomandibular muscle dysfunction: a systematic review

Objetivo: Realizar uma revisão sistemática sobre a eficácia do uso do Laser de Baixa Potência em pacientes com disfunção temporomandibular muscular. Método: Realizou-se uma busca de artigos nas bases de dados PubMed e Scielo, buscando estudos clínicos realizados em humanos, artigos que relatam o uso do Laser de Baixa Potência  em tratamentos e o seu acompanhamento, publicados nos idiomas português e inglês, até o ano de 2019 com os descritores “Low-level”, “Laser Therapy”, “Myofascial Pain” e “Temporomandibular Dysfunction”. Foram excluídos artigos que não apresentavam clareza na metodologia ou não se adequavam à temática pesquisada. Resultados: Após a triagem sete artigos foram selecionados, nos quais os resultados apontaram que laser de baixa potência pode ser utilizado como uma modalidade de tratamento no controle da disfunção temporomandibular dolorosa, possibilitando redução da intensidade de dor à palpação, melhora da percepção subjetiva da dor e da movimentação mandibular, podendo-se observar também efeitos positivos em aspectos psicológicos em pacientes com dor orofacial crônica. Conclusão: De acordo com os estudos antepostos, o uso do Laser de Baixa Potência tem demonstrado em curto prazo, eficácia no auxilio da abertura bucal dos pacientes analisados, permitindo o alivio nas dores dos pacientes, possibilitando melhor qualidade de vida. Contudo, ainda não é um consenso na literatura sobre os melhores parâmetros específicos para gerar efeitos mais satisfatórios. Assim, são necessários mais estudos para desenvolver uma confirmação precisa dos resultados e avaliação de outras doses e protocolos

The Indiscriminate use of Ritalin by Universities in the Health Area at the University of Gurupi – UNIRG

MPH methylphenidate, popularly known as Ritalin, was synthesized in 1954 in Switzerland and marketed in Brazil in 1998, belonging to the class of amphetamines. It acts in the CNS crossing the blood-brain barrier very easily. Used for cognitive improvement by college students. Its excessive consumption leads to dependence and possible side effects. The objective of this study was to analyze 91 university students who answered questionnaires on the theme. The collected data analyzed the incidence of Ritalin use among health academics at the University of Gurupi-UNIRG. After conducting the surveys, it was intended to understand the real reason that leads the student to the indiscriminate use of the drug and its possible consequences, to subsequently conduct guidance regarding the use without a prescription for academic purposes

Diagnóstico diferencial da Síndrome de Takotsubo e infarto agudo do miocárdio: uma revisão sistemática: Differential diagnosis of Takotsubo Syndrome and acute myocardial infarction: a systematic review

A cardiomiopatia de Takotsubo e o infarto agudo do miocárdio compartilham apresentação clínica e risco de morte semelhantes, embora uma das diferenças mais importantes seja a ausência de doença coronariana obstrutiva na cardiomiopatia de Takotsubo. Neste estudo, tem-se como objetivo analisar a literatura disponível avaliando o diagnóstico diferencial entre pacientes com CTT em comparação com pacientes com infarto agudo do miocárdio. Para isso, foi realizada uma revisão sistemática, utilizando-se a Pubmed e a Medline como base de dados. A partir da análise dos estudos e interpretação de suas principais descobertas, concluiu-se que para pacientes com CTT, outras condições e comorbidades, em vez de apenas dislipidemia e/ou outros fatores de risco estabelecidos, sejam responsáveis por um risco de morte comparável ao de IAM. No entanto, as conclusões desse estudo têm várias limitaçõe

Prevalence of bovine fascioliasis, areas at risk and ensuing losses in the state of Goiás, Brazil

Abstract The present study had to determine the prevalence and spatial distribution of areas at risk of bovine fascioliasis in the state of Goiás, central-western Brazil between 2007 and 2014; to evaluate the associations of some epidemiological variables with occurrences of Fasciola hepatica in animals; and to estimate the economic losses that this parasite on the cattle industry. It could be concluded that of 23,255,979 animals slaughtered, the average prevalence of F. hepatica in cattle in Goiás during the period evaluated was 0.0026% (95% CI: 0.0024-0.0028). In the State of Goias, in about then years (since when this parasite was found for the first time by other researchers in 2007), F. hepatica was diagnosed in 168 new municipalities. Using the regression analysis, the effective bovine herd size was a significant risk factor (OR= 1.21; 95% CI 1.1022-1.4510; p ≤ 0.05) for cattle to be infected with fascioliasis in the state of Goiás. The cattle-rearing industry lost approximately R$15,072.75 (US$ 4,785) due to condemn of livers with Fasciola in the state of Goiás. New studies need to be conducted in these regions, with the aim to identify the likelihood of presence of intermediate hosts, which might serve as a source of F. hepatica infection for definitive hosts

Seminário de Dissertação (2024)

Página da disciplina de Seminário de Dissertação (MPPP, UFPE, 2022) Lista de participantes == https://docs.google.com/spreadsheets/d/1mrULe1y04yPxHUBaF50jhaM1OY8QYJ3zva4N4yvm198/edit#gid=

SARS-CoV-2 intra-host diversity, antibody response, and disease severity after reinfection by the variant of concern Gamma in Brazil

Abstract The rapid spread of the SARS-CoV-2 Variant of Concern (VOC) Gamma in Amazonas during early 2021 fueled a second large COVID-19 epidemic wave and raised concern about the potential role of reinfections. Very few cases of reinfection associated with the VOC Gamma have been reported to date, and their potential impact on clinical, immunological, and virological parameters remains largely unexplored. Here we describe 25 cases of SARS-CoV-2 reinfection in Brazil. SARS-CoV-2 genomic analysis confirmed that individuals were primo-infected with distinct viral lineages between March and December 2020 (B.1.1, B.1.1.28, B.1.1.33, B.1.195, and P.2) and reinfected with the VOC Gamma between 3 to 12 months after primo-infection. We found a similar mean cycle threshold (Ct) value and limited intra-host viral diversity in both primo-infection and reinfection samples. Sera of 14 patients tested 10–75 days after reinfection displayed detectable neutralizing antibodies (NAb) titers against SARS-CoV-2 variants that circulated before (B.1.*), during (Gamma), and after (Delta and Omicron) the second epidemic wave in Brazil. All individuals had milder or no symptoms after reinfection, and none required hospitalization. These findings demonstrate that individuals reinfected with the VOC Gamma may display relatively high RNA viral loads at the upper respiratory tract after reinfection, thus contributing to onward viral transmissions. Despite this, our study points to a low overall risk of severe Gamma reinfections, supporting that the abrupt increase in hospital admissions and deaths observed in Amazonas and other Brazilian states during the Gamma wave was mostly driven by primary infections. Our findings also indicate that most individuals analyzed developed a high anti-SARS-CoV-2 NAb response after reinfection that may provide some protection against reinfection or disease by different SARS-CoV-2 variants