Prevalence of sexual dysfunction and its association with lower urinary tract symptoms in men and women over 18 years old : results from the Colombian Overactive Bladder and Lower urinary Tract symptoms (COBaLT) study

Q1Q3Artículo original1576-1578Introduction & Objectives: There is an age-independent association between sexual dysfunction (SD) and LUTS. Few studies have been conducted in Latin America addressing these issues. We aim to determine the prevalence of SD and its association with LUTS in Colombia. Materials & Methods: This is a sub-analysis of a cross-sectional, population-based study conducted in subjects ≥18 years old to evaluate LUTS and overactive bladder (OAB). A sample size of 1,054 subjects was estimated (prevalence of LUTS/OAB 15%, CI 95%, statistical power 80%, precision 3%). We used a multi-stage probabilistic sampling technique to randomly select individuals in the community. SD was defined as ≤21 points in the SHIM and ≤19 in the FSFI-6. For LUTS, we used the 2002 ICS definitions and validated questionnaires. Descriptive and inferential statistics were employed. Results: We included 1,060 participants. Sixty-three (12%) men and 175 (33%) women were sexually inactive. The prevalence of SD was 47% (men 53%, women 39%). The most common SD symptoms were diminished erection maintenance after penetration in men (13%) and poor lubrication in women (43%). Individuals with SD had higher rates of LUTS (Figure 1). Patients with moderate-to-severe LUTS had lower sexual satisfaction rates (men 89% vs 95%, women 72% vs 88%). The multivariate logistic regression model found that diabetes (DM), menopause, urge urinary incontinence (UUI) and nocturia>2 were associated with SD in women. In men, age, depression, high-school education or less and LUTS were associated with SD (Table 1)

Prevalence of metabolic syndrome and its association with lower urinary tract symptoms and sexual function

Objetivos Estimar la frecuencia de síndrome metabólico (SMet) en la consulta urológica ambulatoria y su asociación con los síntomas del tracto urinario inferior y la disfunción eréctil. Material y métodos Estudio retrospectivo que incluyó a todos los hombres de ≥ 40 años que consultaron ambulatoriamente entre 2010 y 2011. Se calculó la prevalencia de SMet, síntomas del tracto urinario inferior y disfunción eréctil. Se utilizó un modelo logístico para comprobar posibles asociaciones, controlando por interacciones y factores de confusión. Resultados Se incluyeron 616 pacientes. Se encontró SMet en el 43,8% (IC 95%: 39,6-48,3) de los pacientes. El análisis bivariado demostró una asociación entre SMet y síntomas del tracto urinario inferior (p < 0,01), pero no con disfunción eréctil. El modelo logístico demostró una asociación independiente entre SMet y la severidad de los síntomas urinarios por puntuación en el IPSS, siendo mayor el riesgo de SMet en aquellos con síntomas moderados que con síntomas leves (OR: 1,83; IC 95%: 1,14-2,94). Se analizaron por separado los diferentes componentes del SMet y se encontraron asociaciones positivas entre diabetes, síntomas severos (OR: 1,3; IC 95%: 1,24-7,1) y disfunción eréctil (OR: 2,57, IC 95%: 1,12-5,8). Conclusión Se confirmó la asociación entre SMet y síntomas del tracto urinario inferior, pero no para disfunción eréctil. La diabetes, un componente específico del SMet sí se asoció con ambas condiciones. Las diferencias geográficas previamente reportadas en la literatura podrían explicar estos resultados. Debido a que el SMet es frecuente entre los pacientes urológicos, un tamizado activo por parte de los urólogos es recomendable.Q4Q3Artículo original522-528Objectives To estimate the frequency of metabolic syndrome (MetS) in a daily urology practice and to determine its association with lower urinary tract symptoms (LUTS) and erectile dysfunction (ED). Material and methods A retrospective study was conducted. Data from all male patients aged ≥ 40 years who attended our outpatient urology clinic from 2010 to 2011 was collected. Prevalence of MetS was determined, and LUTS and ED were assessed. A logistic model was used to determine possible associations, controlling for confounders and interaction factors. Results A total of 616 patients were included. MetS was observed in 43.8% (95% CI 39.6-48.3). The bivariate model showed an association between MetS and LUTS (p < 0.01), but not between MetS and ED. The logistic model showed an association between MetS and the International Prostate Symptom Score (IPSS), while controlling for other variables. Patients exhibiting moderate LUTS had a greater risk for MetS than patients with mild LUTS (OR 1.83, 95% CI 1.14-2.94). After analyzing for individual components of MetS, positive associations were found between diabetes and severe LUTS (OR 1.3, 95% CI 1.24-7.1), and between diabetes and ED (OR 2.57, 95% CI 1.12-5.8). Conclusion This study was able to confirm an association between MetS and LUTS, but not for ED. Specific components such as diabetes were associated to both. Geographical differences previously reported in the literature might account for these findings. Given that MetS is frequent among urological patients, it is advisable that urologists actively screen for it

Supplementary Material for: Impact of Rectal Swabs on Infectious Complications after Transrectal Prostate Biopsy

<p><b><i>Objectives:</i></b> To determine the impact of rectal swabs (RSs) on infectious complications (IC) following prostate biopsy (PB). <b><i>Methods:</i></b> A retrospective cohort study was conducted including all patients subjected to PB between 2009 and 2013. Group B consisted of patients with a RS and group A of patients without. RS reported the presence of gram-positive or negative germs, sensitive or resistant to ciprofloxacin. Antimicrobial prophylaxis was adjusted to the result. Frequency of IC in each group was determined. <b><i>Results:</i></b> Group B had 548 (47.20%) patients and group A 613 (52.80%). From group B, 250 (45.62%) of the RSs showed fluoroquinolone (FQ)-resistant germs. Forty nine (16.44%) patients with sensitive germs vs. 147 (59.51%) with resistant germs had a history of previous FQ treatment (p < 0.0001). IC were observed in 33 (5.49%) patients from group A and in 7 (1.28%) patients from group B (p < 0.0001), requiring hospitalization in 4.99 vs. 1.28%, respectively. IC and hospital admissions were reduced in 76.68 and 74.34%, respectively, following the implementation of RS. <b><i>Conclusions:</i></b> RS and targeted antibiotic prophylaxis prior to PB was associated with a significant reduction in IC and hospital admissions. Ceftriaxone could be an alternative in cases of known resistance. Past history of FQ treatment is associated with increased resistance.</p