8 research outputs found
Six host-range restricted poxviruses from three genera induce distinct gene expression profiles in an in vivo mouse model
Investigation on Newcastle Disease Virus (NDV), Infectious Bursal Disease Virus (IBDV) and Avian Poxvirus (APV) in magellanic penguins in Southern region of Brazil
Genome sequences of three African swine fever viruses of genotypes I, III, and XXII from South Africa and Zambia, isolated from ornithodoros soft ticks
Here, we report the draft genome sequences of three African swine fever
viruses isolated from Ornithodoros soft ticks. Isolates LIV 5/40 (Zambia), SPEC 57
(South Africa), and RSA/2/2008 (South Africa) belong to genotypes I, III, and XXII, respectively.The South African Research Chairs Initiative of the Department of Science and Technology and National Research Foundation (NRF), South Africa, and the Defense Threat Reduction Agency of the United States Department of Defense (HDTRA1-16-1-0050).https://mra.asm.orgam2021Zoology and Entomolog
Comparative analysis of avian poxvirus genomes, including a novel poxvirus from lesser flamingos (Phoenicopterus minor), highlights the lack of conservation of the central region
Identification of a polyomavirus in Weddell seal (Leptonychotes weddellii) from the Ross Sea (Antarctica)
Avipoxviruses: infection biology and their use as vaccine vectors
<p>Abstract</p> <p>Avipoxviruses (APVs) belong to the <it>Chordopoxvirinae </it>subfamily of the <it>Poxviridae </it>family. APVs are distributed worldwide and cause disease in domestic, pet and wild birds of many species. APVs are transmitted by aerosols and biting insects, particularly mosquitoes and arthropods and are usually named after the bird species from which they were originally isolated. The virus species Fowlpox virus (FWPV) causes disease in poultry and associated mortality is usually low, but in flocks under stress (other diseases, high production) mortality can reach up to 50%. APVs are also major players in viral vaccine vector development for diseases in human and veterinary medicine. Abortive infection in mammalian cells (no production of progeny viruses) and their ability to accommodate multiple gene inserts are some of the characteristics that make APVs promising vaccine vectors. Although abortive infection in mammalian cells conceivably represents a major vaccine bio-safety advantage, molecular mechanisms restricting APVs to certain hosts are not yet fully understood. This review summarizes the current knowledge relating to APVs, including classification, morphogenesis, host-virus interactions, diagnostics and disease, and also highlights the use of APVs as recombinant vaccine vectors.</p