33 research outputs found

    Diagnosis, treatment, and survival from kidney cancer: realā€world National Health Service England data between 2013 and 2019

    Get PDF
    Objectives: To report the NHS Digital (NHSD) data for patients diagnosed with kidney cancer (KC) in England. We explore the incidence, route to diagnosis (RTD), treatment, and survival patterns from 2013 to 2019. Materials and Methods: Data was extracted from the Cancer Data NHSD portal for International Classification of Diseases, 10th edition coded KC; this included Cancer Registry data, Hospital Episode Statistics, and cancer waiting times data. Results: Registrations included 66 696 individuals with KC. Incidence of new KC diagnoses increased (8998 in 2013, to 10 232 in 2019), but the ageā€standardised rates were stable (18.7ā€“19.4/100 000 population). Almost half of patients (30 340 [45.5%]) were aged 0ā€“70 years and the cohort were most frequently diagnosed with Stage 1ā€“2 KC (n = 26 297 [39.4%]). Most patients were diagnosed through nonā€urgent general practitioner referrals (n = 16 814 [30.4%]), followed by 2ā€weekā€wait (n = 15 472 [28.0%]) and emergency routes (n = 11 796 [21.3%]), with older patients (aged ā‰„70 years), Stage 4 KCs, and patients with nonā€specified renal cell carcinoma being significantly more likely to present through the emergency route (all P < 0.001). Invasive treatment (surgery or ablation), radiotherapy, or systemic antiā€cancer therapy use varied with disease stage, patient factors, and treatment network (Cancer Alliance). Survival outcomes differed by Stage, histological subtype, and social deprivation class (P < 0.001). Ageā€standardised mortality rates did not change over the study duration, although immunotherapy usage is likely not captured in this study timeline. Conclusion: The NHSD resource provides useful insight about the incidence, diagnostic pathways, treatment, and survival of patients with KC in England and a useful benchmark for the upcoming commissioned National Kidney Cancer Audit. The RTD data may be limited by incidental diagnoses, which could confound the high proportion of ā€˜emergencyā€™ diagnoses. Importantly, survival outcomes remained relatively unchanged

    Charismatic Prophecy

    No full text

    The Symbolism of Charismatic Glossolalia

    No full text

    The Use of Scripture in Practical Theology

    No full text
    corecore