28 research outputs found
Measuring and Predicting Individual Differences in Executive Functions at 14Â Months: A Longitudinal Study.
This study of 195 (108 boys) children seen twice during infancy (Time 1: 4.12Â months; Time 2: 14.42Â months) aimed to investigate the associations between and infant predictors of executive function (EF) at 14Â months. Infants showed high levels of compliance with the EF tasks at 14Â months. There was little evidence of cohesion among EF tasks but simple response inhibition was related to performance on two other EF tasks. Infant attention (but not parent-rated temperament) at 4Â months predicted performance on two of the four EF tasks at 14Â months. Results suggest that EF skills build on simpler component skills such as attention and response inhibition.ESR
A sorghum practical haplotype graph facilitates genomeâwide imputation and costâeffective genomic prediction
Successful management and utilization of increasingly large genomic datasets is
essential for breeding programs to accelerate cultivar development. To help with
this, we developed a Sorghum bicolor Practical Haplotype Graph (PHG) pangenome
database that stores haplotypes and variant information. We developed two PHGs
in sorghum that were used to identify genome-wide variants for 24 founders of the
Chibas sorghum breeding program from 0.01x sequence coverage. The PHG called
single nucleotide polymorphisms (SNPs) with 5.9% error at 0.01x coverageâonly
3% higher than PHG error when calling SNPs from 8x coverage sequence. Additionally,
207 progenies from the Chibas genomic selection (GS) training population
were sequenced and processed through the PHG. Missing genotypes were imputed
from PHG parental haplotypes and used for genomic prediction. Mean prediction
accuracies with PHG SNP calls range from .57â.73 and are similar to prediction
accuracies obtained with genotyping-by-sequencing or targeted amplicon sequencing
(rhAmpSeq) markers. This study demonstrates the use of a sorghum PHG to impute SNPs from low-coverage sequence data and shows that the PHG can unify
genotype calls across multiple sequencing platforms. By reducing input sequence
requirements, the PHG can decrease the cost of genotyping, make GS more feasible,
and facilitate larger breeding populations. Our results demonstrate that the PHG is a
useful research and breeding tool that maintains variant information from a diverse
group of taxa, stores sequence data in a condensed but readily accessible format, unifies
genotypes across genotyping platforms, and provides a cost-effective option for
genomic selection
The generation challenge programme platform: semantic standards and workbench for crop science.
doi:10.1155/2008/369601
Recommended from our members
ORIC stripping foil positioner for tandem beam injection
The Oak Ridge Isochronous Cyclotron (ORIC) is used as an energy booster for heavy ions from a 25 MV tandem accelerator. This operation requires precise placement of a stripping foil in the cyclotron for capture of the injected ions into an acceleration orbit. The mechanical design and control of the foil positioning device are described
The generation challenge programme platform: semantic standards and workbench for crop science.
Made available in DSpace on 2018-06-11T17:31:02Z (GMT). No. of bitstreams: 1
SP19709ID31140.pdf: 1225085 bytes, checksum: 6dddb323eb43dbf39f0394e399faba52 (MD5)
Previous issue date: 2009-03-10bitstream/item/178425/1/SP-19709-ID-31140.pdfdoi:10.1155/2008/369601