The Australian Reproductive Genetic Carrier Screening Project (Mackenzie's Mission): Design and Implementation

Published: 28 October 2022Reproductive genetic carrier screening (RGCS) provides people with information about their chance of having children with autosomal recessive or X-linked genetic conditions, enabling informed reproductive decision-making. RGCS is recommended to be offered to all couples during preconception or in early pregnancy. However, cost and a lack of awareness may prevent access. To address this, the Australian Government funded Mackenzie’s Mission—the Australian Reproductive Genetic Carrier Screening Project. Mackenzie’s Mission aims to assess the acceptability and feasibility of an easily accessible RGCS program, provided free of charge to the participant. In study Phase 1, implementation needs were mapped, and key study elements were developed. In Phase 2, RGCS is being offered by healthcare providers educated by the study team. Reproductive couples who provide consent are screened for over 1200 genes associated with >750 serious, childhood-onset genetic conditions. Those with an increased chance result are provided comprehensive genetic counseling support. Reproductive couples, recruiting healthcare providers, and study team members are also invited to complete surveys and/or interviews. In Phase 3, a mixed-methods analysis will be undertaken to assess the program outcomes, psychosocial implications and implementation considerations alongside an ongoing bioethical analysis and a health economic evaluation. Findings will inform the implementation of an ethically robust RGCS program.Alison D. Archibald ... Tristan Hardy ... et al. and The Mackenzie’s Mission Study Tea

Data on spin-singlet to triplet Cooper pair converter interface

This dataset contains the measurements reported in the manuscript "Spin-singlet to triplet Cooper pair converter interface". In this study, we fuse magnetism and superconductivity in a system where spin-ordering and diffusion of Cooper pairs are achieved at a non-intrinsically magnetic nor superconducting Cu/C60 interface. Electron transport, magnetometry and low-energy muon spin rotation are used to probe time-reversal symmetry breaking in these structures

Laorientación al mercado de la universidad póblica: Un reto para el sistema Untversitario EspaÑol

Universidad pública, orientación al mercado, rivalidad, Public university, market orientation, rivalry,

Orientación al mercado y administración póblica local determinación de un modelo teórico y de medición

Orientación al mercado, gobierno local, modelo, índice, administración, receptiva, orientación al mercado proactiva, Market orientation, local government, model, index, receptive, administration, proactive market orientation,