10 research outputs found

    Investigations of an increased incidence of non-Aspergillus invasive mould infections in an onco-haematology unit.

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    Invasive mould infections are life-threatening complications in patients with haematologic cancer and chemotherapy-induced neutropenia. While invasive aspergillosis represents the main cause of invasive mould infections, non-Aspergillus mould infections, such as mucormycosis, are increasingly reported. Consequently, their local epidemiology should be closely monitored. The aim of this study was to investigate the causes of an increased incidence of non-Aspergillus mould infections in the onco-haematology unit of a Swiss tertiary care hospital. All cases of proven and probable invasive mould infections were retrospectively identified via a local registry for the period 2007-2021 and their incidence was calculated per 10,000 patient-days per year. The relative proportion of invasive aspergillosis and non-Aspergillus mould infections was assessed. Factors that may affect invasive mould infections' incidence, such as antifungal drug consumption, environmental contamination and changes in diagnostic approaches, were investigated. A significant increase of the incidence of non-Aspergillus mould infections (mainly mucormycosis) was observed from 2017 onwards (Mann and Kendall test p = 0.0053), peaking in 2020 (8.62 episodes per 10,000 patient-days). The incidence of invasive aspergillosis remained stable across the period of observation. The proportion of non-Aspergillus mould infections increased significantly from 2017 (33% vs 16.8% for the periods 2017-2021 and 2007-2016, respectively, p = 0.02). Building projects on the hospital site were identified as possible contributors of this increase in non-Aspergillus mould infections. However, novel diagnostic procedures may have improved their detection. We report a significant increase in non-Aspergillus mould infections, and mainly in mucormycosis infections, since 2017. There seems to be a multifactorial origin to this increase. Epidemiological trends of invasive mould infections should be carefully monitored in onco-haematology units in order to implement potential corrective measures

    Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

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    Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

    Diseño y validación de una prueba para evaluar la disposición hacia el servicio al cliente. Línea de investigación e integración curricular en psicología jurídica y criminología

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    16 p.El servicio al cliente es crítico en el éxito de las organizaciones, ya que son los empleados quienes gestionan la relación entre estas y los consumidores de sus bienes y servicios; con esto, se debe tener en cuenta que la percepción que tienen los empleados es diferente a la que realizan los usuarios, por lo que se puede afirmar que la percepción de la calidad resulta de la comparación que hacen los clientes entre sus expectativas y la percepción de cómo se les ha prestado el servicio (Hirmukhe, 2012; Kheng, Mohamad, Ramayah & Mosahab, 2010). Esta percepción de calidad del servicio se ve afectada por el compromiso organizacional de los empleados, así como por su motivación y satisfacción laboral (García & Forero, 2014; Walsh & Deery, 2006).Introducción La teoría de respuesta al ítem y el modelo de Rasch Construcción de pruebas: diseño basado en la evidencia Método Resultados Discusión Referencia

    Congenital heart disease in the ESC EORP Registry of Pregnancy and Cardiac disease (ROPAC)

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    Elective surgical services need to start planning for summer pressures.

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    Medical Complications of Drug Abuse

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    Macroeconomic Ideas and Business Cycles: One Size Doesnnt Fit All

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    Dietary Polyphenols and Mitochondrial Function: Role in Health and Disease

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