Study of spacecraft transponder power amplifier Final report

Communications satellite wideband transponder feasibility study with direct RF to RF CONVERSION and TWT in re-entrant mod

Tectonic displacement and far-field isostatic flexure of pluvial lake shorelines, Dixie Valley, Nevada

Abstract Shoreline features formed by the late Pleistocene pluvial Lake Dixie in Dixie Valley, central Nevada, record crustal deformation resulting from isostatic rebound of the Lake Lahontan basin, and from Holocene and historic surface faulting. Constructional beach bars on the east side of Dixie Valley show eastward tilt of 0.16 m/km, indicating that lithospheric flexure due to isostatic rebound is symmetrical with the west side of the Lahontan basin. The tilt signal is potentially complicated by post-Lake Dixie fault displacements on the west side of the valley. However, elevation changes recorded geodetically across the analogous 1983 Borah Peak, Idaho earthquake ruptures suggest that coseismic deformation is probably not significant on the east side of the valley relative to the shoreline elevation uncertainties and the overall tilt signal. A survey of faulted shorelines on the west side of the valley suggest that previous fault slip rates estimated from an earlier survey of these same shorelines are in error by nearly a factor of two. Better constrained slip rates from elsewhere along the fault indicate Holocene vertical slip rates of 0.3-0.5 mm/a, consistent with estimates of long term slip rates on the Dixie Valley fault

Narrow 0\u3csup\u3e+\u3c/sup\u3e state in \u3csup\u3e20\u3c/sup\u3eNe and 0\u3csub\u3e6\u3c/sub\u3e\u3csup\u3e+\u3c/sup\u3e and 0\u3csub\u3e7\u3c/sub\u3e\u3csup\u3e+\u3c/sup\u3e rotational bands

A reanalysis of old data removes the (0+,2+) ambiguity for a very narrow state at Ex(20Ne)=11.55 MeV and gives a unique 0+ assignment. Such a 0+ state corresponds well to a predicted state at 11.494 MeV of unusually small reduced widths for decay to both the ground and first excited state of 16O. This new 0+ state is a better 06+ band head for the 8p-4h states at 15.159 MeV (6+) and 18.538 MeV (8+) than the currently accepted 0+ state at 12.44 MeV. Possible 2+ and 4+ members are considered. The higher 0+ level at Ex=12.44 starts a new 07+ band, and candidates for this band are critically discussed

The Functional and Molecular Effects of Doxycycline Treatment on Borrelia burgdorferi Phenotype

Recent studies have shown that Borrelia burgdorferi can form antibiotic-tolerant persisters in the presence of microbiostatic drugs such as doxycycline. Precisely how this occurs is yet unknown. Our goal was to examine gene transcription by B. burgdorferi following doxycycline treatment in an effort to identify both persister-associated genes and possible targets for antimicrobial intervention. To do so, we performed next-generation RNA sequencing on doxycycline-treated spirochetes and treated spirochetes following regrowth, comparing them to untreated B. burgdorferi. A number of genes were perturbed and most of those which were statistically significant were down-regulated in the treated versus the untreated or treated/re-grown. Genes upregulated in the treated B. burgdorferi included a number of Erp genes and rplU, a 50S ribosomal protein. Among those genes associated with post-treatment regrowth were bba74 (Oms28), bba03, several peptide ABC transporters, ospA, ospB, ospC, dbpA and bba62. Studies are underway to determine if these same genes are perturbed in B. burgdorferi treated with doxycycline in a host environment

Laying the groundwork at the AGS: Recent results from experiment E895

The E895 Collaboration at the Brookhaven AGS has performed a systematic investigation of Au+Au collisions at 2-8 AGeV, using a large-acceptance Time Projection Chamber. In addition to extensive measurements of particle flow, spectra, two-particle interferometry, and strangeness production, we have performed novel hybrid analyses, including azimuthally-sensitive pion HBT, extraction of the six-dimensional pion phasespace density, and a first measurement of the Lambda-proton correlation function.Comment: Presented at Quark Matter 2001, 8 pages, 5 figure

Comparison of Source Images for protons, π−\pi^-'s and Λ\Lambda's in 6 AGeV Au+Au collisions

Source images are extracted from two-particle correlations constructed from strange and non-strange hadrons produced in 6 AGeV Au + Au collisions. Very different source images result from pp vs p$\Lambda$ vs $\pi^-\pi^-$ correlations. These observations suggest important differences in the space-time emission histories for protons, pions and neutral strange baryons produced in the same events

Charged Pion Production in 2 to 8 AGeV Central Au+Au Collisions

Momentum spectra of charged pions over nearly full rapidity coverage from target to beam rapidity have been measured in the 0-5% most central Au+Au collisions in the beam energy range from 2 to 8 AGeV by the E895 Experiment. Using a thermal parameterization to fit the transverse mass spectra, rapidity density distributions are extracted. The observed spectra are compared with predictions from the RQMD v2.3 cascade model and also to a thermal model including longitudinal flow. The total 4$\pi$ yields of the charged pions are used to infer an initial state entropy produced in the collisions.Comment: 13 pgs, 19 figs, accepted by Phys. Rev. C. Data tables available at http://nuclear.ucdavis.edu/~e895/published_spectra.htm

Three-layer model with absorption for conservative estimation of the maximum acoustic transmission coefficient through the human skull for transcranial ultrasound stimulation.

Transcranial ultrasound stimulation (TUS) has been shown to be a safe and effective technique for non-invasive superficial and deep brain stimulation. Safe and efficient translation to humans requires estimating the acoustic attenuation of the human skull. Nevertheless, there are no international guidelines for estimating the impact of the skull bone. A tissue independent, arbitrary derating was developed by the U.S. Food and Drug Administration to take into account tissue absorption (0.3 dB/cm-MHz) for diagnostic ultrasound. However, for the case of transcranial ultrasound imaging, the FDA model does not take into account the insertion loss induced by the skull bone, nor the absorption by brain tissue. Therefore, the estimated absorption is overly conservative which could potentially limit TUS applications if the same guidelines were to be adopted. Here we propose a three-layer model including bone absorption to calculate the maximum pressure transmission through the human skull for frequencies ranging between 100 kHz and 1.5 MHz. The calculated pressure transmission decreases with the frequency and the thickness of the bone, with peaks for each thickness corresponding to a multiple of half the wavelength. The 95th percentile maximum transmission was calculated over the accessible surface of 20 human skulls for 12 typical diameters of the ultrasound beam on the skull surface, and varies between 40% and 78%. To facilitate the safe adjustment of the acoustic pressure for short ultrasound pulses, such as transcranial imaging or transcranial ultrasound stimulation, a table summarizes the maximum pressure transmission for each ultrasound beam diameter and each frequency

Gaps in detailed knowledge of human papillomavirus (HPV) and the HPV vaccine among medical students in Scotland

<p>Background: A vaccination programme targeted against human papillomavirus (HPV) types16 and 18 was introduced in the UK in 2008, with the aim of decreasing incidence of cervical disease. Vaccine roll out to 12–13 year old girls with a catch-up programme for girls aged up to 17 years and 364 days was accompanied by a very comprehensive public health information (PHI) campaign which described the role of HPV in the development of cervical cancer.</p> <p>Methods: A brief questionnaire, designed to assess acquisition of knowledge of HPV infection and its association to cervical cancer, was administered to two different cohorts of male and female 1st year medical students (school leavers: 83% in age range 17–20) at a UK university. The study was timed so that the first survey in 2008 immediately followed a summer's intensive PHI campaign and very shortly after vaccine roll-out (150 students). The second survey was exactly one year later over which time there was a sustained PHI campaign (213 students).</p> <p>Results: We addressed three research questions: knowledge about three specific details of HPV infection that could be acquired from PHI, whether length of the PHI campaign and/or vaccination of females had any bearing on HPV knowledge, and knowledge differences between men and women regarding HPV. No female student in the 2008 cohort had completed the three-dose vaccine schedule compared to 58.4% of female students in 2009. Overall, participants’ knowledge regarding the sexually transmitted nature of HPV and its association with cervical cancer was high in both year groups. However, in both years, less than 50% of students correctly identified that HPV causes over 90% of cases of cervical cancer. Males gave fewer correct answers for these two details in 2009. In 2008 only around 50% of students recognised that the current vaccine protects against a limited subset of cervical cancer-causing HPV sub-types, although there was a significant increase in correct response among female students in the 2009 cohort compared to the 2008 cohort.</p> <p>onclusions: This study highlights a lack of understanding regarding the extent of protection against cervical cancer conferred by the HPV vaccine, even among an educated population in the UK who could have a vested interest in acquiring such knowledge. The intensive PHI campaign accompanying the first year of HPV vaccination seemed to have little effect on knowledge over time. This is one of the first studies to assess detailed knowledge of HPV in both males and females. There is scope for continued improvements to PHI regarding the link between HPV infection and cervical cancer.</p&gt