Ground Penetrating Radar (GPR): an application for evaluating the state of maintenance of the building coating

Ground Penetrating Radar (GPR) is a non-destructive methodology. For the localisation of buried structures, it uses short time duration electromagnetic (EM) pulses lasting from about 1 ns to about 30 ns. Therefore, GPR is characterised by a wide frequency band ranging from 10 MHz to some GHz, and is useful in the localisation of EM discontinuities in the subsurface with high resolution. This paper describes an application of GPR to evaluate the state of maintenance of some travertine panels attached to the inside walls of a building housing the Bank of Naples in Campobasso and in danger of falling because of the numerous voids present between the wall and the panels. The aim of the survey was to assess whether the GPR technique could be used to detect the voids behind the travertine panels. The study was made to assist the design of the restoration works of the travertine covering. Because of the very narrow thickness of both the travertine plates and the voids, special care was needed in the acquisition and processing steps. The measurements were performed on two panels: one purposely put on to the laboratory wall with a known position of the voids; the other one selected from among the panels to be restored. Although pushed to the limit of the resolution achievable by the available antenna, the study has given quite good results

Application of 3D visualization techniques in the analysis of GPR data for archaeology

In this work, some results of a GPR survey carried out in a 10000 m2 large archaeological site, located in Lecce (Italy) near to a necropolis dating from the Messapian to the Roman imperial age, are reported. After a preliminary survey, performed on the entire area along parallel 1 m spaced profiles using a 200 MHz and a 500 MHz antenna in single-fold continuous mode, some smaller areas were selected, where the survey was repeated decreasing the profile spacing down to 0.50 m for the lower frequency antenna and to 0.25 m for the higher one. For two selected zones (D and B) the processed data were visualized in 3D space not only by the standard time slice technique, but also by two recently proposed approaches, namely by iso-amplitude surfaces of the complex trace amplitude and by 3D projection of energy and envelope stacks. The immediacy in revealing the spatial positioning of highly reflecting bodies, such as the anomaly interpreted as an old refilled cistern in zone D, makes 3D visualization techniques very attractive in archaeological applications of GPR. Their sensitivity to the signal/noise ratio is, on the other hand, highlighted by the quite poor performance in zone B, where the only reliable result provided by all the techniques was the soil/bedrock reflection, whereas none of them could effectively enhance the visibility of weak dipping reflections noted on 2D sections and probably related to fractures or bedding planes in the calcarenitic basement. The performance of the various techniques in these two different situations allowed insights into their main advantages and drawbacks to be gained

Integrated geophysical and geological investigations applied to sedimentary rock mass characterization

The Salento Peninsula (south-eastern Italy) is characterized by sedimentary rocks. The carbonatic nature of the rocks means they are affected by karst phenomena, forming such features as sinkholes, collapsed dolines and caverns, as a result of chemical leaching of carbonates by percolating water. The instability of these phenomena often produces land subsidence problems. The importance of these events is increasing due to growing urbanization, numerous quarries affecting both the subsoil and the surface, and an important coastline characterized by cliffs. This paper focuses on geological and geophysical methods for the characterization of soft sedimentary rock, and presents the results of a study carried out in an urban area of Salento. Taking the Q system derived by Barton (2002) as the starting point for the rock mass classification, a new approach and a modification of the Barton method are proposed. The new equation proposed for the classification of sedimentary rock mass (Qsrm) takes account of the permeability of the rock masses, the geometry of the exposed rock face and their types (for example, quarry face, coastal cliff or cavity), the nature of the lithotypes that constitute the exposed sequence, and their structure and texture. This study revises the correlation between Vp and Q derived by Barton (2002), deriving a new empirical equation correlating P-wave velocities and Qsrm values in soft sedimentary rock. We also present a case history in which stratigraphical surveys, Electrical Resistivity Tomography (ERT), and seismic surveys were applied to in situ investigations of subsidence phenomena in an urban area to estimate rock mass quality. Our work shows that in the analysis of ground safety it is important to establish the rock mass quality of the subsurface structures; geophysical exploration can thus play a key role in the assessment of subsidence risk

Spectrophotometric properties of dwarf planet Ceres from the VIR spectrometer on board the Dawn mission

We study the spectrophotometric properties of dwarf planet Ceres in the VIS-IR spectral range by means of hyper-spectral images acquired by the VIR imaging spectrometer on board the NASA Dawn mission. Disk-resolved observations with a phase angle within the $7^{\circ}<\alpha<132^{\circ}$ interval were used to characterize Ceres' phase curve in the 0.465-4.05 $\mu$m spectral range. Hapke's model was applied to perform the photometric correction of the dataset, allowing us to produce albedo and color maps of the surface. The $V$-band magnitude phase function of Ceres was fitted with both the classical linear model and H-G formalism. The single-scattering albedo and the asymmetry parameter at 0.55$\mu$m are $w=0.14\pm0.02$ and $\xi=-0.11\pm0.08$, respectively (two-lobe Henyey-Greenstein phase function); the modeled geometric albedo is $0.094\pm0.007$; the roughness parameter is $\bar{\theta}=29^{\circ}\pm6^{\circ}$. Albedo maps indicate small variability on a global scale with an average reflectance of $0.034 \pm 0.003$. Isolated areas such as the Occator bright spots, Haulani, and Oxo show an albedo much higher than average. We measure a significant spectral phase reddening, and the average spectral slope of Ceres' surface after photometric correction is $1.1\%k\AA^{-1}$ and $0.85\%k\AA^{-1}$ at VIS and IR wavelengths, respectively. Broadband color indices are $V-R=0.38\pm0.01$ and $R-I=0.33\pm0.02$. H-G modeling of the $V$-band magnitude phase curve for $\alpha<30^{\circ}$ gives $H=3.14\pm0.04$ and $G=0.10\pm0.04$, while the classical linear model provides $V(1,1,0^{\circ})=3.48\pm0.03$ and $\beta=0.036\pm0.002$. The comparison with spectrophotometric properties of other minor bodies indicates that Ceres has a less back-scattering phase function and a slightly higher albedo than comets and C-type objects. However, the latter represents the closest match in the usual asteroid taxonomy.Comment: 14 pages, 20 figures, published online on Astronomy and Astrophysics on 13 February 2017. Revised to reflect minor changes in text and figures made in proofs, updated value of V-R and R-

Osteochondritis dissecans of the knee. Pearls and pitfalls of anatomical reduction and secure fixation

Osteochondritis dissecans of the knee is characterized by sterile necrosis of the subchondral bone and typically affects skeletally immature patients. When left untreated, osteochondritis dissecans can lead to early-onset osteoarthritis, resulting in pain and disability. This study shows the pearls and pitfalls of an arthroscopic technique of fixation performed successfully using a bioabsorbable nail for unstable osteochondritis dissecans lesions located in the medial femoral condyle of the knee

Application of 3D visualization techniques in the analysis of GPR data for archaeology

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Anterolateral ligament reconstruction does not delay functional recovery, rehabilitation, and return to sport after anterior cruciate ligament reconstruction. A matched-pair analysis from the SANTI (Scientific ACL Network International) Study Group

Purpose: To determine whether the addition of an anterolateral ligament reconstruction (ALLR) resulted in delayed functional recovery (based on the Knee Santy Athletic Return to Sport [K-STARTS] score) at 6 months after anterior cruciate ligament reconstruction (ACLR). Methods: A retrospective analysis of prospectively collected data from consecutive pa- tients who underwent an ACLR between September 2017 and December 2020 was conducted. Patients who received an isolated hamstring autograft (isolated ACLR group) were propensity matched in a 1:1 ratio to patients who received a hamstring autograft ACLR combined with an ALLR (ACLR-ALLR group). Outcome measures included the Tegner Activity Scale and the K-STARTS testda validated composite return-to-sports test (including the Anterior Cruciate LigamenteReturn to Sport After Injury scale, Qualitative Assessment of Single-Leg Landing tool, limb symmetry index, and ability to change direction using the Modified Illinois Change of Direction Test). Results: The study included 111 matched pairs. At 6 months postoperatively, there were no significant differences between groups in the overall K-STARTS score (65.4 for isolated ACLR vs 61.2 for ACLR-ALLR, P 1⁄4 .087) or the Tegner Activity Scale score (3.7 for isolated ACLR vs 3.8 for ACLR-ALLR, P 1⁄4 .45). In addition, an evaluation of the subscales of the K-STARTS score revealed no disadvantage across the domains of neuromuscular control, limb symmetry index, agility, or psychological readiness to return to sport when an ALLR was performed. Conclusions: The addition of ALLR at the time of ACLR does not delay functional recovery. Spe- cifically, at 6 months postoperatively, there was no disadvantage in patients undergoing ALLR-ACLR, when compared with those undergoing isolated ACLR, with respect to neuromuscular control, limb symmetry indices (hop tests), agility, or psychological readiness to return to sport

The Mineralogy of Ceres’ Nawish Quadrangle

Quadrangle Ac-H-08 Nawish is located in the equatorial region of Ceres (Lat 22°S-22°N, Lon 144°E- 216°E), and it has variable mineralogy and geology. Here, we report on the mineralogy using spectra from the Visible and InfraRed (VIR) mapping spectrometer onboard the NASA Dawn mission. This quadrangle has two generally different regions: the cratered highlands of the central and eastern sector, and the eastern lowlands. We find this dichotomy is also associated with differences in the NH_4-phyllosilicates distribution. The highlands, in the eastern part of the quadrangle, appear depleted in NH_4-phyllosilicates, conversely to the lowlands, in the north-western side. The Mg-phyllosilicates distribution is quite homogeneous across Nawish quadrangle, except for few areas. The 2.7 µm band depth is lower in the south-eastern part, e.g. in the Azacca ejecta and Consus crater ejecta, and the band depth is greatest for the Nawish crater ejecta, and indicates the highest content of Mg-phyllosilicates of the entire quadrangle. Our analysis finds an interesting relationship between geology, mineralogy, topography, and the age in this quadrangle. The cratered terrains in the highlands, poor in NH_4 phyllosilicates, are older (̴2 Ga). Conversely, the smooth terrain, such as with Vindimia Planitia, is richer in ammonia-bearing phyllosilicates and is younger (̴1 Ga). At the local scale, Ac-H-8 Nawish, displays several interesting mineralogical features, such as at Nawish crater, Consus crater, Dantu and Azzacca ejecta, which exhibit localized Na-carbonates deposits. This material is superimposed on the cratered terrains and smooth terrains and shows the typical depletion of phyllosilicates, already observed on Ceres in the presence of Na-carbonates

Novel large-range mitochondrial dna deletions and fatal multisystemic disorder with prominent hepatopathy

Hepatic involvement in mitochondrial cytopathies rarely manifests in adulthood, but is a common feature in children. Multiple OXPHOS enzyme defects in children with liver involvement are often associated with dramatically reduced amounts of mtDNA. We investigated two novel large scale deletions in two infants with a multisystem disorder and prominent hepatopathy. Amount of mtDNA deletions and protein content were measured in different post-mortem tissues. The highest levels of deleted mtDNA were in liver, kidney, pancreas of both patients. Moreover, mtDNA deletions were detected in cultured skin fibroblasts in both patients and in blood of one during life. Biochemical analysis showed impairment of mainly complex I enzyme activity. Patients manifesting multisystem disorders in childhood may harbour rare mtDNA deletions in multiple tissues. For these patients, less invasive blood specimens or cultured fibroblasts can be used for molecular diagnosis. Our data further expand the array of deletions in the mitochondrial genomes in association with liver failure. Thus analysis of mtDNA should be considered in the diagnosis of childhood-onset hepatopathies

Not only dominant, not only optic atrophy: expanding the clinical spectrum associated with OPA1 mutations

Background: Heterozygous mutations in OPA1 are a common cause of autosomal dominant optic atrophy, sometimes associated with extra-ocular manifestations. Few cases harboring compound heterozygous OPA1 mutations have been described manifesting complex neurodegenerative disorders in addition to optic atrophy. Results: We report here three patients: one boy showing an early-onset mitochondrial disorder with hypotonia, ataxia and neuropathy that was severely progressive, leading to early death because of multiorgan failure; two unrelated sporadic girls manifesting a spastic ataxic syndrome associated with peripheral neuropathy and, only in one, optic atrophy. Using a targeted resequencing of 132 genes associated with mitochondrial disorders, in two probands we found compound heterozygous mutations in OPA1: in the first a 5 nucleotide deletion, causing a frameshift and insertion of a premature stop codon (p.Ser64Asnfs*7), and a missense change (p.Ile437Met), which has recently been reported to have clinical impact; in the second, a novel missense change (p.Val988Phe) co-occurred with the p.Ile437Met substitution. In the third patient a homozygous mutation, c.1180G > A (p.Ala394Thr) in OPA1 was detected by a trio-based whole exome sequencing approach. One of the patients presented also variants in mitochondrial DNA that may have contributed to the peculiar phenotype. The deleterious effect of the identified missense changes was experimentally validated in yeast model. OPA1 level was reduced in available patients\u2019 biological samples, and a clearly fragmented mitochondrial network was observed in patients\u2019 fibroblasts. Conclusions: This report provides evidence that bi-allelic OPA1 mutations may lead to complex and severe multi-system recessive mitochondrial disorders, where optic atrophy might not represent the main feature